I’ve mostly tried to avoid the Covid origins debate, but I listened to a very good Guruspod episode, where they covered this. It was an interview with Eddie Holmes, Kristian Andersen, and Michael Worobey, and was partly intended as a response to a Sam Harris podcast with Matt Ridley and Alina Chan.
I encourage you to listen, but they did highlight a couple of things that I thought were particularly interesting. For example, some argue that it’s too much of a coincidence that the Covid virus emerged in a city that has a lab that happens to study coronaviruses. They point out that, firstly, given the properties of the virus, it was almost certainly going to start spreading in a big city, and that Wuhan was certainly amongst the cities in which you might expect such an outbreach to start. Secondly, many of the major cities in which you might expect such an outbreach to start have labs that could, after the fact, seem to be coincidental.
The suggestion is that the most likely origin was a spillover to humans in the Huanan Seafood Market. In fact, the evidence indicates two separate spillover events involving two closely related variants. It could be that someone was infected in the lab and then spread the virus in the market. This, however, becomes less likely if it happened twice. This doesn’t preclude some kind of lab origin, but the overall evidence seems to point much more strongly to a zoonotic origin with the spillover occuring in this market.
However, what I found particularly interesting was the similarities with the climate debate. Those who dispute the mainstream view use emails taken out of context. Many of the scientists who become prominent are publicly attacked. There are claims that the scientific community somehow benefits from promoting a particular narrative. There are claims that dissenting views are silenced and that the mainstream scientific community are not willing to debate these alternative ideas. There are arguments that continually get repeated despite having been debunked time and time again. There are non-experts who suddenly think they know better than experts. In fact, some of these people are the same as in the climate debate (Matt Ridley, for example).
Even though I am a scientist, I certainly have no relevant expertise in this context. I’m having to rely on heuristics to try and get some sense of what is most likely. My general sense is that it’s now pretty clear that the virus could not have been engineered and that some other kind of lab leak is much less likely than the origin being transmission from animals to people in the seafood market. My heuristic is essentially that this seems to be the view of relevant experts and that they seem to present arguments that make sense, that acknowledge uncertainty, and that are well thought out.
My other heuristic is that some who appear to be on the other side of the debate have held similarly contrarian positions with regards to climate change. Past evidence would seem to indicate that they’re not particularly skilled at objectively assessing evidence, and are perfectly comfortable promoting views that most with relevant expertise would regard as obviously wrong.
This doesn’t mean that my current assessment is correct, but it currently seems more likely that the experts are right, than those who hold contrarian views and have been wrong before.
More recently, both the FBI and the Energy Department believe the lab leak is most likely.
https://www.bbc.com/news/world-us-canada-64806903
Richard,
Yes, which is why this has become topical. As I understand it, there are other Federal agencies who disagree and, unless I’m mistaken, the evidence that the FBI and Energy Department used is not publicly available.
Personally, if I was an autocrat attempting to cast an aura of infallibity and who’d thereby attempted to engineer a coverup of the inexorable spread of a novel and highly infectious virus and thereby hastened and amplified a global disaster, I’d be delighted that folks are obsessing over a question offering endless possibilities for distraction from the main useful lesson we might learn from the event.
Trying to wish away an epidemic by jailings etc. led us straight into the jaws of needless misery.
One way or another and especially given pressures on the natural environment etc. we’re going to have this problem again, pretty much as an inevitability. Universal spotlighting and condemnation of how this particular autocrat’s weakness and insecurity led us to incalculable loss of various kinds is arguably a more useful outcome than identifying which horse escaped whatever stable door. Let’s make that a more reluctant choice.
Doug,
Indeed, whatever the origin, we’re likely to face another such pandemic in the not too distant future (unfortunately). We should at least be focussing on how we can deal with this more effectively in the future, and what sort of things we should be doing to minimise the impact. Understanding the origin may still be important, but we should be careful of it becoming too much of a distraction.
With the reality of our effective communal governance stopping at national borders (given our arrested development of governmental jurisdictional hierarchy at national borders) I just can’t see how knowing precisely where and how the virus originated offers any effective lever of control, if this pandemic was indeed an accidental artifact of intentional human processes.
Supposing that we could determine with 100% certainty that this particular pathogen originated at the lab in question via whatever means and for whatever purposes, what does that information afford us in terms of avoiding a repeat? We have no effective mechanism for preventing this kind of activity behind sovereign borders.
Meanwhile, we’ll continue our collision with the natural world. Markets for food products drawn directly from wildlife are more amenable to agreement on conventions but it would be foolish to assume our control of outcomes arising from that are fully within our grasp. Then there’s plain old “bad luck,” along the lines of ebola outbreaks, fully accidental as a result of population pressures etc.
To me it seems our best and most effective efforts can be devoted to what happens _after_ an emergence, given broad agreement that C19 is only one example we’ll be facing. The first thing to practice with regard to that is surely to avoid denial. The particular autocrat in question here went straight to denial of facts and we can see the plain result of that.
We don’t have law to deal with this but serious loss of face is a powerful weapon. This autocrat should be recorded in history as a fool of historical proportions, so as to deter others tempted to go down the same path.
The fact that most climate deniers are also COVID deniers discredits them on both subjects, as far as I’m concerned. This proves it’s their mindset, not anything to do with science. Not that they’re very convincing on either topic.
Richard Arrett: “The nation’s intelligence agencies are split, and none of them changed their conclusions after seeing the Energy Department’s findings, officials said.”
“Of nine intelligence community entities that have reviewed SARS-CoV-2 origin data, only two—the DOE and the FBI—have tilted toward a lab leak. Five favor the hypothesis of a natural “spillover” event from wild animals (four agencies and the National Intelligence Council), while the remaining two entities say there is not enough data to sway opinions toward either hypothesis.”
https://arstechnica.com/science/2023/03/who-deeply-frustrated-by-lack-of-us-transparency-on-covid-origin-data/
Off with the old, here is the new true Covidball frontier:
https://www.vox.com/future-perfect/2023/2/22/23609499/masks-covid-coronavirus-cochrane-review-pandemic-science-studies-infection
There’s also the Cochrane paper, which is now making the rounds at Roy’s thanks to BrettS.
David,
Indeed, it’s possible that they could be right in one circumstance, despite being wrong in others, but it does seem unlikely. And, as you say, it does suggest that factors other than the scientific evidence have a strong influence on their views (which is maybe true for all of us, to a certain extent).
The distinction is that deniers aren’t seeking to place blame on someone for climate change, since they claim it’s all natural and God’s will and all that hocus-pocus. Placing blame is part of their political strategy.
Actually both are along the lines of conspiracy ideation. Anything any governmental body or academia says now immediately jumps into cospiracy nutter territory.
Question everything, accept nothing.
Doug,
Indeed, whatever the origin, we’re likely to face another such pandemic in the not too distant future (unfortunately). We should at least be focussing on how we can deal with this more effectively in the future, and what sort of things we should be doing to minimise the impact.
1. collecting batshit from the hinterlands of china and returning it to high population areas for “work” in a BSL2 lab
is suboptimal.
2. the Predict program was a bad idea regardless
three facts stick out
1. there were cases in september, not associated with the market
2. the labs control was turned over to the military in september
3. then the lab had contractors in to————————–
refurbish and replace the ventelation system.
oh ya, the lab deleted their database of sequences in september
Yeah, let the conspiracy ideation keep on truckin’ Moshpit.
I’m hearing echoes of the Iraq WMD fiasco – there looks like a pervasive US intent to demonise China; under such social/political circumstance (any STS take on it?) evidence isn’t necessarily an essential requirement. Or able to be viewed objectively.
Certainly an increasingly powerful China that feels entitled to use covert and overt use of force across the world to advance it’s interests the way the US has is a frightening prospect but I’m struggling to see how popularising fear and suspicion and loathing of China helps.
Willard, the Cochrane review on masks is very flawed. There’s been a lot written about this that spells out why. See, for example
“Masks Reduce the Risk of Spreading of COVID, Despite a Cochrane Review Saying They Don’t,” C Raina MacIntyre et al, The Conversation 2/6/23.
https://theconversation.com/yes-masks-reduce-the-risk-of-spreading-covid-despite-a-review-saying-they-dont-198992
which says
“An updated Cochrane Review suggests face masks don’t reduce the spread of COVID in the community. But there are several reasons why this conclusion is misleading.”
I think that’s the only part of your writing that goes above and beyond what I would have felt comfortable writing on a blog.
You admit no expertise here (and that goes double for me.) I don’t feel I could justify weighing in. At all. And I’m not sure why you feel stating your own current preference is appropriate.
You know full well that one (not the only, by any measure) explicit and well-understood requirement in science is to allow appropriate time for consensus to form. That takes time. That time hasn’t yet arrived (obviously.) That’s really all us lay people can assess right now. And going beyond that, at this time, is just us lay folks stirring pots. Which we shouldn’t do. (My opinion.)
I’ve noticed that no one here has yet mentioned Segreto & Deigin’s early 2020 paper on the topic. It’s available here:
https://onlinelibrary.wiley.com/doi/full/10.1002/bies.202000240
Their paper currently has 128 citations according to google scholar (all sides of the issue, I imagine.)
Find this, for example:
The authors also wrote a rebuttal to criticism by Tyshkovskiy & Panchin (DOI: 10.1002/bies.202000325):
Click to access 2106.02020.pdf
Finally, in the public arena, there was also this WSJ article that hit the news circuit:
https://www.wsj.com/amp/articles/the-science-suggests-a-wuhan-lab-leak-11622995184
It may appear from what I just included above (and what I didn’t include) that I have a different take. That would be far from the truth.
I just would feel very uncomfortable writing as you did in the blog. I feel it is better to simply allow appropriate experts the time they need.
The basic problem is that, so far as I’m aware, there’s no firm a priori criteria or, better still, clear natural demarcations (evidence from nature itself showing clear, wide separations which are, I believe, far better to have than ‘a priori’ human-constructed criteria) for what it means for a virus to be natural or lab-generated.
What I do know for sure is that all this stuff is well outside of my league.
(Yes, I’m as curious as the next and would like a firm answer one way or another. Either way, it’s important. But I just don’t think enough time has arrived.)
Jon,
ATTP will have to answer your basic why comment, all I can say is that there may never be a definitiave answer to this question. Oh and China hating in the USA is all the rage now. They took our jobs!
Well, I wouldn’t say never. But I’m certainly not holding my breath, either. 🙂
Yet? Who knows what the future may bring?
When I look back over what’s been learned just in the last 10 years? I can only imagine what the next 10 may bring. A clear natural demarcation may yet be found. If so, then we may have a reasonably solid answer.
But I agree that it’s not likely to arrive any time soon.
It’s just so much easier to hunt for and find somebody to blame than to work together to find and execute solutions. This argument is a dangerous distraction, and the usual suspects are out in force.
350,000 – Three Hundred and Fifty Thousand.
That’s how many man-made chemicals that are currently being dispersed into the biosphere. The scale of chemical release is estimated to be as high as 220 billion tonnes per annum – of which greenhouse emissions constitute only 20%. By the year 2050 there will be more than 500,000 chemicals and novel man-made molecules being manufactured and very few will ever be tested for their long-term effect on the environment.
https://news.mongabay.com/2022/01/weve-breached-earths-threshold-for-chemical-pollution-study-says/
There are already many reports of chemicals being responsible for causing genetic changes in species of bacteria and algae that make them deadly pathogens to marine animals. I would not discount the possibility that the next pandemic could jump from one of those infected animals to humans. It’s going to happen because we can’t stop ourselves.
I find it extraordinarily peculiar that scientists are willing to hang their hat on one sort of analysis or another without accompanying their conclusions with triple asterisks that they have been deliberately denied access to truly central avenues of investigation. I’m speaking, of course, to the CCP’s flat denial of any independent or domestic investigation into the WIV — unless you count a chaperoned 1.5 hour visit by the WHO long after they had the opportunity to scrub the place. It’s like theorizing about a murder without acknowledging that you’ve been denied access to the murder scene or any other evidence and instead rely on statistical models as to who might have been where.
I also find it strange that ATTP didn’t link to the Alina China interview but did to every other source. And as to the claim that scientists who hue to the mainstream view are subject to pushback, well, how about Alina who was the subject of torrents of abuse including death threats and claims she’s a “race traitor.”
The holes in the wet market theory are numerous. No bats or pangolins were sold there. The virus mysteriously jumped from a bat to ___ that hopped over to a human and was marvelously, *marvelously* adapted to human to human transmission from day 1. Right next to the institute that had been collecting bat viruses from all across the region and was engaging in gain-of-function research on the same. The same institute with a history of lax security (State Department memos to the same). The same lab that Jeremy Farrar responded “wild west” when another scientist asked (about WIV) ““Surely that wouldn’t be done in a BSL-2 lab?”
Gradually the facade is breaking down. Even Fauci is now claiming a lab leak would be considered a natural origin. But I digress… I have no relevant expertise.
Jon,
Because it’s a blog and I have no authority here. I don’t really think there’s any great concern that me expressing my view is going to have some kind of undue influence on others. I was mostly just trying to be honest about my current position/view.
Jon,
You’re, of course, right that we don’t yet know the answer. However, my impression (which is essentially what the blog post was about) is that most relevant experts seem to regard a spillover at the marker as being more likely than something associated with the lab. This is despite all the things that seem obviously suspicious (such as those pointed out by Steven). Why is this? Is it because these supposedly suspicious things are not actually as suspicious as they seem, or are the experts ignoring inconvenient information? My general view is that the former is more likely than the latter.
Maybe I didn’t make things as clear in the post as I should have. The point I was trying to make was that in scenarios where we have little relevant expertise, we’ll tend to use heuristics to try and assess what we trust. It’s clearly not foolproof and could end up very wrong, but we probably all do it at times, and it can be a reasonable short-cut.
My general one is that when there seems to be a rough consensus amongst experts, I will tend to trust that, than assume that it might be wrong. It could, of course, be wrong, but it’s probably the best option at the time.
Of course, you could argue that I don’t need to hold a view about some topics, and that may well be the case here. It really doesn’t matter what my views is about the origins of Covid. There are two reasons I wrote the post. One was to highlight the apparent similarities between this topic and climate change, and the others was to highlight, or suggest, that we will all tend to use short-cuts when we don’t have the expertise (or time) to assess the scientific evidence directly.
I think we all use heuristics, specialists included. The state space of solutions to explore and the sheer amount of information to process would be too big. Even if one could in principle judge the evidence directly, it would require energy that may not be worth it.
Otters rely on indirect means. In this case, Matt King Coal. That Alina decided to write a book with Matt could tell Climateball players all they need to know. Matt has been wrong on so many things. Worse, he lost so many winning positions. Is it really worth the time?
And then there is this sudden gain in confidence in the FBI. Not so long ago, we could hear contrarians say things like that:
https://judithcurry.com/2023/02/06/my-interview-with-jordan-peterson/#comment-986353
Intriguingly, that newspaper is the very same in which Brett Stephens promoted Jefferson’s conspiracy.
For contrarians, jail time is not enough to prove political interference. Now all of a sudden they believe the FBI saying stuff without providing evidence. Notwithstanding that the Department of Energy is the same that worked on Joe’s omnibus bill to speed up decarbonization. The very department they kept bashing for all 2022, is now the true hero we need to face evil with bare truths?
Nothing in that story sticks. So why not wait until contrarians produce a story that stick? As long as I do not have to work for contrarians Just Asking Questions. And no, I will not buy Matt & Alina’s book, so I don’t mind the wait until it seeps into the Discourse.
For now I have a podcast episode to finish, and would expect commenters to finish it up too before asking questions and raising concerns.
Here is an interesting article about experts interviewed off the record:
View at Medium.com
The bottom line is both hypothesis remain plausible and the investigation has been stymied by China.
Personally, I find the lab leak hypothesis most convincing. The single most important piece of evidence is what Steven Mosher pointed out – that the Chinese authorities took down the dna sequences of the viruses being worked on in the Wuhan lab. The only reason to take that down was to hide the fact that fact that they were indeed working on a virus which was close to or even identical to the Wuhan virus. If not, why take it down?
Once we get that data (if we ever do) I bet it shows the furin cleavage site, which is what made the bat virus transmissible to humans, was in a lab virus and in fact the virus was manufactured in the lab for gain of function purposes.
Obviously this has been politicized and the “experts”, like Faucci, have a vested interest in hiding that they funded the research which killed 7 million people. The emails show that a bunch of “experts” thought the lab leak was the most likely source, but Faucci leaned on them and got them all to support his view and then quickly published a paper to put forward the wet market theory. Yet, over 50,000 samples of animals later, no wet market source has been found (other than from humans who probably brought it there from the lab).
China knows the answer to this question and the fact that they are not helping with finding out what really happened tells us all we need to know about how this happened. It came from the lab. The USA paid for the research, which was banned by Obama and off shored by Faucci to get around the USA regulations, and which killed 7 million people. Faucci doesn’t want people to know this and so lies about it. Oldest story in the book.
So it is ok to speculate about this. It is ok to default to believing in the experts. But when the “experts” have conflicts of interest and are caught lying – it is also ok to change your mind. Clearly the USA paid for gain-of-function research in Wuhan. Faucci lied about that. That is a crime (since he lied under oath before Congress). Why would he do that? Because he doesn’t want history to show he killed 7 million people. Simple.
“Fauci … killed 7 million people. Simple.” Like 9/11 Truthers, there is no discussion to be had here. They’ve made up their minds, and they’re sticking to it.
There are plenty of perps out there, and they are clamoring to blame their victims.
This is neither useful nor OK. We could do working for our mutual future, but it is so much easier to create myths and find people to blame.
There are honest questions to be asked about labs, but this is a conclusion based on lies and hatred, and does us all no possible good.
> Once we get that data (if we ever do) I bet
How much, RickA?
Perhaps you should listen to the interview AT features in this blog post before giving me some odds.
Unless you are only speculating that Fauci killed 7M people? But right – that’s not exactly what you said. You only said *if* he was responsible for &c. Not that you have any evidence.
Who needs evidence to accuse someone of having killed millions of people in a counterfactual world?
Sometimes I really wonder if you went to law school.
All I can add is that Le Monde Diplomatique noted in 2017 , something much repeated in 2021.
During his visit to China in 2017 , Prime Minister Cazeneuve visited the P4 lab then under construction in Wuhan because it was designed by French pharma engineers at Institut Merieux .
The biohazard containment facility was commissioned in 2018 and shortly thereafter Institut Merieux started warning the Chinese Academy , its partner in the construction project, and the facilty’s operators about the danger of deviating from its security protocols— its flight manual if you will.
A year later the first cases of covid 19 appeared in Wuhan.
It might be prudent to recall that biology is no great respecter of security protocols, military or civilian : in a 1979 a leak from a Soviet biowarfare lab in Ekaterinburg ( then Sverdlovsk ) was blamed for 66 civilian anthrax fatalities
Susan:
We are all biased. I am biased. You are biased.
It is a fact that gain of function research was banned in the USA by Obama. It is a fact that Faucci got around the USA ban by off shoring gain of function research to China. It is a fact that the lab was working on bat coronaviruses and doing gain of function research on them.
If it turns out that the pandemic virus escaped from the Wuhan lab, based on research funded by Faucci – will you agree that Faucci is at fault for the pandemic? I apply the but for test – but for the funded research there would not have been a pandemic. So that is how I lay this at Faucci’s feet. The fact that he lies about his role is telling.
I think Obama was correct to ban gain-of-function research. The pandemic shows the risks and there have been no benefits that I am aware of. So the cost benefit is pretty clear. It should be banned world-wide. Would you agree gain-of-function research with viruses should be banned?
Anyway – I suspect more and more information will continue to come out about this and it will be harder and harder for people like yourself to say I am lying and basing my opinion on hatred. I am simply looking at the facts and coming to my own conclusion (like ATTP).
Cool story, Russell.
Which P4 lab, again?
[I asked for odds, RickA. Not for you to exploit my comment to once again cry murder empty handed. -W]
I listened to the podcast, in its entirety, yesterday. Actually quite compelling at this point in time. I’d recommend all people listen to it but please leave Grand Conspiracy Station first.
Oh and if this happened anywhere else in the world than China, say in the USA, I fully would expect even higher levels conspiracy ideation than we have seen to date.
Paranoia will destroy you.
RickA,
I would suggest you listen to the podcast as everything you said above was addressed in that podcast. Everything.
Everett:
Sure – I will listen to it.
Willard:
I thought you asked if I was speculating.
I asked for odds, RickA. Real betting odds. That would help determine how much weight you put on the plausibility of your counterfactual. If you could tell me how much of your assets you would be willing to bet, it would tell me about the risk you would be willing to take.
There is no need to ask if you are speculating. You obviously are.
You can start the podcast at the 45th minute. The BSL4 and other minor red herrings are covered, preparing for the argument that a lab leak springing out of a faraway wet market would be an unlucky event.
At 1:00 there is the database thingy.
“Every accusation is a confession” – I’m willing to entertain the notion that there is some involvement of the lab, but to leap tall buildings in a single bound and conclude that blames those trying to do good and exonerates those who are in evidence promoting harm adds to the confusion rather than resolving it. (See for example Tucker Carlson, Marjorie Taylor Greene, etc. etc.) My disgust is real, I’ve been paying attention for years to all the information pouring in from a variety of sources. There is no question in my mind that lies travel halfway around the world while the truth is still trying to tie its shoelaces. Science and evidence are taking a beating as lies are being given “equal” time. This is harmful, even evil.
My original suggestion remains: that we all stop trying to nail blame to the mast and move towards working together to solve things.
Blame is easy, and all too often wrong. Helping each other is humanity at its best.
In Yap, et al’s “The design of artificial retroviral restriction factors” (May 2007) you can find phrases like this:
In Table 1 of that paper, a bevy of double-CGG tagged sequences are listed out. I believe the WSJ article (with experts writing it) point out that double-CGG is naturally suppressed but that in lab work it’s often used because it is readily available, convenient, long experience inserting it, and it creates a useful beacon to permit tracking.
Looking from the outside, does this mean anything? I’ve no place to say.
The public is getting an eyeful of expert debates. Millions have died and news loves this stuff. It generates clicks and that generates cash. But those of us who understand a little better (in our own individual ways) the processes of science and the need to allow time for consensus? Especially in such a politically divisive area and where it is obvious that more time is required?
I don’t think our lay opinions are helpful. In her usual dense and effective writing Susan A. here puts key points in play: the lay discussion is a ‘dangerous distraction’ and the goals should be to ‘find and execute solutions.’
And I think many of us understand this better than most. Or should.
Years ago, I was part of a small email group of scientists who’d found each other over a mutual interest in evolutionary processes. It lasted about 10 years and we’d write almost every few days to each other about some topic or another. I learned a lot. One of them was a CIA language specialist (in Russian) but also a micro-biologist working in a lab in Nevada. We got onto the topic (somehow) about chemical weapons and nuclear weapons. (Don’t remember how it happened.) I definitely remember when she shared her opinion, though!
She (her name was also Susan, come to think of it) first gave us context. She said that at the CIA the focus was on those with motive and opportunity. That was key. So, she pointed out that what made their job easier with chemical and nuclear was that while there were a great many actors with motive, there were only a few such actors with opportunity. Not only is delivery a problem, but so is the development without enough evidence accumulating to make detection much easier. With that context, she then added that with bio-weapons the problem is that even someone with no more than a bachelors in microbiology and a kitchen with a pressure cooker could go into their backyard and get all the necessary genetic material to make something. The supplies are readily available. And today, so are the tools. (I’m on several manufacturers’ lists as someone interested in buying such supplies and tools, so I regularly get their ads in my email.)
The problem, she said, is that now the sheer number of people or groups possessing both motive and opportunity is so large that no security agency can track it with much confidence. It was her opinion that chemical and nuclear was “manageable.” But that bio was not and probably eventually couldn’t be. That’s what she worried most about.
I remember pointing out, at the time, that perhaps the best we can hope for is to reduce motive: avoiding acting in ways that tend to create it and do what can be done to mitigate that which exists. I didn’t think beyond that point, then.
I mention all this because of Susan’s ‘find and execute solutions’ part.
The problems the planet faces are myriad. One of them, and it is a significant one, is bio. We need to focus on developing and exploring viable solutions. Part of that exploration will include a continued evaluation (by experts) about wet markets and bio-research labs, since this may help better understand part of what those solutions may look like. But that exploration will have wider scope, too. And that’s for the experts to deal with, I think.
I originally quoted this:
So. There is settled consensus, you are privy to, it is had by “the experts”, and any contrarian view must by definition not be from an expert? And as if the sentence didn’t already carry enough water for you, you added that contrarians have been wrong before. (Experts have been wrong before, scientists and science-as-settled-consensus have been wrong before, and Einstein was wrong about most things. None of that means we don’t actively study and listen and learn from science or scientists.)
I honestly could not have packed more troublesome innuendo into a sentence fragment. It’s a good debate skill because by the end of debate the opposition would have no idea how they lost so badly. But they did because they failed to see the foundation bricks being laid earlier and challenge them as they were being placed. Too late, afterwards.
In climate and in bio, we need to focus on developing achievable steps that move us closer towards solution goals. We can differ on those exact goals and our worldviews that bring us there, but I think we can still find commonly shared steps to take.
And hopefully, we will allow experts in relevant fields the time and money they require to inform us better.
Willard:
The P4 in the Wuhan Institute of Virology:
From the WPost Sept 7 2021:
Inside the Wuhan lab: French engineering, deadly viruses and a big mystery
Eva Dou,Pei Lin Wu,Quentin Aries and Rebecca Tan
One chilly morning in February 2017, a tall Chinese scientist in his 50s named Yuan Zhiming showed Bernard Cazeneuve, then the French prime minister, around Wuhan’s new high-security pathogen lab.
Built with French engineering, it was China’s first P4 lab, one of several dozen in the world with that highest security designation. Yuan, the director of the lab, had worked more than a decade to make it a reality.
Yuan and his colleagues at the Wuhan Institute of Virology (WIV) hoped they could help prevent another catastrophe like the SARS outbreak in 2003, which embarrassed Beijing and resulted in the dismissal of the health minister.
But just a couple of years after the P4 lab’s ribbon-cutting, China was engulfed in a far deadlier outbreak. Yuan’s team hadn’t prevented it. And worse, some suspected they might have been involved in its genesis.
Yuan has vociferously denied that the WIV had any part in the coronavirus pandemic’s origins. “The Wuhan P4 lab has never seen any laboratory leaks or human infections since it began operating in 2018,” Yuan said at a news conference in July…
Jon,
I might be missing what you’re suggesting. However, if you’re suggesting that we should rely on the experts and, ideally, wait for some kind of consensus to emerge, then I agree. Maybe where we disagree is that my understanding is that the general consensus amongst experts is that some kind of natural spillover is more likely than some kind of lab leak. I may, of course, be wrong and maybe this consensus isn’t very strong. So, maybe we should wait a bit longer before commenting, but I’m certainly not trying to express some kind of view that is at odds with the current view of experts.
Russell,
P4 labs are not for coronaviruses.
Your turn.
Indeed, one of the key points being made in the podcast is that even though the Wuhan lab is one of the few with a BSL4 lab, it’s irrelevant in this context because coronaviruses are not studied in BSL4 labs. Of course, I haven’t independently confirmed this, but it was what the experts on the podcast claimed.
As said in the podcast level 3 is what the rest of the world uses, e.g:
https://www.cdc.gov/coronavirus/2019-ncov/lab/lab-biosafety-guidelines.html
The Wuhan researchers prolly used a BSL-2, which is far from being a dentist office according to the researchers interviewed.
Perhaps you should have mentioned that one of them signed a letter asking that we delve into the lab leak hypothesis, AT.
Willard,
Indeed, that was discussed quite extensively in the podcast.
That researcher also found that the letter discussed in that previous post was worded too strongly:
Willard, what in the name of credible denial was Yuan trying to do when he told that news conference on the pandemic’s origins:
“The Wuhan P4 lab has never seen any laboratory leaks or human infections since it began operating in 2018,”
The facility was built to avoid a repeat of the WIV 2003 SARS leak. Given the French complaints about failure to adhere to containment protocols, relegating covid research to the older and already problematic P3 containment, instead of the Ebola and smallpox rated P4 seems to have been a Bad Mistake.
Russel,
The point being made in the podcast was that some (apparently) have suggested that it’s too much of a coincidence that Covid emerged in a city with one of the only BSL4 labs, but that that isn’t really relevant since coronaviruses are not studied in BSL4 labs.
Chinese authorities even denied there was a live animal market in Wuhan and dismissed photos of them as fake, Russell. Photos that were circulated by one of the researchers interviewed by Chris & Matt.
Further whataboutism might be bolstered by listening to the podcast episode.
And here is the letter:
https://www.science.org/doi/10.1126/science.abj0016
Let readers find the name of the podcast guest in it.
As a clue, here is one paper that scientists published afterwards:
https://www.science.org/doi/10.1126/science.abp8715
If scientists wanted not to discuss the lab leak hypothesis, they are doing it wrong.
For some reason Alina jumped the shark around that time.
Incentives, perhaps.
This is also quite a good article.
https://www.npr.org/sections/goatsandsoda/2023/02/28/1160162845/what-does-the-science-say-about-the-origin-of-the-sars-cov-2-pandemic
Continuing to pound my drum marked “what matters is what happens after a virus emerges,” via a timely item in PNAS.
“How to avoid a local epidemic becoming a global pandemic”
https://www.pnas.org/doi/abs/10.1073/pnas.2220080120?af=R
Notably, the advice therein is foreclosed as an avenue for mitigation when an autocrat attempting to create an illusion of infallibility goes into denial mode.
Meanwhile I’m still struggling to understand the practical use of knowing exactly the whys and wherefores of our topical virus’s origins. If/when that is ascertained, how will that information be of practical use in terms of plausible efficacy? What is the objective of this identification? Supposing that a secret operation’s cover was blown by escape of this pathogen, how does our knowing that apply to the next event? Will resolving the questions end such secrecy?
Human nature is going to happen. What do we do after that inexorability? Surely our effort is better devoted to answering that?
> I’m still struggling to understand the practical use of knowing exactly the whys and wherefores of our topical virus’s origins.
Whodunnit stories sell, e.g.:
https://www.bmartin.cc/dissent/documents/AIDS/River/Prospect.html
You will never guess who wrote this, vintage 2000.
Hint: he bankrupted the first English bank in 150 years.
Words fail me:
However, what I found particularly interesting was the similarities with the climate debate. Those who dispute the mainstream view use emails taken out of context. Many of the scientists who become prominent are publicly attacked. There are claims that the scientific community somehow benefits from promoting a particular narrative.
its post normal
> I’m still struggling to understan and investigate if we can find the next pandemic
d the practical use of knowing exactly the whys and wherefores of our topical virus’s origins.
in the community there was a heated debate over the wisdom of projects like the predict project. basically “pay us to gather batshit and investigate if we can find the next pandemic
read the eco alliance grant description i posted it at the very start of this crap no help sorry its out there.
basically “we told you so!!!!!!!!!!!!!! we warned you that trying to predict or find the next deadly virus was dangerous!!! or risky!!!!
people who support safe research want to understand the risk
> its post normal
Some might call it Twitter.
Am watching this:
In any event, it is PoNo all the way down.
f/when that is ascertained, how will that information be of practical use in terms of plausible efficacy? What is the objective of this identification? Supposing that a secret operation’s cover was blown by escape of this pathogen, how does our knowing that apply to the next event? Will resolving the questions end such secrecy?
1. if the wuhan lab was doing gain of function, using humanized mice that Baric
gave to them. that would suggest poor oversight by the principle investigator
from Eco health.
you guys have no idea how easy it is to misuse grant funds. government
ask you to bid on X collecting batshit
you bid 2 million. you know the job will only cost 1 million. but usa does not
audit chinese firms for compliance with FAR or do FAR accounting.
dont ask me to explain this.
https://frohsinbarger.com/government-contractor-fraud/illegal-billing-and-cost-shifting/
you finish the X job for 1 million, you now have 1 million to play with.this money cannot be returned, you just work on Y and bill to X.
eco health alliance did a subgrant to chinese lab. bad bad idea. UNC gave them humanized mice. bad bad idea.
this is the limited hangout being proposed
As a clue, here is one paper that scientists published afterwards:
As 2019 turned into 2020, a coronavirus spilled over from wild animals into people, sparking what has become one of the best documented pandemics to afflict humans. However, the origins of the pandemic in December 2019 are controversial. Worobey et al. amassed the variety of evidence from the City of Wuhan, China, where the first human infections were reported. These reports confirm that most of the earliest human cases centered around the Huanan Seafood Wholesale Market. Within the market, the data statistically located the earliest human cases to one section where vendors of live wild animals congregated and where virus-positive environmental samples concentrated.
sadly it doesnt tell you how the virus got from the lab to the market and how workers from the lab infected animals at the market
Yeah, just love these conspiracy ideation Moshpit drivebys. Nature or nuture? One thing is for sure, you can’t change a tiger’s stripes.
“The Wuhan P4 lab has never seen any laboratory leaks or human infections since it began operating in 2018,”
The facility was built to avoid a repeat of the WIV 2003 SARS leak.
i take it youve never seen chinese construction
Sadly it doesn’t tell you how Moshpit got from the lab to the market and how Moskpit infected animals at the market.
conspiracy theory?
surely that cannot be the response to every scientific controversy.
the first position to get established becomes truth and every challenge to this becomes conspiracy. imagine the precedent
https://oversight.house.gov/release/covid-origins-hearing-wrap-up-facts-science-evidence-point-to-a-wuhan-lab-leak%EF%BF%BC/
Knowing the origin of COVID-19 is fundamental to helping predict and prevent future pandemics.
Select Subcommittee Chairman Brad Wenstrup opened the hearing by emphasizing how knowing the origin of the virus is essential to helping predict and prevent future pandemics, protecting health and national security, and preparing the United States for the future.
now, youd think people would learn about hiding data
“Jamie Metzl testified how China’s government destroyed samples, hid records, imprisoned Chinese journalists, prevented Chinese scientists from saying or writing anything on pandemic origins without prior government approval, actively spread misinformation, and prevented an evidence-based investigation.”
hint in china there are always 2 sets of books
We know that the GOP cherry picked everything.
Comer: “Is the possibility COVID-19 leaked from a lab a conspiracy theory?”
Witnesses answered, “No.”
> you guys have no idea how easy it is to misuse grant funds. government
Here is a recipe:
https://building-a-ruin.ghost.io/svb-regulation-bailouts-capitalism/
Alternatively, there are book deals. According to a rough estimate, a high list author can expect between 100K and 1M+ from Harper Collins. Plus extra royalties after N sells. I suppose Matt King Coal counts as one.
Alright, I have listened to the entire podcast.
I still had a couple of questions remaining after listening. I heard the evidence for the wet market as the source – but didn’t hear anything about all the negative testing they did of animals from the wet market. If it originated their from an animal why didn’t they find evidence of that? All they have is the wet market was the geo source. This doesn’t eliminate the possibility that a lab worker infected a wet market worker or brought the virus to the wet market on the way home from work.
I also found their agreement that China was blocking damaging information for both theories – both the wet market and the lab leak interesting. Because China is trying not to admit they have any responsibility – whichever theory it might turn out to be – that leaves both theories plausible.
Finally – the database. All the guests said was that it was complicated and that the database had gone up and down several times. I still think it interesting that the database of genomes studied went down by government action. The lab scientists might have been very open about their work – but only until Sept. 2019, when we have the rumors of the lab workers getting sick and the database went down. Maybe China authorities stepped in and stopped any scientists from further discussing their work. For all we know they did modify a bat coronavirus to make it more transmissible to humans and the virus was taken to the wet market by an infected worker by accident.
Still – the podcast was very interesting and I am glad I listened to it. It does raise more questions and lowered my confidence in the lab leak theory. So I guess I will have to wait and see if China is ever forthcoming or lets the scientists talk more about their work.
I still think Faucci lied about gain-of-function and that it was not good that this research is being paid for by the USA. If it did leak from the lab Faucci is at fault (at least partially) – but if it did originate from the wet market from a natural animal origin than he is off the hook. I would still bet money it was a lab leak – but only $100 USD.
Moshpit, everyone here knows what you are and what you do, you have a very well known conspiracy ideation history. Are you in denial of that very well known history of your own making?
> I would still bet money it was a lab leak – but only $100 USD.
With what odds?
Here are ways to give odds:
https://www.investopedia.com/articles/investing/042115/betting-basics-fractional-decimal-american-moneyline-odds.asp
With fair odds, I might be able to find a counterparty.
I would get the spread, it goes without saying 🙂
why do folks want to investigate the origins of the train crash in OHIO or the failure of SVB?
just forget trumps changes to regulation, clean up the mess and pay off depositers
forward!!!
> forward!!!
This, but un ironically:
Op. cit.
Audits never end.
A so-called scientific controversy is usually handled in the well respected scientific literature.
Playing political theater is just that, political theater. That is something that deals directly with the people. Whereas science, not so much, for mostly good reasons.
Forward is actually a very good proposition, as several others here have already suggested.
I would not have had a clue this was still going on until this post. I actually don’t care at all about something that appears to be unsolvable given the nature of China AND the USA.
Oh and Ridley is a toad wanker.
Steven,
You say this with such confidence.
It’s maybe interesting that there is some current Twitter discussion (search for Ryan Maue, if interested) about how there is a huge overlap between “misinformation experts in the climate and pandemic (lab leak denier) space.” Similar to the argument I was making at the end of the post, but with a very different target. Of course, the “misinformation experts” being highlighted by Ryan haven’t actually been misinforming.
Richard, because the FBI (domestic US security) and the Energy Department (well, duh, energy) are such subject-matter experts…
Sounds like Faucci (sic) is the Michael Mann of Covid origin
Now if only NASA hadn’t faked the Moon landings.
It would have made it so much easier to bring contrarians over to the side of reality.
Classic forensics origin story is the Challenger explosion. It had whistleblowers, evil smaller companies that were railroaded by evil larger companies, Richard Feynman, lowly O-rings, Florida weather, etc.
And they likely still don’t know what caused it. There were significant modifications made to the launch platform prior to the next mission. But someone had to be blamed in the end.
By comparison an easy origin story is the Intel floating-point bug. Cut-and-dried.
And the Darwin Award goes to –
https://www.vice.com/en/article/z3mb89/ivermectin-danny-lemoi-death
Since Uncle Buck did not leave any children of his own, the Darwin Award is real.
Sensible set of heuristics. Another heuristic: People that can say things like “I certainly have no relevant expertise in this context.” are more reliable that people that evidently have even less expertise but can’t bring themselves to say so. Likewise people that can admit their errors and correct them are more reliable that people who cannot envisage themselves making mistakes.
OK –
I am not going to waste another day on Climateball replay after Climateball replay.
I would rather spend it watching real Climateball replays.
Hi Folks,
I joined the Sierra Club in 1971, and have been aware of multiple
environmental issues for many years. A significant part of my
adult life has been about reducing my footprint on Earth,
in particular with respect to fossil Carbon.
My politics have a USA ‘liberal’ lean.
I’m modestly well read on climate change and from what I know, the
arguments that it is real and human-caused make complete sense.
I’m also fairly well read on the whole pandemonium and,
from what I currently know, would say this is a human-manipulated virus.
I know multiple climate-aware folks who see this similarly.
Just because an individual doesn’t accurately understand
climate change does not mean they see covid inaccurately.
Or flip that around:
Just because an individual accurately understands
climate change, does not mean they see covid accurately.
Please be very careful about lumping and labeling people.
Thanks and good health, Weogo
This comment –
> More recently, both the FBI and the Energy Department believe the lab leak is most likely.
Is a classic. Perhaps there’s no better window into the parallels between the climate wars and the origin wars – where Richard leaves out obviously critical information in his characterization of what the DOE and FBI “believe.”
Likewise this comment:
1. collecting batshit from the hinterlands of china and returning it to high population areas for “work” in a BSL2 lab
is suboptimal.
2. the Predict program was a bad idea regardless
three facts stick out
1. there were cases in september, not associated with the market
2. the labs control was turned over to the military in september
3. then the lab had contractors in to————————–
refurbish and replace the ventelation system.
Classic.
Leaves out relevant information so as to stitch together are reverse engineering of events which have an number of explanations and which might or might not be completely concidental.
I’m old enough to remember when Stephen used the exact same “heuristics” and epistemological practices. The more interesting question for me is whether he ever stopped, despite his step across the climate change battle line.
From what I’ve seen, the most common logical problem with the LL proponents is that they almost uniformly point out that “the CCP” can’t be trusted in the evidence they’ve made available, and that “China is lying” to hide the existence of a lab leak.
Two obvious problems there, again problems that directly reflect the kinds of patterns we’ve seen with climate change.
The first is that there are many individual scientists involved when “the CCP” and “China” is being characterized. Saying that “China is lying” actually means accusing specific scientists of lying – and actually not even just Chinese scientists, but scientists of many different nationalities.
The second is a typical selectivity in logic. To the extent that the CCP” is lying about a lab leak (please don’t think I’m saying that all the evidence being provided by Chinese scientists is either fully accurate or that all relevant evidence has been released), they would also likely be lying about any evidence that would implicate the lucrative wild animal trade and the existence of the many, many wet markets throughout China.
Anders –
I think that one of the interesting parallels with the climate wars and the origin wars (not to mention the “lockdown” wars and the vaccine wars), is the whole aspect of “conspiracy theories.”
It’s instructive how often, if I point out that someone is advancing a conspiracy theory, they conclude that I’m only doing so to “shut down the discussion” – even though I’m doing so in the middle of engaging in a discussion.
Not to say that there couldn’t be en element of “shutting down the discussion” by raising the issue of conspiracy theories.
But pointing out that someone advancing a theory that a bunch of scientists across a diverse set of entities are colluding to lie and hide relevant information regarding the deaths of tens of millions of people and illness among countless more, with nary a whistleblower providing evidence of such a collusion, is actually advancing a theory that involves a conspiracy, is relevant part of the discussion.
How often have I been told that if I pose a skeptical question to “skeptics” that I’m trying to “shut the conversation down” rather than trying to engage “skeptics” with skepticism?
A lot of times.
I see a strong parallel.
Steven not Stephen
Anders –
> I may, of course, be wrong and maybe this consensus isn’t very strong. So, maybe we should wait a bit longer before commenting, but I’m certainly not trying to express some kind of view that is at odds with the current view of experts.
Personally, I think it’s too early to try to make a “consensus”-based assessment. It’s so early in the game…. My understanding is that dispositive evidence re the evolution of HIV too decades to surface.
IMO, there seems to be insufficient evidence thus far – at least with respect to the question of whether there might have been a lab-mediated release of a natural spillover (as there might be more of a consensus that SC0V-2 does not have the structure of what would likely be an engineered virus, or at least not the structure of a virus that would have been engineered from any previously documented research).
A more difficult question, imo, is whether there could ever really be a “consensus” view on whether the virus was engineered from undocumented previous research? Perhaps the only way such a “consensus” could be reached is if there were dispositive evidence that the structure could never have been engineered – but in my understanding of what virologists say, that doesn’t seem to be anything near a consensus and I can’t imagine how dispositive evidence in that regard could surface.
I think it’s important to note there that Chinese scientists are generally under a lot of pressure to publish significant research findings in prestigious journals, and thus it may not be likely that if a precursor virus had been developed, it wouldn’t have been documented. Of course, that doesn’t answer the question of whether it was developed in super secret and scary research, just as it doesn’t answer the questions of whether the government is hiding information about UFOs and bigfoot
One might wonder how previous epidemics and plagues spread around the world without a lab in China carrying out gain of function procedures to release a pathogen which would preferentially affect the US and the UK which had some of the highest death rates. (-/s)
It’s all so beautiful:
> The only reason to take that down was to hide the fact that fact that they were indeed working on a virus which was close to or even identical to the Wuhan virus. If not, why take it down?
I love it when logical fallacies jump out so starkly
> Once we get that data (if we ever do) I bet it shows the furin cleavage site, which is what made the bat virus transmissible to humans, was in a lab virus and in fact the virus was manufactured in the lab for gain of function purposes.
A technical opinion formed with, obviously, not suffienet technical understanding
> The emails show that a bunch of “experts” thought the lab leak was the most likely source, but Faucci leaned on them and got them all to support his view and then quickly published a paper to put forward the wet market theory.
An opinion formed about a conclusive but non-technical fact, despite a sufficient basis of knowledge. There’s absolute zero actual evidence that Fauci “leaned on them and got them all to support his view.” The amount of arrogance required to make that statement is quite astonishing. But actually falls short of the even more arrogant version- where people assert with absolute confidence that he “got them to support his view” by virtue of research funding – a version that would have required a time machine as the research funding was approved prior to the event in question.
> China knows the answer to this question and the fact that they are not helping with finding out what really happened tells us all we need to know about how this happened.
This is the best part. He knows all the needs to know about how this happened because of a phenomenon which actually could arise from many different explanations.
> So it is ok to speculate about this.
It’s ok to speculate about something where nothing else is needed to be known to reach a conclusion.
This is all so perfect.
OK – I know this is too many comments..
But I also want to point out how so much of this is at its root located in one simple (and fallacious) heuristic – appealing to motive.
And that in turn overlaps with my latest, favorite cognitive bias – the fundamental attribution error, which largely is rooted in a lack of “cognitive empathy” (also known as perspective taking).
Good news, everyone:
What the world needs is more gentrification of the attention economy.
Joshua,
Maybe, but my understanding is that the expert view at the momentum is that some kind of natural spillover in the market is more likely than a lab origin. This may be a weak consensus, but it seems to be a consensus nonetheless.
Speaking of experts, perhaps those in the know could help –
Are we still into COVID-is-too-much-like-HIV-to-be-natural territory?
If not, where are we on that front?
Anders –
It doesn’t seem to me that the question of whether there could have been a lab-mediated spillover event would really be a matter of scientific consensus.
Even if there is a consensus that SCoV-2 isn’t likely engineered, it wouldn’t really inform that probability.
We could maybe say it seems unlikely a “human vector” (my term) spread at the HWM would have taken place, maybe somehow through genomic data?
We could say it seems unlikely that SCoV-2 was ever the subject of research at WIV without it being documented, but is that really a subject informed by scientific consensus?
Now that I think about it…
Maybe it would be possible to mathematically analyze the probability hat a lab-mediated spillover would occur centered around the HWM as compared to the WIV, and this reach a scientific consensus, and for all I know maybe Worobey or Pekar did that on the depths of their analysis.
Joshua,
The papers seem to argue that the epicentre was the HWM. They also argue that there were actually two spillover events at the HWM and that these involved very slightly different variants, which they then argue makes some kind of association with the lab less likely.
Of course, you’re probably right that we can’t rule out that the origin was the lab but that the spreading occured in the HWM, but my impression is still that those who are experts who have looked at this regards this as less likely than an animal to human spillover at the HWM. Admittedly, this is probably difficult to demonstrate in some definitve way.
Yeah. As I thought about it more, i realized that prolly Pekar and Worobey directly addressed the probabilities of a human-mediated spillover at the lab, by looking at geo-location data related to people working at the lab (compared to geo-location data related to the market).
I guess it seems somewhat unlikely that someone infected by spillover at the lab would travel in a hermetically sealed Uber to the market and then spread SCoV-2 there. What’s the probability that if there were a human vector (my term), there wouldn’t be a signal around that person’s travel at locations other than the HWM? I think that’s basically what they did in their analysis!
And yes, the two-spillover aspect would seem to me to mitigate against a lab-mediated spillover.
Musk = shitposts 😀
Joshua,
As I understand, they also found samples of coronavirus in parts of market that supposedly had the type of animals that could carry it. I guess none of it is definitive, but my sense is that the expert view is that this all points more towards a natural spillover at the market, rather than something associated with the lab.
The other point that I mentioned in the post is that the properties of the virus is that you would expect it to start spreading in an urban area rather than a rural area. If you then consider all the urban areas where this could happen, Wuhan is amongst those where you might expect it to happen and many of the others also host labs that could be – in retrospective – be seen as coincidental. In other words, that it started in a big city that happens to host a lab that studies coronaviruses is maybe not as surprising as one might at first think.
> The other point that I mentioned in the post is that the properties of the virus is that you would expect it to start spreading in an urban area rather than a rural area. If you then consider all the urban areas where this could happen, Wuhan is amongst those where you might expect it to happen and many of the others also host labs that could be – in retrospective – be seen as coincidental. In other words, that it started in a big city that happens to host a lab that studies coronaviruses is maybe not as surprising as one might at first think.
Sure. It’s funny how the whole “too much coincidence for it not to have been the lab” ignores that it’s also “too much coincidence to not have been the market!”
One of those ubiquitous and strikingly selective lines of reasoning that overlaps with a lack of understanding and the power of motivated reasoning.
There’s also the fact that they found nothing in the samples released before the epidemic, including by the main Chinese researcher targeted by our Covid auditors.
I mean, it’d be really odd if, after having spent years on emails and stuff, they do not find some “trick” or “delete.” But perhaps this time we should count the number of swings and misses…
There is a very deadly pathogen trying to infect this very thread! It is of human origins. That much we do know with absolute certainty.
Are ninjas human, Everett?
Asking for a ninja friend.
weogo,
Yes, this is certainly true. I would argue, though, that it’s fine to take what some have been willing to promote in the past when judging what they promote today. It doesn’t mean that just because they were wrong in the past that they’re wrong now, but it is a bit of a red flag. I would also add that if some groups regularly go against expert opinion that that might also be a red flag. Again, doesn’t mean they’re wrong, but does suggest some caution should be taken.
Willard: the late Uncle Buck’s Fox protege’ is still on the horse paste case:
https://vvattsupwiththat.blogspot.com/2021/08/cures-pigeon-lice-horse-worms-so-why.html
The conflicting reports might make you start to wonder if ninjas were real. The short answer is yes, and they still exist today, but their origins might be a little different from your imagination. Let’s go over some of your burning questions about ninjas and where to see them on your next trip to Japan.
https://alljapantours.com/japan/travel/where-to-go/where-are-the-ninjas-travel-japan/
But rumors have it that HWM/WIV are but two places thought to have started this most recent of invasive species aka homo sapiens ninjitus.
I think the ninja virus predates the Internet, in both senses of the word *predates*.
Bret is one of Chris’ pet conspiracy hypothesizer, Russell. You might like:
https://www.sorryantivaxxer.com/
I’m not saying Bret killed people, but he *did* raise concerns about vaccines:
How dare he tries to exploit Sainte-Céline!
Almost all human diseases are zoonotic. They originate in our close contact with animals then become a pandemic danger when they mutate to be infective between people.
Whatever the origin, the main way of dealing with them is in direct conflict with the requirements of a capitalist system. Free movement of goods and people conflicts with social distancing, masks, gloves and lockdowns with minimal excursions to obtain food, go to work or visit hospitals, care homes, or doctors/dentists.
Sweden had a much higher death rate than Norway. Despite their rapid roll out of the vaccine, both the UK and the US never reached the level of ‘herd immunity’ and paid the price in deaths.
All of these factors would play out if the virus was entirely and intentionally human designed OR if it is another accidental transfer from an animal source next time.
@-“Knowing the origin of COVID-19 is fundamental to helping predict and prevent future pandemics.”
Could anyone explain what difference it makes if a careless lab worker is the source of a pathogen or a careless live animal market trader ?
And why somebody would favour one option over another.
izen,
Indeed, I’d wondered something similar. If it isn’t engineered, then it’s either a careless lab worker or a careless live animal trader. If so, what does this tell us? We should, of course, aim to make lab work as careful as possible, but it’s not something we would want to stop. However, would this substantially reduce the risk of a spillover if live animal traders are still operating as before?
In part of this episode, there’s a good discussion (imo) about lab safety.
https://www.microbe.tv/twiv/twiv-987/
The point being that there are already solid protocols in place. Of course, the discussion is among virologists who obviously think the benefits of studying how pandemics start from viruses is worth investigating.
Clearly, one reason that the there is so much focus on whether SCoV-2 came from a lab or not, is that the issue can be conveniently used for political expediency.
Indeed, we’ve seen evidence of that in this very thread. A lab leaks makes for some high satisfaction hippie-punching.
Imo, the worst aspect of this lab leak proxy ideological battle is that it will have the effect of making it harder to collaborate which Chinese scientists. Perhaps not a great outcome given that there’s so much wildlife trade in China, with animals that may very likely be a source for spillover events.
Also concerning is that the political exploitation of the lab leak possibility may have the effect of distracting from the perhaps higher risk from a relatively unregulated potential source for future pandemics: industrial animal farming that is often conducted in extremely unsanitary conditions (say chicken factories with huge fans that blow potentially dangerous pathogens directly into the surrounding communities).
> what does this tell us?
It tells us that being hardwired for Whodunnit stories does not prepare us for simple solutions:
Source: https://andthentheresphysics.wordpress.com/2021/06/16/how-to-reason-by-analogy/
We know already that animal markets are not a good idea. We would rather deny the security risk and chase Whodunnit rabbit holes instead of revisiting our eating habits.
One of the articles linked in that episode of TWiV:
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease burden with vaccines and antivirals. Despite this long history, the COVID-19 pandemic has brought unprecedented attention to the field of virology. Some of this attention is focused on concern about the safe conduct of research with human pathogens. A small but vocal group of individuals has seized upon these concerns – conflating legitimate questions about safely conducting virus-related research with uncertainties over the origins of SARS-CoV-2. The result has fueled public confusion and, in many instances, ill-informed condemnation of virology. With this article, we seek to promote a return to rational discourse. We explain the use of gain-of-function approaches in science, discuss the possible origins of SARS-CoV-2 and outline current regulatory structures that provide oversight for virological research in the United States. By offering our expertise, we – a broad group of working virologists – seek to aid policy makers in navigating these controversial issues. Balanced, evidence-based discourse is essential to addressing public concern while maintaining and expanding much-needed research in virology.
https://pubmed.ncbi.nlm.nih.gov/36700653/
Also – relatively digestible although still technical:
https://t.co/GfenfOmPxq
“We would rather deny the security risk and chase Whodunnit rabbit holes instead of revisiting our eating habits.”
Wildlife trade is likely the source of SARS-CoV-2
https://www.science.org/doi/10.1126/science.add8384
“The zoonotic origins of the SARS and COVID-19 pandemics are very similar. Both likely involved trading of susceptible live wildlife at local markets and people who work and live in and around these markets. Developing real-time outbreak surveillance systems that are better at predicting risks would need to consider the supply chains at the human-animal interface. For example, wildlife trading for fur, skin, and human food is usually supported by different farm sizes for socio-economic reasons, such as small farms in rural areas in an effort to reduce poverty (9). Wild animals harbor various pathogens, including potentially pandemic-causing coronaviruses, and only a fraction of virus diversity is being sampled (10, 11). Farming large numbers of wildlife inevitably provides opportunities for spillover events and so poses unprecedented threats to human health.
When farmed wildlife population sizes are large [at the scale of tens of millions or even larger (9)] and the underlying infrastructure for zoonosis control is lacking, farmed wild animals become reservoirs for pathogen genetic diversity to accumulate (9, 12). The diversity and scale of wildlife farming make zoonosis control almost impractical. Spillovers are destined to happen, particularly when there are changing driver events, such as altered demand owing to meat or food shortages or because of cost increases (9, 13). For example, since early 2022 there has been increased demand in Thailand for cheaper meat from crocodile, a widely farmed wild animal for its skin, during the African swine fever virus pandemic that resulted in high pig and pork prices (9, 14). Although applying existing livestock regulations to wildlife farming may minimize such risks, its effectiveness remains to be seen (15). When the science underlying multiple-host pathogen evolutionary dynamics is still not fully understood (12), it is challenging to establish effective zoonosis control infrastructure. Although Worobey et al. and Pekar et al. reveal the likely details of early zoonotic and epidemiological events that led to the COVID-19 pandemic, without knowing the exact animal origin of SARS-CoV-2 the threat posed by another similar virus from wildlife farming is looming.”
Good luck trying to convince the people of China (and elsewhere) to change their (live or recently dead) animal buying habits.
Those two Science paper links and Google Scholar references …
https://www.science.org/doi/10.1126/science.abp8715
https://scholar.google.com/scholar?cites=17266377990256089096&as_sdt=5,25&sciodt=0,25&hl=en
https://www.science.org/doi/10.1126/science.abp8337
https://scholar.google.com/scholar?cites=16754621061188843218&as_sdt=5,25&sciodt=0,25&hl=en
Joshua,
Thanks for those two recent scientific links. Very much less thankful for drive by disinformation discourse.
Willard, ATTP:
Can we agree on the utility of getting the Institut Merieux engineers who built the WIV facility to testify, without fear of civil non-disclosure agreement sanctions as to what they make of all this?
Knowing the Origins of COVID-19 Won’t Change Much
https://time.com/6150383/origins-covid-19/
An op-ed so go figure …
“The best way forward may be to minimize the distraction of a politicized attempt to assess origins while, instead, investing in long-term international collaborative endeavors on SARS-CoV-2 and in preparation for future epidemics and pandemics.”
Well said, I might add.
Everett –
I let you know when I start giving a shit what you’re thankful for.
Everett –
This is just for you.
You’re welcome.
Hmm, err, not sure where you are going with whatever you are going with. My previous comment, 2nd sentence was not directed at you personally, but someone else in this thread.
Oh and I could care less what so-called Americans think about, well, most anything these days.
We would rather deny the security risk and chase Whodunnit rabbit holes instead of revisiting our eating habits.”
Wildlife trade is likely the source of SARS-CoV-2
https://www.science.org/doi/10.1126/science.add8384
hey mr virologist do you think the cause is
A. your buddies collecting bats for science OR
B. those peasants in the wet market?
https://www.nationalreview.com/news/wuhan-lab-air-circulation-systems-were-defective-ahead-of-first-known-covid-cases-congressional-report-finds/
2021, Mosh.
How much more odds does that give to the lab leak?
In return:
https://www.texastribune.org/2012/02/07/mccaul-familys-pipeline-holdings-stir-controversy/
> hey mr virologist do you think the cause is
A. your buddies collecting bats for science OR
B. those peasants in the wet market?
I wonder if there’s ever been a study of whether people who engage in a certain kind of behavior are more likely to attribute that behavior to others?
Not to mention saying that peasant in the wet market are to blame might be a tad different than saying the pandemic started with a spillover from wildlife.
In part of this episode, there’s a good discussion (imo) about lab safety.
https://www.microbe.tv/twiv/twiv-987/
The point being that there are already solid protocols in place. Of course, the discussion is among virologists who obviously think the benefits of studying how pandemics start from viruses is worth investigating.
more interesting question is how/why did 3 lab workers go to the hospital in november?
https://www.nbcnews.com/health/health-news/u-s-intel-report-identified-3-wuhan-lab-researchers-who-n1268327
Oh boy, drive bys with links to MSM even, how sciencey of you Moshpit.
2021, Mosh.
How much more odds does that give to the lab leak?
its not a matter of odds.
given the evidence at hand both explainations work
i would say we dont know which theory is correct but we do know the lab leak
is not a conspiracy theory.
if it is then every theory that relies on government mistakes is a conspiracy theory
the question is what evidence would rule out each theory
So proportedly I am now a virologist or some such, when I appear to ask for peer reviewed scientific articles, on stuff that is proportedly sciencey in its nature?
Moshpit ‘chutes into CCP twice in 2019-09 to deliver the American made coronavirus!
> i would say we dont know which theory is correct but we do know the lab leak
is not a conspiracy theory…
What an odd thing to say.
“the” lab leak.
Obviously, that depends on whether “the” lab leak theory linked to a conspiracy theory.
It’s not like it would be even remotely difficult to find many, many lab leak arguments that are explicitly linked to a theory about a conspiracy.
Conspiracies happen and some some conspiracy theories are entirely plausible.
It’s like when people saying the temperature records have been doctored by scientists colluding together get the vapors when you point out they’re a advancing a conspiracy theory.
Actually, as time progresses it does become evermore conspiracy ideation. You can’t say that for the natural origins theory except for those already disposed to conspiracy ideation.
> more interesting question is how/why did 3 lab workers go to the hospital in november?
Maybe they read one of your blog comments and felt nauseated?
> its not a matter of odds.
It actually is a matter of odds. Unless you got some kind of smoking gun, which you don’t. Or you are happy with the hawks playing offense for you no matter what.
As for « lots of theories », it rings a bell:
A certain autocrat did indeed float the lab leak conspiracy way back in January 2020. That autocrat has a nickname. Small Hands. Heck, could be our next POTUS even. It is just what ‘merica deserves. MMGA 2024!
> more interesting question is how/why did 3 lab workers go to the hospital in november?
If only you listened to the podcast, Mosh.
I miss Bender.
From a paper:
Highlights
•
The origin of SARS-CoV-2 is not established, but most papers point out to a zoonotic origin of this coronavirus.
•
An important number of available papers on the origin of SARC-CoV-2 are not experimental studies.
•
The hypothesis of an unnatural origin of SARS-CoV-2 cannot be yet scientifically discarded.
Discarded. Not yet. People are betting the farm on it with low confidence. Lol.
Me, I agree with Roger Frutos, who agrees with my childhood experiences with viruses and livestock. SARS-CoV-2 has no origin.
Now, now Joshua.
You should know from Climateball experience that conspiracy theories don’t require logical coherence or factual consistency. Indeed they thrive on the lack thereof. It’s a feature not a bug.
Steven,
Except it does seem that you’re implying some kind of conspiracy to cover things up.
If it involves some kind of intentional cover up, then it probably is.
Steven, with the discussion of odds this would seem to be the perfect case for a Bayesian approach.
The prior for someone who co-authored a cherry-picked, misrepresented and fundamentally untrue conspiracy theory that slandered honest, hard-working scientists for profit, based on stolen goods to boot, is, ahem, somewhat challenged when it comes to identifying and screening out other conspiracy theories.
The posterior odds are that whoever else might be right, you’re very probably wrong.
Sorry, but you lie in the bed you make. And are still making.
I’ll entertain several conspiracy theories at once. The main one is political expediency in ‘merica circa 2024 elections.
This does not bode well for the 2015 Paris Accords. 😦
China’s Loongson Faces Overwhelming Obstacles Due to U.S. Restrictions
New US Sanctions Against China’s Chip Sector May Set it Back by a Decade
“After the U.S. government imposed sweeping sanctions against the Chinese chip sector that blocked access of the country’s semiconductor champion SMIC to wafer fab equipment that could be used to make chips using 14nm nodes and below, it started to work on even stricter limitations. By now, the U.S. government is ready to expand its sanctions and this time it will make sure they are supported by Japan and the Netherlands. Once the new sanctions are imposed, the Chinese semiconductor sector will be set back by at least 10 years.
The U.S. is looking to limit access of Chinese chipmakers to wafer fab equipment that can be used to make chips on 40nm-class process technologies and below, reports DigiTimes, citing industry sources. If all the restrictions are imposed and no export licenses to sell advanced chipmaking tools to SMIC and other Chinese chipmakers are granted, this will set back the People’s Republic’s semiconductor industry by at least a decade. Yet, it will also hurt the wafer fab equipment (WFE) manufacturers, which could have an impact on the whole industry.
Speaking of hurting WFE manufacturers, it looks like ASML, the world’s leading maker of lithography equipment, will be hurt less than its American and Japanese counterparts. Export restrictions announced by the Dutch government last week will bar shipments of ASML’s Twinscan NXT:2000i, NXT:2050i and NXT:2100i scanners, the company’s most sophisticated deep ultraviolet (DUV) lithography tools, Bloomberg reports. By contrast, about 17 chipmaking tools produced by U.S.-based manufacturers require an export license from the U.S. Department of Commerce, according to Bloomberg. With new restrictions, that number will double, the report claims, which will naturally hurt businesses like Applied Materials, KLA, and Lam Research.
Meanwhile, if China wants to make its semiconductor industry self-sufficient and adopt advanced production nodes, it will have to ensure that its fab tools producers — such as AMEC (lithography), Kingsemi (etching, deposition), and Naura (etching) — are on par with their American and European rivals. This is something that will take years, as the most advanced scanners that AMEC has can only produce ICs on a 90nm-class node, a technology used to make CPUs in the early 2000s.
If SMIC loses its ability to produce chips on 28nm, 14nm/12nm, and more advanced fabrication processes, hundreds of Chinese chip designers will have to outsource production to companies like TSMC, UMC, GlobalFoundries, and Vanguard. This will certainly be good for these contract chip manufacturers, but it will be disastrous for SMIC in particular and for the Chinese semiconductor industry in general. And that appears to be the intent of the sanctions.”
https://www.tomshardware.com/news/new-us-sanctions-against-china-chip-sector-may-set-it-back-by-decade
The Biden administration is the one imposing sanctions now. They took our jobs!
The D’s are scared shitless, I know this because I get like ten emails a day from them begging for money. Toot Toot, the Trump Train, it be moving, dragging both parties behind it!
https://en.wikipedia.org/wiki/It%27s_the_economy,_stupid
Since he has been mentioned earlier:
https://www.theguardian.com/world/2023/mar/15/ho-wan-kwok-arrest-fraud-conspiracy-steve-bannon
It is now easier to believe that he is a friend of teh Donald.
Before enquiries, equities:
https://www.commondreams.org/news/2022/02/01/amid-push-ban-lawmakers-traded-355-million-stock-2021
Imagine if Freedom Fighters really cared about public trust in government.
Conspiracy theory? What conspiracy theory? Did they actually use the words “conspiracy theory?”
Putting Rand Paul in evidence is a truly negative activity. Remember any message cited is a promotion of that message, and when the message is obnoxious lies, that’s not helping. Aaron Rupar is annoying that way.
Yeah, and the lab-leak hypothesis is a conspiracy theory. There is not one single spec of actual evidence for it. Just get to the end. The intelligence community does not have a fucking thing that supports the lab-leak theory. The only dream they have it. The virology community uses the spillover model, which cannot find the origin of its nose. Viruses circulate and evolve. Real fast. Use the circulation model. The virus likely circulated in the very remote, mountainous region of Laos that is adjacent to China. China has been building a railroad there. Thousands of Chinese workers traipsing from their homes from all over China, mostly by rail, to build bridges, rail beds, and tunnels in remote bat cave world. Back and forth, Back and forth. Some in helicopters. Fast. Then some knuckleheads in the USA who hate gain-of-function research come up with the lab-leak hypothesis to end gain-of-function research. Which is the end of scientific progress (except, the Chinese are going to keep right on doing it because it’s point-blank stupid to not do it. They can engineer a virus and kill all the capitalists!) The enemies of gain-of-function research actually claim ending gain-of-function research will prevent the next pandemic because this one was caused by a lab leak. Sorry. That is hilarious. Nature is constantly doing gain-(and loss)-of-function research on potential pandemic viruses at the freaking speed of light. We are totally insignificant in that math.
Then the people who have Pavlov’s dog syndrome when the word China is ever mentioned glommed on: balloons. Tik Tok. Engineered viruses. Farmland by Fargo.
Susan –
> Remember any message cited is a promotion of that message,…
Maybe in theory but I don’t think it really matters in context. If he’s on Fox News, putting out that tweet won’t meaningfully dampen the effect but neither do I think it will materially amplify it.
Anyway, kind of a gallows humor to laugh at the faux defense of conspiracy mongering.
Can’t speak to Rupar more generally as I wouldn’t know.
Joshua, yes, sort of, but still … Some people I respect have made this point more forcefully recently, and Willard responded with a useful Wikipedia entry on rage farming. I get posts from Aaron Rupar on Twitter (don’t do posts, but the info, particularly on climate/weather is good, and some of the black humor helps with surviving these dark times): he does it a lot. I am so tired of having links spread from horrible people doing bad stuff. If I never saw their horrid mugs again it would be too soon (tfg, mtg, Boebert, and a good few others). But making it clickable helps them, so I’m on a tear about it. There are so many of them, and I can’t help feeling if we starved them of our attention it might help.
I’m open to the idea that Covid might have had an element of spreading from labs, but the QGOP is bent on saying it was created there (gain of function). That was what made me so furious about the attack on Dr. Fauci, who has been so patient and good about the evil abroad in the land, doing what he can to help, despite death threats to his family and such (the new normal: if you can’t win, hate and get violent). In Boston I saw first hand the Biogen international conference in the early days. We used to work with them (CRO) and that health professionals would be hugging and sharing food – I don’t know how many thousands cases came from that one Boston conference (which spread around the world, it was a health care pow-wow). Covid was in the news and people are so stupid about the spread of colds and such, such a simple thing to understand and relatively easy to prevent.
I don’t like it when people I identify with do bad things: that goes triple for Biden at the moment; he’s done three unnecessary bad things he promised not to in the last few days. We need better choices, and a stronger sense of reality.
Susan –
> I am so tired of having links spread from horrible people doing bad stuff.
Ok. I’m with you on that.
I got annoyed with the pretense that the conspiracy mongering isn’t real and pernicious – only making it harder to address the real issues associated with addressing the security concerns with research and pandemics, irrespective of but including whether this virus was engineered, spread through a lab-mediated leak, or from a straight spillover event.
I call it outrage mining. I suppose it’s like a sugar high – a short term sense of some kind of victory but in the long run it only contributes to partisan bickering where we hate on each other and get distracted from the real underlying problems.
It’s easy to fall into the trap of thinking that individual contributions don’t matter much in the long run, but clearly the juvenile point scoring and end zone dancing does scale up.
Related:
I find the style obnoxious – kind of shock jockeyish. But they’re talking about something that really is pernicious conspiracy-mongering.
“given the evidence at hand both explainations work”
True, but if it is a careless lab worker then that implies a tightening of precautions and regulations if not just closing a very small number of institutions.
If it is a careless live animal market trader that would require the strict regulation or abandonment of a large sector of the social food system. This would result in the loss of more money and undercut the social standing of the Chinese government.
If you a pragmatic member of the CCP which would you choose? Closing a few virology labs, or closing all the live animal food markets.
However the recent finding of dog raccoons sold in the market as the possible vector animal makes such a choice a little more difficult.
You mean this, izen?
Lots of theories.
This is also an interesting discussion.
Bah. Just virologists talking.
As always, when people accused of conspiring together deny that they’re conspiring its just evidence of the conspiracy.
“absolutely unhinged process known as astroturfing” [though topic oil & gas, not Covid, the methodology is all too common]
Too many people don’t know how well organized these lies are.
My point is that there is a good motivation for this conspiracy.
If it was the intentional manufacture of a virus with ‘added function’ in a Chinese lab that was then ‘accidentally’ released it gives those in the West with an anti-oriental and anti-expert bias a chance to blame the Chinese government with collusion with Fauci and the CDC/NIH.
And it would give China an easy option of closing the few labs capable of such work with the loss of jobs of just a handful of researchers.
Only the scientific knowledge to predict and prevent future epidemics would be lost. No harm would be felt in the present.
Much better than having to outlaw wet markets in Nations with such institutions still having a significant role in selling people food.
Despite the large amount of historical and current evidence that such close contact between many different species and humans was the usual way such disease pandemics affect human society
Izen, the problems in the US are much closer to home. “Lock ’em up” excuses. Anti-mask, anti-precautions, outlawing vaccinations, making it illegal for doctors to dispense legitimate treatment, this is becoming all too common. It turns out it’s really easy and popular to gin up hate and blame. Community, what’s that? Socialism! (Never mind that, for example, Jesus was the ultimate woke socialist, for those who call themselves Christian.) Since collective action is our only hope, it’s hard to watch the antics: in the UK you have Sunak and the legion of horrors now in charge.
It’s become hard to defend reality and the truth, which seems beyond belief to me.
@-SA
Whatever your beliefs; Nature, (truth, reality) bats last.
Denying healthcare and social justice is inherently self-harming. Covid has killed a significantly higher number of right-wing cultists because of their beliefs.
Even when a irrational belief becomes the dominant social zeitgeist as with Fascism in 1930s Italy, Japan and Germany, the internal contradictions lead to its eventual downfall.
Unfortunately a lot of people, including those with no adherence to irrationality die and suffer along the way.
But that is the human condition, and probably the best argument against the existence of a benign supreme supernatural entity overseeing it all.
Some people are casting doubt on the data used to show Raccoon dogs where the source of virus:
https://www.dailymail.co.uk/news/article-11872527/Experts-pour-scorn-Chinese-data-suggesting-RACCOON-DOGS-responsible-COVID.html
Alleged that same data previously used to show virus did not originate from wet market. Also data deleted, so now not available.
Izen –
It seems maybe you think I didn’t get your point? Most assuredly I did.
Your point was clear.
China’s lack of transparency here is a baseline condition.
It’s a feature of the lab leak conspiracy theories to turn to that baseline condition as “evidence” for a lab leak. They can simply say that China’s lack of transparency means China’s trying to hide a lab leak.
In such a manner, they can ignore that China’s lack of transparency is a baseline condition, just as they can ignore any reasons China might have for wanting to hide a wet market-mediated spillover event.
It’s the mark of a conspiracy theorist to use whatever logic they might want to use to “prove” the conspiracy. In this case, it matters not that there could be any number of reasons for China to be not transparent, just as it doesn’t matter that China’s lack of transparency in these matters long predates the beginning of the pandemic.
And having a vehicle for politically expedient China-bashing is icing on the cake.
This is beautiful.
> But Dr Stephen Quay, a pharmaceutical CEO who has studied the origins of covid, likened publishing research that relies on data that’s no longer available to using evidence that doesn’t exist ‘in a court of law’.
The Daily Mail using a “BIG PHARMA” exec as a reference on COVID.
Even better:
https://en.wikipedia.org/wiki/Li-Meng_Yan
Guo Wengui has been mentioned before.
Imagine if Junior wrote six months of Substack posts on that kind of conflict of interest.
Solving today’s modern challenges in breast health and the coronavirus pandemic:
https://drquay.com/
Scientist. Author. Entrepreneur.
If you look at his tweets, you get to André Goffinet, Scott Ferguson, Matt King Coal, Alina Chan, Alex Washburn and tutti quanti.
The usual crew.
From https://www.science.org/content/article/covid-19-origins-missing-sequences:
“Gao’s team used swabs to collect environmental samples from many of the stalls of the Huanan market between 1 January 2020, the day it was shut down, and 2 March 2020. The group reported last year that some of the samples that tested positive for SARS-CoV-2 also had human genetic material, but no DNA from other animals. The team concluded in a preprint posted on Research Square on 25 February 2022 that this “highly suggests” humans brought the virus to the market; Gao and his co-authors said this meant the marketplace was not the origin of the pandemic but simply amplified early spread of SARS-CoV-2.”
I thought the pandemic started in 2019? So the Raccoon dog swaps were taken in 2020. Hmmm.
I can’t bring myself to do long videos or podcasts: I fritter away enough time on the internet already. But here’s an excellent short factfest on Guo, only 6 minutes! A parade of villains. Covid conspiracy promo at 3:30.
@-J
“It seems maybe you think I didn’t get your point? Most assuredly I did.”
I expected you would.
My point was directed mainly at Mosher, who I suspect thinks he is exposing the inherent corruption of Chinese governence, construction or whatever.
Really he is just a useful idiot for the Chinese government who clearly do not want absolute proof that the wet market is the source.
He has also shown his propensity to assume malicious human action when benign confusion of system function is a better and more coherent explanation.
Richard,
Why is this an issue? They are suggesting that they’ve found samples associated with animals in the place where the spillover events are thought to occur.
ATTP:
Well – if the pandemic was raging in Wuhan (lockdown started Jan. 23, 2020) then a lot of virus was already around. It could have come from people touching the cages or coughing on the cages – right? Is it a spillover event if it is found 3 months after the pandemic started (maybe as early as Sept. 2019, and certainly by Nov. 2019). I am not an expert, but it would be better evidence if they found virus in an animal before Nov. 2019 at the wet market, not on a cage after the pandemic is raging. As far as I know not a single animal tested positive for COVID-19 (and they tested over 50,000 animals), which is why we are looking at virus on surfaces and not in animals.
Just one person’s opinion.
Here’s a theory.
Since SARS if not before, we know that wet markets can be potentially virus hubs. Chinese authorities know this. If COVID happen to emerge like that, it would be seen as a policy failure.
However, that’s better than the possibility that they fabricated bio weapons.
But now that bio weapons are more or less a certainty thanks to Freedom Fighters at Elon’s led by a gal from Singapore, they try to cut their losses.
Hmmm. Big hmmm.
Richard,
Yes, finding it in animals earlier would have been stronger evidence, but it at least suggests that it was present in animals at the location where the virus is thought to have started spreading.
There is probably unlikely to be any single bit of evidence that determines the origin, but theres lots of evidence that points towards a spillover event in the market and very little (if any) that actually points towards a lab leak.
Willard:
Sure. China was trying to deflect from either China source theory, and if that is no longer possible, they fall back on the least offensive China origin. Maybe. I am not sure which is the least offensive to China. I was not aware bio weapons were now a certainty. Can you link to what you are referring to?
I am still assuming IF the virus leaked from the lab, it was inadvertent and the research was directed and paid for by the USA (gain-of-function on bat coronavirus), then something sloppy happened in Sept. 2019 (which is when China deleted the database of genomes, changed the ventilation and the lab was taken over by the military).
ATTP:
I thought they sampled many if not all the animals at the wet market – and found nothing. So if virus is on the cage and it is mixed in with human dna and raccooon dog dna – BUT the raccoon dog tested negative and there are many people running around who tested positive – doesn’t that point toward a human origin?
RickA,
I thought we already covered that theory. To find two strands in the market would be very odd if it came from the lab. Like, very odd.
How much odds did you put in the lab leak theory again? I hope it is more than 50-50. Otherwise I would have to conclude two things. First, you like to gamble 100 bucks. Second, you are not that confident in your belief.
Also, I do not think a lab leak that is not from a bio weapon facility would make China [not] look worse. On the contrary, in fact. Hence why they denied that the wet markets existed.
Richard,
I’m not sure what you’re referring to, but my understanding is that the latest results suggesting a link between raccoon dogs and the virus is a reanalysis of samples that had originally been claimed to contain no animal DNA. That original paper has, AFAIA, been strongly criticised by other scientists.
I’m not sure it actually matters much either way. Both Zoonotic and lab escape remain a risk into the future and both should be controlled in our own facilities and environment; we have zero direct influence on how well China controls either.
We also lack sufficient evidence to have a strong conclusion on likelihood IMO.
My prior says that whichever side of the argument Ridley is on is likely to be incorrect.
“more interesting question is how/why did 3 lab workers go to the hospital in november?”
LOL. I visited Shanghai that October.
A work colleague had his wife hospitalised due to pneumonia at the time.
I went down with an awful respiratory bug on my return.
“Interesting” ???
“Describe confirmation bias using covid origin theories as an example”
Confirmation bias is a cognitive bias that involves favoring information that confirms one’s preexisting beliefs or values while ignoring or discounting information that contradicts them. Essentially, people tend to seek out and interpret information in a way that supports their existing views, while disregarding evidence that challenges those views.
One example of how confirmation bias can manifest in current events is in the debate surrounding the origin of COVID-19. There are several theories about how the virus first emerged, including the possibility that it originated from a lab leak in Wuhan, China, or that it crossed over to humans from animals in a wet market in the same city.
People who believe in one particular theory may be more likely to seek out information that supports their view, and discount information that challenges it. For example, someone who believes the lab leak theory may be more likely to pay attention to reports of safety concerns at the Wuhan Institute of Virology, while ignoring evidence that suggests the virus may have originated from animal-to-human transmission.
Similarly, someone who believes the wet market theory may be more likely to focus on evidence that suggests the virus was present in animals at the market, while discounting reports of early cases of COVID-19 in people who had no connection to the market.
In both cases, people are exhibiting confirmation bias by seeking out and interpreting information in a way that supports their existing beliefs about the origin of COVID-19. This bias can make it difficult for people to objectively evaluate evidence and may contribute to the polarization of opinions surrounding the pandemic.
vtg, otoh, endlessly spinning this argument is a way to feel like we’re doing something. Finding somebody to blame excuses us from facing reality while that’s going on. What we could do is look forward and act on behalf of humanity.
> ; we have zero direct influence on how well China controls either.
I don’t think that’s quite true. Collaboration is probably the best way to maximize safety going forward. China-bashing is probably sub-optimal in that regard. Of course, distinguishing between China-bashing and expecting/recognizing accountability can be tricky.
Willard:
Given the samples were collected from Jan. 1, 2020 to March 2020, isn’t it possible that the virus mutated in humans and the different strains were passed from humans to cages and surfaces at the wet market? After all, lineage B was detected in humans on Dec. 24, 2019 and lineage A was detected in humans on Dec. 30, 2019, so we know it was present in humans before the sampling took place at the wet market. Why assume two separate spillover events when we know the virus mutates so rapidly in humans? Which is the simpler explanation?
I am not an expert, but it seems to me that if lots of humans were running around Wuhan with A and B strains in Dec. 2019, couldn’t they have passed virus to cages and surfaces at the wet market over a 2 or 3 month period in 2020, while the pandemic raged in Wuhan?
Richard –
Am I right that you disagee with the analyses that shows early infections were overwhelmingly associated with the market, and not the lab?
If so, what is your basis for that disagreement?
Joshua:
No. I accept the data that the early infections clustered around the wet market. I just don’t think that rules out the lab leak. Why is it more likely that two separate spillover events occurred at the wet market than that a sick lab worker went to the market for lunch, infected a wet market worker, the virus mutated and humans at the wet market with A and B viruses passed virus to cages and surfaces during Jan. 1 2020 to March 2020?
Given the three events at the lab in Sept. 2019 (database genomes deleted, ventilation changed and military takeover) it seems like something happened at the lab – so I think it more likely that the lab was the origin of the virus and it went to the wet market. But of course, it is possible there were two separate spillover events at the same market, as has been suggested.
My razor (and maybe Occam’s) says when the government is paying to modify a bat coronavirus to make it easier for human to human transmission – when it starts transmitting among humans I look to that activity as the origin. That is my bias. Plus the government cover-up at the lab plus the Faucci lying about gain-of-function research. It all smells pretty bad to me.
I hope we do find out one way or the other though. It seems pretty important to stop whichever bad activity started this – either animal markets or dangerous research at labs. Didn’t SARS escape a lab also? Why not COVID also?
———- Forwarded message ———
From: Joshua Brooks
Date: Fri, Mar 17, 2023, 5:05 PM
Subject: J
To: Joshua Brooks
Richard –
> I just don’t think that rules out the lab leak…
From what I’ve seen, not very many people say that a lab leak is “ruled out,” although Worobey et al. do seem to argue that evidence of the market as the center of the initial outbreak is “dispositive.”
> Why is it more likely that two separate spillover events occurred at the wet market than that a sick lab worker went to the market for lunch, infected a wet market worker,….
I’m confused by your question. If it were a lab worker who was “patient zero, ” wouldn’t it stand to reason that lab worker would have infected other lab workers he/she worked with on a daily basis, and his/her family, and the families of his/her fellow lab workers, all leading to a significant signal of infection associated with the lab, even if said “patent zero” had lunch at the market while infected. And keep in mind the market isn’t anywhere near the most crowded place or largest place in Wuhan. So I’d imagine the probabilities that a worker would go to the the single place where a natural spillover event would take place, and the evidence would show up not just anywhere in the market but the part of the market wmmhwre the wildlife trase takes place, must enter into their analysis.
> infected a wet market worker, the virus mutated and humans at the wet market with A and B viruses passed virus to cages and surfaces during Jan. 1 2020 to March 2020?
I haven’t dug into the the depths of the Worobey and Pekar papers, but my understanding is that the answers to your questions lie there, from their perspective, and it has to do with the time lines and sequence of which strain came first and other technical details such as (from what I understand) no intermediate strains hacking been found. Have you read their papers? It seems they go onto a great deal of detail as to the science of their analysis, in the appendices and the like. I think if you aren’t inclined to just take their word for it that they’ve provided answers these questions, maybe you should look at their analyses to see if they answer your questions and whether you find their answers satisfactory? I’d say that the chances are that it’s unlikely you’re going to come up with some critical flaws in their analysis, that strike you as fairly obvious questions, given that they have analyzed these issues in depth from a perspective of deep experience and domain specific knowledge.
That doesn’t mean, of course, that or couldn’t happen. Perhaps you might even reach out to them to ask for clarification.
Likewise for your other questions related to events at the lab. Do you think it’s particularly uncommon for people who work in a lab to contract respiratory diseases? Apparently in Wuhan it’ it at all unlikely for someone with a respiratory I’ll was to go to the hospital to acquire primary care. Sea to me all of your questions are emedded in a great deal of uncertainty and could well have explanations that don’t support a conclusion of a lab leak. I’d say it’s a mistake to speculate that they do without context-specific knowledge.
Joshua: RA earlier in this thread does a simple “logic” progression that accuses Dr. Fauci of murdering 7 million people. Trying to reason with him is a waste of effort.
Susan –
I would think if Richard has all these questions he should certainly investigate whether people who have actually researched these issues have answers to his questions before he assumes Fauci is guilty of hiding the cause of tens of millions of murders.
It’s not about reasoning with him, really. It’s more just a way for me to become familiar with the issues at hand.
RickA,
I asked for odds. You still haven’t given me odds. You are Just Asking Questions instead.
I find it odd.
Just my opinion.
There seems to be a parallel between Xi’s people dismissing the lab , and blaming the fauna, and Brezhnev’s blaming the 1979 anthrax episode on careless Siberian shepard’s instead of Sverdlovsk’s Soviet Army CBW lab .
Both discourses of denial overlap the Climateball playing field.
Such as the regional scare that years after, I told Mat Meselson , who’d been on the Sverlovsk case, I was going to now- Ekaterinberg on unrelated arms control business, and he told me to take along some cipro , just in case.
SARS-2 might be more like SARS-1 than anthrax, Russell.
Just my opinion.
Nothing can rule out a lab leak. From any lab in any city in the world that does research on coronaviruses that has an airport within a few hours drive of the lab.
Russell
>Xi’s people dismissing the lab and blaming the fauna?”
Huh? What are you talking about?
JCH,
That is my theory to. In the run up to the 2020 elections, the D’s got Fauci to give them a copy of SARS-2 from a tup sekrit US military lab via WIV in turn via HWM in turn via Laos bat caves in turn via racoon dogs in turn via Singapore virologist in turn via Matt King Coal in turn via Moshpit in turn via South Korea in turn via Taiwan in turn via Japan in turn via Netherlands.
That is the lab leak hypothesis to date as far as I know. Stay tuned to this channel for further updates as we head into the 2024 elections. Oh and I’m a paid shill for the Chinese government.
Joshua, fauna is what they sell in wet markets.
RS,
China denies everything even their own existence!
@-rs
” …fauna is what they sell in wet markets.”
As far as I know there is no dispute that the original virus came from fauna. Specifically bats which with their weird immune system live in a state of semi-symbiosis with many viruses.
Some people contend that the mutations that allowed this virus to infect humans, and dogs, and racoon dogs, and pangolins, and cats… could have been engineered by gain of function research in a lab.
OTOH, all that fauna was in close proximity in the Wuhan wet market. With a lot of people. And a cross species jump has happened before, often.
But the origin is of less importance than the societal response and the human susceptibility. Death rates span from ~6000 per million to ~40 per million. Inevitably there is a lot of scepticism about some of the reported death rates, and they are also mediated by the proportion of older people in the population. However the wiki table of highest and lowest national death rates is of some interest.
https://en.wikipedia.org/wiki/COVID-19_pandemic_death_rates_by_country
It is evident that the virus was specifically engineered to kill English speaking people, and Peruvians. (-/s)
Russell –
> Xi’s people dismissing the lab and blaming the fauna?”
In what way are “Xi’s people dismissing the lab and blaming the fauna?”
What are you talking about?
Everett, that’s it in a nutshell! /sarc off
Richard, I’m inclined to think you found that SCIENCEINSIDER piece linked in a conspiracy-theorist website.
Why do I think that? Because if you had read the actual article you’d have know that that selective quote you posted misrepresents the article 180 degrees. Which concludes, on the basis of subsequent evidence, that animal spillover is the most likely explanation.
Still, you do rather neatly prove their point!
BTW Google may help you to learn the difference between environmental samples and live-animal samples, and why a sample from or near the cage the animals were in during December was still worth taking in January. As for helping you to understand how human contamination weeks after the market closed to traders and the public is the sort of Hail Mary pass that characterises a conspiracy theorist running out of road, well I rather suspect God Herself would have trouble with that task.
On Twitter – I’ve been dog-piled because I noted that all of the reports I’ve seen on the latest development explicitly caveated the new findings (although some of the headlines and comments from some scientists certainly didn’t focus on the caveats).
Just another example of how social media just enhances the behavior whereby people think that insults and name-calling and point-scoring enhances the scientific value of their arguments.
The true irony hear is that I’ve seen relatively little acknowledgement (from those advancing a LL view of the events) that they’ve long stressed that there were no samples found of animals with SCoV-2 as a key plank of the LL platform.
Joahua, Science reported last night that:
“Newly unearthed genetic data from samples taken at the Huanan Seafood Wholesale Market in Wuhan, China, after it was closed because of the first cases of COVID-19, have identified animals that may have hosted the pandemic coronavirus.”
The news article reports Maria Van Kerkhove, the infectious disease epidemiologist who oversees the WHO program on emerging diseases and zoonoses was contacted by a researcher who said colleagues had uncovered crucial new data from China that speak to the origin of the pandemic.
” The researcher told Van Kerkhove that a team led by George Gao, former head of China’s Center for Disease Control and Prevention, had sat on potentially important genetic sequences from samples it collected in early 2020 at a Wuhan food market where the first cluster of COVID-19 cases occurred.”
Russell –
How is that:
> Xi’s people dismissing the lab and blaming the fauna?”
They sat on the evidence that would “blame the fauna.”
Richard, why are you lying about Fauci lying?
RickA –
You might be interested in this article where someone with the technical background you lack addresses a number of your questions:
https://www.scientificamerican.com/article/new-evidence-supports-animal-origin-of-covid-virus-through-raccoon-dogs/
On “why no raccoon-dog-sample smoking gun”, there was a paper some time ago (may be one of those mentioned in the thread, data in the Supplementary Material IIRC) which had access to photos taken covertly by animal welfare campaigners.
The suspect cage area contained both farmed and wild-caught raccoon dogs (they look different). Sale of the farmed ones is legal but selling wild ones is illegal. Comparing photos before and after the story broke and investigations began, the wild ones had been “disappeared”. For obvious reasons. Presumably police and officials were being bribed to turn a blind eye to the wild ones, but when the balloon went up the evidence had to be destroyed before unbribed officials showed up.
It makes sense that it came from the wild, both the two strains (different capture sites) and because a farm outbreak would have been like the mink-farm outbreaks, with mass animal sickness and fatalities, and infected farm workers.
If those who worry about pandemic outbreaks could at least agree that the way we farm animals need to improve, that would be great.
Joshua, it’s easy to blame epidemics on other species is easy in Mandarin, as the word for “animal” , 动 物 , dòngwù, combines characters respectively meaning “moving” and “thing ” .
@-rs
“…to blame epidemics on other species is easy in Mandarin, as the word for “animal” , 动 物 , dòngwù, combines characters respectively meaning “moving” and “thing ” .”
Wow, and in English the word animal is from the noun from Latin, based on Latin animalis ‘having breath’ from anima ‘breath’;
Looks like language defines things according to their obvious characteristics.
@-W
“If those who worry about pandemic outbreaks could at least agree that the way we farm animals need to improve, that would be great.”
We could farm a lot fewer animals and still stay healthy.
But excluding that option, the obvious solution is to farm animals in as few large centres as possible with no exposure to other animals, and as few people involved in husbandry as possible. It would also require strict regulation of the health and quality of the meat produced.
Unfortunately this would favour the large agribusiness over the small independent farmer.
Russell –
Please explain what you’re talking about instead of playing games and trying to impress with your intellectual breadth.
As far as I can tell, if anything “Xi’s people” are deflecting blame AWAY from the “fauna” at the market.
Am I right that you disagee with the analyses that shows early infections were overwhelmingly associated with the market, and not the lab?
If so, what is your basis for that disagreement?
who investigation shows 3 lab cases in sept
You already said that many times, Mosh.
And you already have been told to listen to the podcast episode.
If those who worry about pandemic outbreaks could at least agree that the way we farm animals need to improve, that would be great.
im down with that as long as we still get to eat veal , foie gras and live octopus
i draw the line at dog, every part of a pig is good
especially the intstines and brain. ears are too chewy, feet are special
liberty and pork, miss me with the civet
> who investigation shows 3 lab cases in Sept.
There lab cases of what? How were the illnesses diagnosed?
As you prolly now, lab workers going to the hospital for a respiratory infection doesn’t mean much in Wuhan because people who get sick like that go to the hospital, not a primary care doctor.
You seem awfully sure about this. What’s your source?
And if 3 lab workers got ill with covid back in September, that would only make it MORE likely that the lab would have been an early epicenter of a hub of infections.
Did family members of these lab workers get sick? Their neighbors in the areas where they lived? Why only 3 lab workers and not a whole cluster?
You’re not even going with the lab workers went to the market and caused a cluster of infections there line of reasoning.
Your pet theory seems even less supported by evidence than Rick’s.
> im down with that as long as we still get to eat veal , foie gras and live octopus
Foie gras is easy:
https://www.npr.org/sections/thesalt/2016/08/01/487088946/this-spanish-farm-makes-foie-gras-without-force-feeding
All you need is to let them live their lives.
Re the question of whether the Chinese government would be more likely to repress info on a lab- or market-mediated spillover, a good point is that many people might assume that the Chinese government is primarily concerned about perceptions in the west.
But is that true? Might not the Chinese government be equally or more concerned with domestic perceptions? How would that change the magical formulas people use to reverse engineer the motivations behind the actions of the Chinese government?
Wanna read something funny. Read the symptoms of the three lab workers and then think real hard.
As for raising livestock, people who work with chickens, geese, turkeys, etc. have caught bird flu. The case fatality rate rate can be as high as 60%. It is, apparently, too difficult to transmit H2H and too lethal to cross the pandemic threshold. It is doing what viruses do: circulating among hosts, which includes us. It’s adapting. What saves morons is it adapts into something harmless, or into something that kills itself off.
Great time for conservatives to go completely stupid about the CCP so they can make them pay.
China: best place on the face of the earth for nature to do completely unfettered gain-of-function research on avian flu and then leak it from one of its zero-security-level labs.
Joshua,
Here is my simple heuristic – which would cost more?
Suppose you have to choose between rebuilding one level 4 facility or destroy ALL of your wet markets and completely rethink how you feed your cities.
Which one would you prefer?
Call it the auditor heuristic.
Speaking of magical formulas for reverse engineering the motivations of virologists.
> hey mr virologist do you think the cause is
A. your buddies collecting bats for science OR
B. those peasants in the wet market?
Early on, Worobey was one of the virologists who signed a letter saying that a lab leak origin was being written off too quickly in the Proximal Origins paper (and calling for China to be more transparent with data). Anderson was one of the virologists involved with the Origins paper.
Magical reverse engineering formulas for mind-probing virologists (or climate scientists) work 100% of the time.
As long as you can add variables or mix and match them as you like in order to reach your preferred conclusions.
Willard,
The heuristic that the Chinese government applies is the only one of several that might count. Nothing, so far, suggest anything except denial.
So far, the only Chinese heuristic I am seeing is their total denial of their very own existence. 😀
Has Moshpit succeeded in diverting your attention? I, for one, need a lot more direct evidence then drivebys, especially from someone infamous for such behaviors.
I can’t believe anything from the USA government, on this matter, at the moment either. This is the perfect storm for the lab leak conspiracy, as anything can currently go into that mix.
Everett,
Here is what I believe:
https://www.portfoliovisualizer.com/fund-performance?s=y&symbol=GXC&symbols=SPY&startDate=01%2F01%2F2019
GXC vs SPY.
If China wanted to send a virus to gain the economic upper hand, it failed.
But then that might explain why the ZZs invaded, right?
Kidding.
To come up with a big macro story is good for soothsayers. Everybody else should put their money where their mouth is. In other words, unless and until I see real bets, there is little to be gained from any of this. Except perhaps more notes for a next post on beliefs and bets?
I bet I could write it by the end of next week.
Speaking of magical formulas for reverse engineering the motivations of virologists.
> hey mr virologist do you think the cause is
A. your buddies collecting bats for science OR
B. those peasants in the wet market?
Early on, Worobey was one of the virologists who signed a letter saying that a lab leak origin was being written off too quickly in the Proximal Origins paper (and calling for China to be more transparent with data). Anderson was one of the virologists involved with the Origins paper.
Magical reverse engineering formulas for mind-probing virologists (or climate scientists) work 100% of the time.
nobody is reverse engineering the Motivations of virologists.
it would be remiss not to take account of the tribal interests of various groups.
you know like taking note that old white conservative guys fight global warming
Woroby had a reputation to uphold
Michael Worobey, an evolutionary biologist at the University of Arizona who pioneered controversial research into the origins of HIV/AIDS, is the 2009 recipient of Simon Fraser University’s Nora and Ted Sterling prize in support of controversy.
nobody is mind probing except people who think others are mind probing.
the only mind probing going on is your probing joshua.
heres what i note.
1. prior to covid 19 there was debate about the wisdom of any kind of experimentation on viruses. and concerns about animal testing and lab
animal escape.
2. asking experts for their opinion on LL theory post hoc runs a risk
of people takingpositions on an undecidable case that merely reflect
their position on the prior debate.
sadly the only people you should trust MAY be comprimised this is not
reading their minds to say “i know they are comprimised” anymore than
saying white juries might be biased against defendants of color requires
mind reading.
so you you dont have to read my mind. ill say this
i think the case is undecidable on the facts. although there are some possible facts
that could make the case either way
this means that structurally both sides are exploiting uncertainty and missing facts
to bolster their case.
we can always wait for the deathbed confessions
https://dnyuz.com/2023/03/18/a-four-decade-secret-the-untold-story-of-sabotaging-jimmy-carters-re-election/
the only thing the LL conspiracy is missing is william casy and the CIA.
my initial reaction was these LL theory people were just china haters
i had a bunch of the haters followng me on twitter because i worked on facial recognition chips in China and basically defended the CCP and defended geotracking in Korea
basically their whole theory was built around missing data. and the only thing that
explained the missing data was a lab leak.
thats a rather unsatifying explanation and just too easy for avowed china haters.
on the other hand after 4 years of living in china and witnessing a culture of official corruption i cannot simply DISMISS the LL as a conspiracy
misconduct and coverups IS a thing , a way of life.an art form
so i cannot believe in the LL because its built on missing facts . but i wont dismiss it
simply because it has the earmarks of a conspiracy theory.
Just came across this. Isn’t Matt considered a profound thinker about sxke scientific matters?
Perhaps people of Ashkenazi Jewish descent have high average IQs because for centuries their ancestors worked almost exclusively in professions such as money-lending, where exceptional literacy and numeracy were rewarded with greater fecundity.
I wonder if his thinking on evolution reflects his thinking on the origins of SCOV-2?
Just to be very clear here, there two LL thingies going on here.
The lab leak hypothesis and lab leak conspiracy ideation.
You know you are on the conspiracy ideation train if you believe Fauci had anything to do with the SARS-2 out brake, for example.
The scientific evidence to date suggests a natural origins hypothesis versus a lab leak hypothesis.
China at the start didn’t handle it well but having a US President making accusations of it coming from a lab as almost the first things said about it – and Australia’s Prime Minister at the time, a fan of Trump, repeating them and demanding international investigations – was not a good start for any cooperation in doing so.
In Trump’s and Morrison’s case – neither standing out for the quality of their early domestic responses – there looked to be popular political advantage to be had in accusing China and stoking “out of a lab” conjectures.
A couple of years on the accusing and stoking of distrust of China continue and I don’t think getting to the truth is the point of it.
Steven –
> nobody is reverse engineering the Motivations of virologists.
Well, that’s clearly not true more generally, but I think that’s reasonable interpretation of your assumption that a virologist asked about SCoV-2 origins would answer in a way so as to protect his/her colleagues and not in a way so as to give the best answer.
> it would be remiss not to take account of the tribal interests of various groups.
First, there could be different tribal interests in play. There’s a tribe of scientists who are motivated to conduct science optimally. There’s a tribe of virologists who think that providing the best answer is the best way to advance the cause of the tribe of virologists.
It’s your assumption that a virologist concerned about his/her “tribe” would dictate an answer motivating against acknowledging a lab leak if one occurred. If a virologist thought a lab leak would occur, it would behoove him/her to be honest about his/her opinion.
So you’re mind-probing into a virologist’s head to determine what his/her motivation is.
> Woroby had a reputation to uphold
Woroby presumably has many considerations, including protecting his reputation. Originally he said said more investigation should be done and that the Proximal Origins paper was too dismissive of a Lab Leak. Then he said that the evidence favors a “natural” spillover event. So where do you get that his concern about his reputation leads to him avoiding a Lab Leak explanation>
> nobody is mind probing
Well, that’s CLEARLY ridiculous.
As to whether you’re mind-probing….
> except people who think others are mind probing.
I’m not mind-probing by describing your mind-probing. I haven’t said boo about your motivations for making a asinine argument.
> sadly the only people you should trust MAY be comprimised this is not
reading their minds to say “i know they are comprimised”
No, it isn’t. It’s reading their mind to suggest that their answer when asked about lab leak will reflect a particular bias in a particular way – which is what you did. Of course asking a virologist about a lab leak may produce an answer biased towards “blaming the fauna.” Or it may not.
> i think the case is undecidable on the facts.
I think that’s a facile binary. It doesn’t have to be “decidable by the facts.’ The facts can inform the probabilities.
> this means that structurally both sides are exploiting uncertainty and missing facts
to bolster their case.
To the extent that there are sides biased in one direction exclusively of the other, probably true. Worobey first staked his reputation on saying that the possibility of a lab leak was being closed off to soon. Now he has written a paper saying that a market-mediated spillover is much more probable. So where is his exploiting the uncertainty and missing facts, oh swami?
we can always wait for the deathbed confessions
> my initial reaction was these LL theory people were just china haters
Why is your initial reaction important? When did this become about you?
> i cannot simply DISMISS the LL as a conspiracy
The fact that not everyone creates a conspiracy theory to support a belief that there was a lab leak doesn’t mean that many LL believers aren’t grounding that belief in a conspiracy theory.
> misconduct and coverups IS a thing , a way of life.an art form
No kidding.
> so i cannot believe in the LL because its built on missing facts . but i wont dismiss it
simply because it has the earmarks of a conspiracy theory
No one here is dismissing the possibility of a lab theory because some people are basing their view of the origin of SCoV-2 in a conspiracy theory.
I keep explaining that to you. It’s not a hard concept.
Best Moshpit one liners so far …
In 2nd place is …
“on the other hand after 4 years of living in china and witnessing a culture of official corruption i cannot simply DISMISS the LL as a conspiracy”
So all about Moshpit and their sleuthing into government corruption in China but we all know that it happens all over the globe because there is most certainly corruption wherever one looks by ALL governments. D’oh! Non Sequiter.
In 1st place is …
“i take it youve never seen chinese construction”
Actually the world has seen Chinese construction …
China State Construction Engineering
https://en.wikipedia.org/wiki/China_State_Construction_Engineering
“The China State Construction Engineering Corporation (CSCEC) (Chinese: 中国建筑集团有限公司) is the largest construction company in the world by revenue and the 8th largest general contractor in terms of overseas sales, as of 2020.[2][3]”
[Playing the ref. -W]
The 2014 Ebola outbreak may have been borne out of an accidental lab leak at a US Government-funded facility, according to a bombshell analysis.
Virologist Dr Jonathan Latham — a former researcher at the University of Wisconsin — and journalist Sam Husseini say there are a number of inconsistencies in the official timeline of the West African epidemic.
They claim the virus likely emerged during ‘routine research activities’ from a laboratory in Kenema, Sierra Leone, which at the time was receiving funding from the US government for its work on Lassa fever.
The lab specialized in hemorrhagic viruses similar to Ebola — though it’s unclear whether it actually handled the epidemic-causing pathogen.
Most experts still believe Ebola emerged naturally during a spillover event from animals in Guinea, around 175miles from the lab.
Bats known to harbor Ebola were identified in a village where the first official patient was diagnosed — but researchers never found the original animal host.
An independent expert responding to the findings told DailyMail.com the theory was ‘certainly possible’, but raised several questions about the credibility of the authors
https://www.dailymail.co.uk/health/article-11383611/Ebola-leaked-biofacility-causing-2014-West-Africa-outbreak-scientists-claim.html
In 1st place is …
“i take it youve never seen chinese construction”
Actually the world has seen Chinese construction …
actually not.
try
there are two sides to the costruction.
1. they do things incredibly fast
2. their finish work sucks
you know what finish work is? right? you see that apartment build that
goes up in 1 day? none of the interior hallways will ever have its finish
work done. the hallway will be bare concrete, no underlayment, no flooring
no carpet, no final coat of paint. no door trim. all the detail work. skipped
the other thing is if you are not there to watch the work, they will short cut.
absolutely. even in electronics if you specify a 1% resistor they will
change it to a 10% resistor to save 1 rmb. apple took a while to learn this.
sorry i’ve been building stuff there since 1995.
some hints
http://www.quality-wars.com/2009/09/23/how-to-tell-if-a-factory-is-cheating-you/
what does this mean?
when DOE and FBI report that the lab in wuhan had a problem with
ventilation in sept 2019
I AM NOT SHOCKED!!! it comports with experience that i have.
like if trump changed rail safety standards and then there was a crash, would that SHOCK you?
well if you had experience in the rail business you might say “Hey, thats not hard to believe”
now if you told me the Swiss lab had a ventilation system problem or the germans had a problem, id say “ARE you sure?
next question when it came to selling PPE which product woould the us government accept
chinese N95
korean N94
and why? what did they know?
which product could you carry out of korea?
why?
OK. Enough food fight, and no more playing the ref.
So Matt has seen where Marx got it wrong, Joshua?
An international conspiracy of smart Jewish bankers and financiers.
No wonder they successfully oppressed the working class this last century and a half!
And of course they sabotaged the USSR. Probably even bribed Stalin to send millions to the gulags, and Mao to condemn millions to death by starvation.
Dave,
You might be surprised what some people might say, particularly if you back them into a corner of their own doing.
The speed with which they built the Empire State Building, 1931

Of course now with prefab, prebuilt and prestressed parts, buildings can now go up extremely fast, considering that 92 years have passed since the ESB was constructed. I am now speaking as a structural engineer not just a civil engineer. The structural strength of any building being of the upmost importance. Knowing that a lot of China’s buildings are unfinished comes as no surprise as someone who has known this from relevant subject matter experts for over 30 years now.
raccoon dog crossover origin at tvhe Wuhan live market is getting some discussion from dna analysis: https://thehill.com/homenews/3905130-new-study-cites-wuhan-raccoon-dogs-as-possible-origin-of-covid-19/
I believe that the folks who want to believe the wuhan lab escape source story are unlikely to process this new information, but it’s just scientific evidence.
Darn raccoon dogs, anyway.
Mike
“This search for the wild ancestors of SARS-CoV-2 is driven today by the “spillover” theory. This theory, as formulated by Power and Mitchell (2004), states that there must be an “animal intermediate species” also often referred to as “reservoir” bearing the same virus as the one causing the epidemic. This spillover theory is the reference driving strategies for preventing and controlling emerging infectious diseases at the early stage. It is at the origin of the search for intermediate species and screening projects such as the Global Virome or PREDICT (Carroll et al., 2018; Jonas and Seifman, 2019) which objectives are to identify potential zoonotic viruses circulating in the wild. In the COVID-19 context, this intermediate species is supposed to make the link between bats, the putative original virus reservoir (Burki, 2020; Boni et al., 2020) and humans, the final recipient host. However, none of the predictions from the spillover model have been confirmed. …” – Roger Frutos, “There is no “origin” to SARS-CoV-2”
Interesting article:
https://www.newsweek.com/covid-lab-leak-china-virus-nuclear-war-1787390
@-RA
So you consider an entrepreneur who is also pushing his companies’ breast cancer drug is an acceptable expert on gain of function in virology research ?
With a commercial interest in Taiwan is it any surprise he views the Chinese government as an existential threat by developing a highly virulent bioweapon.
RickA,
We already covered that.
Here: https://andthentheresphysics.wordpress.com/2023/03/13/the-origins-debate/#comment-216692
I asked for odds many times already, and suggest your next comment give me some.
RickA –
> Knowing FCSs were not found in nature in these SARS-related viruses…
I’m guessing you like to identify as a “skeptic.”
Did you look at that “interesting” article with a skeptical eye?
Isn’t this a classic example of ad hominem?
izen, I don’t mean to pick on you. Seriously. I’m just using you as a cheap ‘foil’ for making a larger point about where argumentation here in this blog has generally devolved. I’d have said the same thing regardless of who the individual is. So it’s not about you. Just about this particular blog discussion.
[Snip. Playing the ref. -W]
Jon –
> Isn’t this a classic example of ad hominem
The track record of people who have a history of making confident but likely erroneous arguments in other areas where they lack experience and expert knowledge can’t be considered dispositive with regard to their arguments about virology – where they likewise lack experience and knowledge – but it is relevant for assessing the probabilities as to whether their arguments about virology are valid.
At some level, track record has relevance although it can’t be considered sufficient for evaluating someone’s analysis.
If you look at that article that RickA linked, and then do just a small amount of follow on investigation, there is much material that suggests the author of that article was wrong at the most basic of levels.
Here we go.
More on the non-conspiracy theory, conspiracy theory about 15 Minute Cities and Oxford.
https://thewaroncars.org/2023/03/21/conspiracy/
Steven, get out your clutching pearls. Stat!
Actually, it’s pretty good discussion of the etiology of rightwing anti-big government conspiracy theories.
My, what a busy comment thread! Regarding China’s motivation, keep remembering they’ve been trying to maintain the virus didn’t originate there at all, so muddying the waters on lab OR market origin would both be something the Party might see as in their interest (and I speculate, like the rest of us here).
Don’t forget, they’d been making a show of disinfecting pallets of imported frozen foods, long after everyone else concluded the origin was -somewhere- in Wuhan.
Here’s another bit for the market origin using the briefly-released swab data – though they are staying at preprint and aren’t releasing that data that was up and then gone again, until a paper about it going through peer review in China gets published (according to the coverage).
ArsTechnica : “Here’s the full analysis of newly uncovered genetic data on COVID’s origins: The genetic data paints a picture of spillover in one zone of the market.”
https://arstechnica.com/science/2023/03/heres-the-full-analysis-of-newly-uncovered-genetic-data-on-covids-origins/
And the underlying preprint: “Genetic evidence of susceptible wildlife in SARS-CoV-2 positive samples at the Huanan Wholesale Seafood Market, Wuhan: Analysis and interpretation of data released by the Chinese Center for Disease Control”
https://zenodo.org/record/7754299#.ZBoRMezMI-S
Apparently it’s technically not a preprint, but a report.
some wisdom
Steven, get out your clutching pearls. Stat!
Actually, it’s pretty good discussion of the etiology of rightwing anti-big government conspiracy theories.
i heard a crazy story the other day about the US government doing experiments on african americans in tuskeegee.
what a load of right wing anti big government bunk!!
let me put it this way. we all look at this case and think
“well theres evidence and missing evidence on both sides, circumstantial
evidence all around.
so WHY are these people so certain its the lab?
must be right wing conspiracy nuts—- like that JFK thing, like 9-11 truthers
and i think why are those “spillover people so certain given the sketchiness of the data? must be racists.
im not a fan of big government, but if i have to pick one it would be the CCP
they get shit done
https://bigthink.com/the-present/conspiracy-theories-2653392476/
As it happens, in the pod they talk about how many conspiracy theories are bard on real phenomena, as indeed is the 15 minute city conspiracy theory. Lots of good connections to the climate wars conspiracy theories – like the ONE WORLD GOVERNMENT!!!!
My favorite actual conspiracy is MKUltra.
Conspiracies happen. And even implausible conspiracies happen. And people push implausible conspiracy theories. There’s no mutual exclusivity there.
It’s high time for you to get out of your binary thinking trap. I think you’ve been stuck there for far too many years.
And besides, be proud of your conspiracy theories.
If I ever wanted to be taken srsly about my conspicracy, I would make sure to check out thy Wiki first:
https://en.wikipedia.org/wiki/Wuhan_Institute_of_Virology
French engineering usually gets things right. But then the conspiracy might explain why French folks are in the street as we speak.
Oh, and the Guru podcast kinda specializes in the Weinstein bros, e.g.:
https://decoding-the-gurus.captivate.fm/episode/eric-and-bret-weinstein-a-dark-horse-gallops-through-the-portal
The truth is out there.
@-JK
“Isn’t this a classic example of ad hominem?”
No.
calling into question the expertise of a person and their political bias when they are cited as a source of neutral expertise for advancing an opinion is not an ad hominem.
It is questioning not only the expertise and neutrality of the source cited, but also the credibility of the person who cited it.
Joshua said: “Apparently it’s technically not a preprint, but a report.”
So it is! Thanks for catching that mistake. It seems they’re doing an “OK, we’re fed up” way of not -officially- publishing prior to the Chinese paper. While putting it in an open repository. Remarkable to need to go through three full pages of Introductory Remarks before even getting to the title, and then to this on the title page:
“Some of the information contained in this report was initially communicated to the World Health Organization (WHO) on 11 March 2023 (PST), and presented to the WHO’s Scientific Advisory Group on the Origin of Novel Pathogens (SAGO) on 14 March 2023.This report is not intended for publication in a journal.”
Speaking of conspiracy theories that Steven has a hard time acknowledging our conspiracy theories:
As for he recent good fight.
Here’s someone who’s a respected virologist who has been involved in the discussions for quite a while (leans LL).
If you dig beneath the conspiracy theory, you’ll see that Quay, Washburne, Battachayya, etc. were wrong.
The two tweets look the same.
Sorry:
That was a pretty funny mixup. Near as I can tell, neither Washburne nor Quay remotely resemble my discription. And both serve as good examples of why evaluating expertise is not necessarily am ad hom.
Good news everyone:
A journalist is not bashed by a scientist for a change.
For every invalid appeal to authority there is a valid ad hominem. For every valid appeal to authority too. Anyone who wants to become an authority needs to prepare to be questioned. One way is to get through the education system. Nowadays this extends to social media.
Let me ask readers (if there are any left) – what is credibility worth? In my world, the fantastic world of ninjas, it is worth everything. What I write under my name is my honour.
Every respectable schooling system has an honour code. So I suspect that credibility extends beyond my fantastic world.
Credibility warrants loans. Without it the credit system falls in a week. But in contrast with institutions, personal credit comes in finite amount.
So yeah, the fact that Matt King Coal bankrupted the first bank in England in 150 years matters quite a bit to me. He might still be right {1}. But he has no credibility left, and anyone who lends him any devalue theirs.
In my opinion.
{1} Assuming one can be right by Just Asking Questions.
wrt what’s important in life, this kind of ffs might have made a difference at the beginning of Covid, when the spread could have been stopped. The people who could have done that were hobbled, and the result was predictable. Blaming Fauci, not so much (I’m still furious about that).
https://i.guim.co.uk/img/media/7e0dca92c694319fc58cc96c80db63ab1ae61319/0_0_2835_2043/master/2835.jpg?width=940&quality=85&auto=format&fit=max&s=79265c3b89b311d4b735de87d8482585
Oh well, the second image didn’t come through. It reads: “FFS Don’t Keep Calm and Carry On” …
what kind of work were these guys Proposing????
https://www.documentcloud.org/documents/21066966-defuse-proposal
TLDR: we found some nasty bats in caves, carrying COV. we w
ant to experiment
on them.
by the way humans within 6km of the caves are already infected 3% seroprevelance.
darpa is not dumb they denied the grant request.
wrt what’s important in life, this kind of ffs might have made a difference at the beginning of Covid, when the spread could have been stopped. The people who could have done that were hobbled, and the result was predictable. Blaming Fauci, not so much (I’m still furious about that).
so i was in china until jan 23 2020. right before wuhan lockdown.
i went into work, face recognition is my key to the building.
then sign in at front desk.
im handed a mask. im like oh shit this is no joke.
i move my flight from 24th to 23rd.
after work i goto 7-11. the sweet auntie behind the counter hands me a N95
my mask is no good.
the hotel staff is disinfecting everything. there are boxes of toothpicks in elevator for pushing buttons. no joke
i leave on the 23rd. hotel hands me a N95. i head to korea.
in korea the head of the CDC announces a msk shortage and within
1 day they arrange mask rationing
” our doctors and nurses need masks. we ask the public to please abide by the
rationing plan. your birthday drives your allocation.
CDC head coughs into his hand (not elbow) on TV.
removed from office. replaced with a fantastic lady
meanwhile in the USA our public health officials say “masks dont work, save them for doctors and nurses”
the day united arab emrites opened to tourism, i flew there.
i did two tours of quarantine in korea.
bottom line: our public health officials, yes DR. F, were pitiful in comparison
ask me why i loved watching this amazing lady twice a day
Alright, Mosh.
I think that’s enough.
The full blame belongs to Small Hands and not Fauci. Small Hands not Fauci, you GOP synchophant.
Please, let us chill.
https://www.nature.com/articles/d41586-023-00827-2
“The new study does not confirm whether the animals themselves were infected with the virus. But establishing that the animals were present at the market supports the hypothesis that the pandemic had an animal origin, say some researchers.”
So the specimens were collected in early 2020, months after the pandemic started. AND they don’t show any infected raccoon dogs – just raccoon dog dna. Isn’t that pretty weak?
Here is an interesting thread on a possible source of COVID from a mahjong room near market:
What I would like to know is if any lab workers played mahong at that location and/or visited that wet market. Maybe the Biden declassification, which will identify the lab workers who got sick in 2019 will help shed light on this. If there is a link between sick lab workers from 2019 and a superspreader event at the market that would be damning evidence of a lab leak – would it not?
Richard,
As I understand it they do have raccoon dog DNA in the same location as the find SARS-CoV2. Also, noone is claiming that there definitive evidence that the pandemic sarted through a zoonotic spillover in the market, but there is much more evidence linking the start of the pandemic to the market than there is linking it to the lab. In fact, I’m not aware of any actual evidence linking SARS-CoV2 to the lab.
Yes – they have mixed dna. Raccoon dog DNA, human DNA and SARS-CoV2 DNA. And the swabs were collected from the market in Jan., Feb. or March 2020. But given that the pandemic was raging in wuhan in Jan, Feb. and March 2020, you could swab any part of Wuhan and find human DNA, animal DNA (from pets or dinner) and COVID dna during this time frame.
So, this points to evidence of the pandemic at a location, and maybe the first location humans who got sick worked (at or near). But not how they got sick in the first place. Could have been from an animal or it could have been from a sick person who gave it to them at that location.
So both sources are still in play and more evidence is needed to pin down whether it was a spillover or a lab leak.
Now I am wondering about the early Nov. and Dec. people from outside China who got sick while in China. I wonder if they can be traced back to the market or playing Mahjong near the market? I wonder if they can be traced back to any lab workers. I wonder what their contact tracing shows that could help pinpoint the start of the pandemic. Does anybody know?
See https://health.ucsd.edu/news/releases/Pages/2021-03-18-novel-coronavirus-circulated-undetected-months-before-first-covid-19-cases-in-wuhan-china.aspx
RickA –
I can’t help but notice the pattern whereby you keep raising questions questions but pretty much ignore any of the answers provided. Regardless, you say:
> If there is a link between sick lab workers from 2019 and a superspreader event at the market that would be damning evidence of a lab leak – would it not?
It’s interesting that you note that there was no direct evidence of infected araccoon dogs but seem to not note that there was no evidence of infected humans. So 2 months after a highly infectious virus started spreading exponentially, there was evidence of the virus and evidence of the raccoon dogs but none of humans that were infected. This despite what you think were months of exponential spread among lab workers who you seem to think came to the market. And you think there was a bunch of infected lab workers walking around and yet there’s no evidence of those lab workers spreading the virus outside of the market. As I’m sure you know the evidence of the spread at that point was still highly centered around the market.
It seems that you’re interest in what has and hasn’t been found is highly selective.
Richard,
As Joshua highlights, there is still no evidence – as far as I’m aware – between SARS-CoV2 and the lab, while there does appear to be direct evidence linking the outbreak to the market. So, you “just” seem to be “asking questions”.
Joshua:
There is plenty of evidence of infected humans. From the link I gave in the post above yours, the first human infected evidence dates back to Nov. 17, 2019. Well before any people clustered near the market. In fact there is only evidence of sick humans and zero evidence of infected animals (so far). I would argue that is evidence of the lab leak – since we know they were fooling around with making bat coronavirus transmissible among humans and humans were the source of the infection (so far). With only infected humans dating back to mid Nov. 2019 and ZERO animals infected dating back to Nov. 2019 – what is the most reasonable conclusion?
But reasonable minds can differ.
From the paper I cited above:
“The first cluster of cases — and the earliest sequenced SARS-CoV-2 genomes — were associated with the Huanan Seafood Wholesale Market, but study authors say the market cluster is unlikely to have marked the beginning of the pandemic because the earliest documented COVID-19 cases had no connection to the market.”
RickA –
> There is plenty of evidence of infected humans.
Why did you change the topic? You had been discussing the genomic evidence discussed in the recent reports.
Despite my better judgment I’ll follow your curious topic change
> Well before any people clustered near the market
There have been two analyses of the data on the early infections in humans and found those infections overwhelmingly associated with the market. To the point of arguing for a very high statistical probability that the origins outbreak was associated with the market.
Surely you must know this.
Since you’ve got so many questions about the origins of the pandemic, surely you must be aware of those analyses.
Now some have argued with that science (arguing that there was ascertainment bias) but it seems odd to just ignore those analyses. It would be amusing to see you weigh in to provide your assessment of whether there was ascertainment bias (make sure you read the appendices where they discussed the possibility of ascertainment bias before you do so) but regardless, I’m quite sure that you have zero evidence associating an early outbreak with the lab – because no such evidence exists. Why aren’t you asking questions about that?
Here’s a question for you: Why do you favor the lab as the origin of the outbreak even though there’s no evidence of widespread infections centered on links to the lab? At best there is uncertain evidence about a few lab workers who had some kind of an influenza-like illness and who went to a hospital for care. But it’s not clear that they had covid and like I said, if they’d had covid there’s would likely have been an outbreak of many infections associated with those workers or with the lab.
With all your questions you seem as uncurious about that as you are determined to ignore answers to your questions.
And please note that the co-authors of the paper you linked subsequently co-authored an extensive follow up analysis – one of the two analyses I point you to way up thread that provide evidence that the geo-spatial evidence supports a market-mediated spillover:
https://www.science.org/doi/10.1126/science.abp8337
RickA,
I still note that you are still Just Asking Questions without having given me odds.
Is it because you have less confidence in your pet theory out of a sudden?
Also, I note that you are now relying on DRASTIC:
https://drasticscience.com/
Do you happen to know why Rosanna Segreto left that group?
Many thanks!
Oh, and just to save us some time, here is what I am asking you to find back:
https://twitter.com/Rossana38510044/status/1507316648956645378
I am sure you can find a copy of that tweet somewhere.
Please report.
Willard:
I don’t get this odds thing you are so insistent on. I told you how much I was willing to bet. I am not much of a gambler – so I don’t do the odds thing (whatever that is). I am also not interested in reading your links about drastic and rossana or your homework assignments. I am just sharing my opinions about the origins of COVID and links which I think are relevant.
RickA,
I already explained how betting odds work and thus will presume that you are just playing dumb.
Rossana’s tweet reveals that she wasn’t too happy that DRASTIC turned into a conspiracy megaphone.
So I duly submit that you have peddled enough for one thread.
Thank you for your understanding.
“At times it felt almost meta. Lying about lying about lying.”
My understanding was that swabs were taken very early in January 2020 say between the 1st and 3rd if I’m not mistaken. Just after they closed the market.
Camouflage ->
[More peddling. -W]
It seems likely to me that Covid was zoonotic spillover from the raccoon dogs at the market, but I think it is still possible, but less likely that the pandemic started from a lab leak. I suspect that is about as certain as we will ever know about the origins of Covid. I have lost track of the reason why it matters which source initiated the pandemic. What is the significance of that?
I think it is a fact that humans will be subject to more cross-species infections because we have expanded our civilized territory over so much of the planet that the wild animals that are left on the planet exist in close proximity to lots of humans now. This has not always been the case. Think it makes sense for humans to think about the public health implications of human expansion into close proximity with populations of wild animals that provide the basis for zoonotic infections. What can be done that would help with the public health implications?
I think it is a fact that humans will always be subject to leaks of dangerous chemicals and substances when humans work with dangerous chemicals and substances. It makes sense for humans to think about the public health implications of work with dangerous chemicals and substances in labs, or factories, or injection wells, etc. What can be done that would help with the public health implications of this work?
The question of the covid outbreak leaves us looking at two potential sources. Which one should we look at so that we could be safer in the future? Both of them. This does not look like an either/or situation to me. This looks like a both/and situation. Am I missing something important about the discussion?
> Am I missing something important about the discussion?
Yes, Mike. You missed that I asked Rick to stop peddling. Questioning him can only lead to more peddling.
my bad
Just me, but it seems more likely that a human being brought the virus to the market and it was able to infect some of the live animals. This human being was probably active in catching and trading wild animals in SE Asia. It is also possible this person infected some of his animals, and he brought them to the market to sell them. Either way, the source, the origin of SARS-CoV-2, is most likely a human being, but probably not from China. Just as the Delta variant originated in a human being, and just as Omicron originated in a human being.
“In doing so, the research team found viruses with Omicron-specific mutations in 25 people from six different countries who contracted COVID-19 in August and September 2021—two months before the variant was first detected in South Africa.
They then sequenced the viral genome of 670 samples. In doing so, the team discovered several viruses that showed varying degrees of similarity to Omicron, but they were not identical. “Our data show that Omicron had different ancestors that interacted with each other and circulated in Africa, sometimes concurrently, for months,” explained Drexler. “This suggests that the BA.1 Omicron variant evolved gradually, during which time the virus increasingly adapted to existing human immunity. …”
JCH,
Which came 1st the chicken or the egg? I mean, there is proportedly a source wence came SARS-2 or something SARS-2 like. In other words, a precursor genome. Like I actually know what I am talking about? Which, you know, I don’t.
Time for the subject matter experts to step in, yes?
I’m not a good enough internet sleuth to concoct my own conspiracy ideation, and just like RickA, I need others to do my conspiracy ideation for me, if i were ever want to go down that path, which I won’t. It’s pretzel logic all the way down if you do decide to chase ghosts though.
JCH –
> Either way, the source, the origin of SARS-CoV-2, is most likely a human being,
Why do you think so? From what I’ve gathered (all of my gathering as someone with less than any domain expertise must be taken with a grain of salt) the fairly rapid evolution of the virus after the initial outbreak may indicate that it wasn’t evolving for very long in interaction with the human immune system prior to the outbreak.
> My understanding was that swabs were taken very early in January 2020 say between the 1st and 3rd if I’m not mistaken. Just after they closed the market.
Apparently they sampled on January first and then came back to that corner of the market to sample again on January 12th. Leaving the question unanswered why they came back to sample that particular location.
Discussion with Holmes and Rasmussen, where I expect they addressed many of the questions that are raised by people who are just asking questions.
Not that anyone here is just asking questions, of course.
https://t.co/eY74Gaot4J
Here is a paper which concludes the spillover is more likely than the lab leak.
https://journals.asm.org/doi/pdf/10.1128/msphere.00119-23
RickA –
Please note:
https://andthentheresphysics.wordpress.com/2023/03/13/the-origins-debate/#comment-216607
Joshua:
Oops – sorry for the repost of the link to the same paper.
I stopped at:
> The Merriam-Webster online dictionary defines a hypothesis
But then I skipped to the end, and noticed:
> the available evidence favours the latter
What is the latter?
This was concise:
https://www.spiegel.de/international/world/the-search-for-the-origins-of-sars-cov-2-the-results-on-my-screen-were-raccoon-dog-raccoon-dog-raccoon-dog-a-b13d1899-6544-4128-b748-5eaa67ee36cc
Willard –
> I stopped at:
>> The Merriam-Webster online dictionary defines a hypothesis
Is this a critique of the paper? If so, how?
> What is the latter?
Hypothesis 3 and 4.
J,
Back in my days, we were thought not to start our essays by quoting dictionary definitions. In this case, it looks patronizing and silly. More so that they continue their forensic by using technical jargon that prolly remains undefined.
Also, it reminds too much of Lucia’s, the parsomatics Mecca where semantic arguments reigned.
If they wanted to do a plain language summary, they could have asked an editor for help. Or a journalist. Or just skipped the paper altogether and do a YT video.
What are hypotheses 3 and 4?
Willard –
Sure – I find quoting dictionaries (and maybe particularly so online dictionaries) weak rhetorically, but looked past that as more or less irrelevant froth to the meat of the discussion. And I do appreciate the recognition of defining terms.
As I understood it…
3, is that it’s a bat virus
4, is that the clustering is suggestive of origin.
OK. I read it. So there are two major hypotheses, but the authors discuss four. That make six hypotheses, right?
Also, the authors present the scientific method, which is that you formulate some hypothesis, you then make a prediction, which you then test. That does not sound like what they did. In fact they do not present how they reached their conclusion.
At least they lay down the evidence and explain it clearly, so there is that.
If I was rating an essay, I would give it a C or a D. I see a solid evidence basis, but no inference engine and shaky conceptual support.
Willard
I found the overall organizing structure a bit incomprehensible. Nonetheless, there was much I found useful. For example: I hadn’t realized previously that serial passaging would likely result in the loss of the furin cleavage site.
And along similar lines, I find an aspect of their structure useful, whereby they argue that hypothesis 3 and 4 are “favored” by virtue of 1 and 2 being scientifically unlikely (a position for which they present clear scientific arguments).
In the context is this debate, where we’re looking to evaluate the probabilities among different views where dispositive evidence (such as finding a true ancestral animal) will not likely ever be be found, I think that’s an interesting approach. Direct evidence *for* 3 and 4 will almost necessarily be limited, so the direct evidence *against* 1 and 2 stands out.
Joshua:
You cited it but Willard and I didn’t read it. I cite it (having found it on Google Scholar) and Willard automatically doesn’t like it (probably because I cited it)- even though it agrees with his bias. Interesting!
Joshua:
I criticize a paper that supports the opposite side of Rick’s opinion. Instead of seeing this as a sign of openness, he makes it all about him.
Hmmm. Big hmmm.
Here’s an alternative interpretation. Rick rediscovers a paper you already cited. This means it is a paper that is making the rounds. So I click on it again, and again see this lousy first sentence. I react to it, and then give it a second look because you question me.
Contrarians never lose.
The main thing that I think is relevant about the paper is the arguments and evidence presented.
I learned from it. That serial passaging would likely result in the loss of the FCS (if true) would seem (to me to be) very important re the widespread belief that SCoV-2 was engineered and then spread through a lab leak, and of course all the associated discussion about the threat of GOF research.
I should say “…engineered in a lab through serial passaging (as opposed to de novo – although as discussed under “evidence C” under “hypothesis 2,” the loss of the FCS would likely affect the possibility of de novo engineering as well!)
Again, although there’s reason to criticize the organization at the top level perhaps, with the caveats as someone who knows less than nothing on the topic, I really appreciate the logic of how the arguments fit together.
So a virus can spill over from an unknown animal to a human being, but not from a host we know had been infected by SARS-CoV-2 at the market, human beings, to animals?
Ask a mink.
Wu, 2023:
https://www.sciencedirect.com/science/article/pii/S0013935123002736
Highlights
•
The pattern of BsmBI/BsaI restriction sites is highly diverse in coronaviruses.
•
Endonuclease fingerprint does not indicate a synthetic origin of SARS-CoV-2.
•
Creating a SARS-CoV-2 virus in the laboratory is extremely challenging in practice.
Second, the hypothesis based on serial passaging is seriously problematic because it assumes that the virus would directly evolve into being more infectious. A more common result is that the virus will be more adapted to the cell line or animals used for passaging and becomes less virulent to the original host (Badgett et al., 2002; Ebert, 1998). Even if we assume that there is an ‘imaginary’ live RaTG13 virus in the WIV laboratory and the evolution goes as we expect, the time for serial passaging to obtain SARS-CoV-2 from RaTG13 is also tremendous. The measured spontaneous mutation rate of SARS-CoV-2 during experimental evolution is 1.3×10−6 per base per infection cycle, which is equivalent to 0.039 mutations per infection cycle (Amicone et al., 2022). One infection cycle in cell culture is typically 1–3 days depending on the inoculated viral MOI (multiplicity of infection) (Amicone et al., 2022; Hasler et al., 2021; Wurtz et al., 2021). So, to generate directed mutations on those 1182 nucleotides in RaTG13, we would need at least 121,230 days (332 years, equals to 1182/0.039*4) by serial cell passaging. …”
So0me facts
One chilly morning in February 2017, a tall Chinese scientist in his 50s named Yuan Zhiming showed Bernard Cazeneuve, then the French prime minister, around Wuhan’s new high-security pathogen lab. Built with French engineering, it was China’s first P4 lab, one of several dozen in the world with that highest security designation.
–
A new pandemic origin report is stirring controversy. Here are key takeaways
–
Last week, journalists rushed to report on previously undisclosed genetic evidence
–
Florence Débarre, an evolutionary biologist at CNRS, the French national research agency, who has become prominent on social media for her analyses of COVID-19 data and also sparring with lab-leak proponents, says she stumbled onto the sequences and shared them with colleagues.
–
49 of those samples infected with SARS-CoV-2 RNA also contained mitochondrial DNA (mtDNA) that clearly identified five mammals: the common raccoon dog, Malayan porcupine, Amur hedgehog, masked palm civet, and hoary bamboo rat. The group produced a “heat map” that shows the density of SARS-CoV-2 was “hottest” in market areas near stalls that sold the mammals. *****
–
But critics, many of whom suspect SARS-CoV-2 may have escaped from the Wuhan Institute of Virology (WIV), say the new sequences offer no great insight beyond the confirmation that the seafood market also sold mammals.
JCH –
> So a virus can…but not from a host we know had been infected by SARS-CoV-2 at the market, human beings, to animals?
Who has made the argument that a (generic) virus “can’t” spill over from a human being to an animal?
For those genuinely interested, Alina Chan and Matt Ridley wrote an excellent book titled Viral. I loaned out my copy but from memory the most important evidence has barely been touched by this string. Steve Mosher brought up the DARPA proposal by Eco Health to have the WIV insert a furin cleavage site into SARS to make it deadly to humans. DARPA said no thanks in 2018, but as Mosher points out, left over grant money is typically used to start research for the next grant proposal. Sometimes they may even start lab work, just to be sure what they are proposing is possible. It would be reasonable to think what might have been of interest to DARPA would also be of interest to the CCP. DARPA was maybe a yes if the lab was Fort Detrick, MD.
No other SARS virus in the wild has a FCS. pangolins, civet cats and racoon dogs do not have any coronaviruses of any type in the wild. This according to Eco Health’s own field studies looking for them since 2003 SARS. The is one reason why Ralph Baric and others had changed their minds about SARS1 origin as being a civet cat. The main reason for the Menachery (2016) chimera SARS gain of function research funded by Fauci in the WIV was so Baric could find evidence of possible direct bat to human vulnerability to SARS. (I downloaded the 2016 Baric podcast from This Week in Virology before they scrubbed it from Menachery’s web page in 2020. ) The only thing is that Baric’s partner, Zhengli Shi, already knew the answer to this question for 4 years by 2016.
We know this thanks to a Twitter account known as The Seeker and a translated Chinese Master’s thesis that there was a 2012 event in a Hunan copper mine where 6 workers became infected with a SARS-like illness after clearing bat guano. According to the thesis medical samples were sent to Zhengli Shi and the older 3 of the 6 men died in the hospital. Shi set up expeditions to this copper mine as her top priority for the next 5 years, collecting many thousands of samples until she found what she was looking for. From all the expeditions research she only published one paper, revealing just one of the eight SARS-like viruses found and made no mention of the location of the mine or of the deadly SARS-like infection associated with it. That one published virus Shi identified as Bat-cov4991. Months after Shi’s 2020 publication of RaTG13 it was noticed that the two were the same virus. Shi finally admitted that they in fact were the same virus and she had changed the name without citing her earlier publication. Shi also admitted to the copper mine cave incident and all of her expeditions to the mine. In December 2020 Shi also revealed that there were 7 other SARS-like viruses from that mine that had not been published and she was not sharing. I would love to see Alina Chan cross-examine Shi, Baric and Daszak in a court room or hearing.
Correction: I meant to say the mine is in Yunnan, China. Also, this mine was blocked from reporters or outside investigators, including the WHO. This is the location most likely to provide answers to natural origin, yet the Chinese are hiding and covering it up. Why?
Interestingly, there were actually two thesis’s on the 2012 Yunnan incident, the second a doctoral thesis by the current head of the China CDC, Robert Gau, who is also the one who cleared the Hainan wet market as being connected to the origin of SARS-Cov2 in the spring of 2020.
Ron,
Why do you think that a number of scholars who initially thought that there were some suspicious properties of the virus seem to have now shifted towards regarded a zoonotic spillover at the market as being more likely than some kind of lab leak?
What about this paper that seems to suggest otherwise?
https://www.sciencedirect.com/science/article/pii/S1873506120304165
Anders –
You beat me to it. It’s fascinating how often you see what Ron just said repeated.
In fact RickA said it above (apparently since deleted) and I responded by asking about his skepticism, here:
https://andthentheresphysics.wordpress.com/2023/03/13/the-origins-debate/#comment-216847
What’s most interesting to me is the “meta.” Why do we see, as with discussions of climate change, these patterns play out? Of course, the patterns are not only among “skeptics” but it is particularly interesting to see the patterns
play out among people who consider themselves skeptics.
The manner in which the patterns overlap between climate change and the origin debate is, imo, quite interesting.
Another link:
https://www.frontiersin.org/articles/10.3389/fmicb.2021.649314/full#:~:text=Four%20coronaviruses%20with%20furin%20cleavage,and%20is%20marked%20in%20blue.
Sorry – I see now that it wasn’t Rick
A who wrote that taking point, but it was contained in the article he linked.
The pattern nonetheless stands.
I thought this other article was interesting also – as it gets to another aspect of how the often repeated, and non-skeptical argument about the FCS, captures the patterns of “narrative surfing” we see in these kinds of public discourse about scientific controversies that become politicized.
https://www.news-medical.net/news/20210217/The-origin-of-SARS-CoV-2-furin-cleavage-site-remains-a-mystery.aspx
My point being, (it is my understanding that) even if the FCS was unique to SCoV-2 among coronaviruses, that wouldn’t necessarily imply it wouldn’t be a natural adaptation through well-known evolutionary processes of recombination.
Of course, I understand nothing of the technical issues in play…
But the amplification of these talking points throughout the public discourse is fascinating.
It would be more interesting if it was not the same for just about any online debate that reaches The Discourse, J.
If we return to the paper you and Rick made us read, there are two hypotheses regarding the lab leak.
First is that it leaked emerged from a CoV lab. Were it true, researchers would see a signature of it somewhere. Yet the furin cleavage site (FCS) is intact. Also, researchers would expect adaptative markers from the animal models used to develop the virus. They found none.
Second is that it is engineered. This has presumably been refuted. Researchers found no trace of deliberate engineering. They also have discovered a relationship between the strength of the FCS and the virulence of a virus (I suppose the concept of virulence comes from that kind of situation) that they did not know at the beginning. Which means it would be hard to engineer something unknown at the time. And the same problem about the absence of signature applies.
To answer JCH, this does not mean we can exclude a lab leak. From a series of absence of evidence we cannot rule out an eventual presence of evidence. But so far no cookie for our Freedom Fighters, book deal notwithstanding.
ATTP: “What about this paper that seems to suggest otherwise?”
I was aware of the FCS being in other coronaviruses, as the paper outlines. It is nevertheless still true it has not been found in the wild in any SARS virus, the sub-genus Sarbecovirus. Research by Eco Health showed that the bat viruses had very little crossover even within bats of different species in the same caves. They are very specific. This, even though it was found that bats are commonly co-infected with different coronaviruses, which is the mode for new variants through recombination. The conclusion was surprising how slow nature worked to evolve change. Labs do it much faster.
Here is a link to the December 2020, Nature addendum to the Jan 2020 Shi paper authored by Zhou. https://www.nature.com/articles/s41586-020-2951-z).#:~:text=Between%202012%20and,publication1.
Here is the original article.
https://www.nature.com/articles/s41586-020-2012-7%EF%BC%89%E3%80%82
Sorry for the string of comments but I thought one more…
From that article I linked:
However, within the betacoronaviruses of the sarbecovirus lineage B, this type of site is unique to SARS-CoV-2.
> how slow nature worked to evolve change.
Let me guess, Ron: you just found this thread and have not listened to the podcast episode this thread is about, right?
Joshua, you might like Ron’s explanation for the correlation between COVID contrarians and AGW contrarians:
https://rankexploits.com/musings/2023/interviewing-chatgpt-on-why-it-seems-to-lie-and-bs/#comment-219680
I will spare you the red baiting at the end.
Very clever, young man. Very clever. But it is Freedom Fighters all the way down.
Willard –
I would like to say that you made me look. But of course I know that’s a broken explanation.
After some weeks at the AirVent, I’ve finally decided to (mostly) not look anymore.
But because you made me look 😝, I’ve been reminded of the reason I’ve decided to not look. Here, a bit further down at Lucia’s (honestly, I mostly looked because I find the idea that people think that ChatGPT “lies” to be interesting), I found the inspiration to remember to not look.
The fact that many people choose sides based on Team Red or Team Blue does not mean that both sides are equal. In both these cases Team Blue is promoting probably falsehoods while Team Red is on the side of truth, even if for the wrong reasons.
My latest lens through which to view all things climate wars and other standard fare in online discourse, is the fundamental attribution error. Mixed with a failure in cognitive empathy. Combined, I think they explain much.
I find it depressing that good faith interrogation of issues is such a weak signal amidst all the noise. I scan Twitter and podcasts to find anyone who can make good faith arguments. Believe it or not, I find the best place to look is sports podcasts.
I go back and forth over whether it’s worse than it ever was. Conspiracy theories about a “lab leak” of Ebola in Sierra Leone, and vax-caused AIDS, feel like they signal some shift on the world.
But then I remember, the difficulty of engaging with these kinds of issues, that surfaces as conspiracy beliefs and “lab leaks,” is at least as old as any vaccine, as old as Frankenstein.
The fundamental attribution error is,
well, a fundamental component of human nature.
But that doesn’t mean that cognitive empathy isn’t fundamental.
If only I could find some!
, but as Mosher points out, left over grant money is typically used to start research for the next grant proposal
you can also get paid twice for the same work, if your smart
“Let me guess, Ron: you just found this thread and have not listened to the podcast episode this thread is about, right?”
Willard, since you spend your day lurking at Lucia’s you already know the answer. You are a great detective and are correct that I have not yet listened to the podcast. Perhaps you can answer for me if they brought up the points about Zhengli Shi forgetting to mention in her Jan 2020 paper on SARS2 origin that RaTG13 came from a mine associated with 3 people of dying with the exact strange pneumonia symptoms referenced in her paper, including the ground glass xrays.
Did the podcast mention why Daszak covered up about his PREDICT grant proposal regarding the FCS, which clearly he turned out to be right on the money. His prediction came true and the government should have been sorry for turning down his proposal. He surely was thinking the government could have saved millions of lives and prevented endemic Covid by sounding the alarm early. If they had just listened to him everyone would have known what to watch for to quash it. Instead he and his researchers remained quiet. I suppose they were worried that people might suspect the wrong thing.
This is similar to the story of a murder suspect that said he was nowhere near his murdered wife and son until the police produced his son’s Instagram video that had the father’s voice in the background minutes before he and his mother’s murder. The father said he had initially lied because he knew people would get the wrong idea but that he was innocent. The jury used Occam’s razor and unanimously came to a simpler explanation in a very short deliberation.
Ron,
You are too kind. I only looked back at what prompted you to pay us a visit. Besides Doc’s plug, I noticed your last comment.
Please rest assured that your JAQing off has reached its limit. When you will listen to the podcast episode, I will see what I can do.
Oh, and do not think I forgot our little antivax episode at Judy’s.
“To answer JCH, this does not mean we can exclude a lab leak. From a series of absence of evidence we cannot rule out an eventual presence of evidence. But so far no cookie for our Freedom Fighters, book deal notwithstanding. …”
I accept it is plausible. Always have. It’s nuts to believe it happened.
[Manual pingback. -W]
Okay, you could have mentioned there is 35 minutes of introduction and disclaimer, but I finally got to Mike, Eddie and Kristian (can’t tell them apart yet), and I need to post as I go because otherwise it would be too long. They’ve said that BSL4 makes no difference because they used BSL2 protocols. This is true but I did not hear any virologists bragging about BSL2 protocols until it was revealed in May 2021 by Nicholas Wade that the Eco Health grant for the chimeric SARS virus experiments were to be under BSL2.
They next say Wuhan was not unusual because there are BSL2 labs all over China and bats in Hubei Province all around them with SARS viruses. This is not nearly a fair representation. There is only one lab where the Bat Woman was the director and who was doing gain of function on SARS. The 95% of the relevant bats and viruses are hundreds of miles south of Hubei. The only area associated so far with viruses similar to SARS to are in Yunnan and across the border into Thailand. The virus that is most like SARS2 (that we know of) came from a particular site near Mojiang in Yunnan where three oldest of six ill-fallen workers died with an atypical pneumonia that from the two thesis’s we now have is startlingly similar to Covid. As I mentioned, this was all top secret. Shi carried thousands of virus samples back to the WIV and made at least one expedition per year, if not two, to this site after the 2012 incident. In the coverup of the origin of RaTG13 Shi claimed that it was an oversight that she committed self-plagiarism by not referencing Bat-cov4991. When asked for an explanation she said it was renamed in 2018 when they received new equipment allowing them to do PCR and sequence the entire genome. Before that Shi had only published the RDRP RNA sequence. Shi claimed that the last sample was exhausted in doing the PCR, which makes no sense, as even lay people here should understand that PCR multiplies the RNA indefinitely. But without an actual sample there is no way to prove if any edits were made in Shi’s presented RaTG13. How convenient.
Maybe Mike, Eddie and Kristian get to this. I’ll let you know.
They go on and claim: “If there is any place the Chinese one would expect it to would be the live animal market because like SARS1, that is where they were selling particular wildlife animal species we know are reservoirs for the virus. ”
This is false. As I wrote before, Eco Health’s own field studies show that civet cats, pangolins and racoon dogs are not natural reservoirs for ANY types of coronavirus, not barring just SARS-like ones. Thus there is no opportunity for recombination or human zoonosis. The only animals found with SARS viruses were ones in illegal captivity. They also did not mention the obvious circumstance to me which is that since it is known (or was thought to be known) that SARS1 was from a wet market, that would be the natural place for the cover up to try to misdirect the expected investigators to.
>…that would be the natural place for the cover up to try to misdirect the expected investigators to.
Lol. Perfect.
You always know there’s a conspiracy when you attack people of conspiring and they deny it.
Any place that might be the most likely location of a spillover is the most likely place for conspiracists to use as a cover.
The unfalsifiability of the arguments are always a given. All you need to do is start with full confidence that a conspiracy exists and then you can prove that a conspiracy exists.
It’s just like with Ron’s beliefs that vaccines cause autism; the fact that he knows people are lying is what confirms that there’s a vast conspiracy to hide the links between vaccines and autism.
It’s always the same.
And, of course, even if we didn’t have proof Ron provides by just knowing that people are lying and picking the most like spots as a coverup, we would also know that all of this is true because “the left.”
Like Joshua, I am finding that these three pre-eminent virologists are first and foremost psychologists. They sound exactly like Joshua, attacking people, not arguments.
Kristian presented a false representation of Ridley and Chan’s writing on the 8 unpublished RatG viruses. They never claimed that one of them was SARS2. Quite the opposite, they say the existence of the 8 unpublished viruses does not preclude a ninth top secret never to be published virus. And, the only reason that they had to admit to the 8 was they knew they had been submitted for publication prior to the fall of 2019 Chinese embargo on cooperation and shut off of the online database.
At least one of the three virologists had to know this or Chan and Ridley’s point. So they are clearly dishonest there and also covering up important background circumstances to the public.
Also, there is no reason the 8 viruses’ publication should not have been accelerated in light of the pandemic other than, like with the lack of disclosure of RaTG13 being the same virus as bat-cov4991, they were just slowing down the investigation. Anderson goes on, “For me it’s such a litmus test that if your frame of mind is that they are hiding everything [they’re all paranoid], and then they show you the evidence and it’s really trivial and completely unrelated, [referring to the 8 RaTG viruses]. They just move the goalpost and say whatever else are they hiding.” He points at Alina Chan.
But Anderson never stops to wonder why in the world would any scientist want to be holding any cards to the chest on SARS2 in 2020 to present. That makes no sense.
I criticized your logic. Except to the extent that your logic is consistent across many different conspiracy theories – at that level it might be considered a criticism of you as well as a criticism of your logic.
On the other hand, your arguments contain accusations of lies, coverups, etc. throughout, and all the way down.
What remains unknown (to me) is whether what you do, the reversal of reality, is deliberate or somehow for some unexplainable reason just unaware.
[Peddling. -W]
I think you should keep the remaining of your conspiracy ideation at Lucia’s, Ron. Unless you want to send it to Lew directly. But before you do, if you could provide a quote to support that incongruous claim:
that would be great.
Thanks.
[Playing the ref. -W]
Just a general comment, which may be related to some of what Joshua has highlighted. If your position involves assuming that quite a large number of people are lying, or covering something up, or ignoring that others are lying, then maybe it’s worth taking a step back and considering how much it would take to be more charitable. Alternatively, at least acknowledge that you’re suggesting that there is some kind of conspiracy, because this seems to be the definition of a conspiracy.
“We know this thanks to a Twitter account known as The Seeker”
Conspiracy ideation: it’s not just for climate change
It’s simultaneously hilarious and sad that the same people who are quite unable to do basic arithmetic on climate change but nevertheless believe they know better than actual experts now also see themselves as brilliant forensic virologists.
Exploring the reasons and drivers of such hubris and how social media amplifies and encourages it would be more interesting than the fisking of their amateur microbiological musings.
Best not to start comments with an oxymoron, Ron.
I presume that research Mosh allegedly referred to was federally funded.
It’s a criminal offence to keep leftover Federal grant money and spend it on other research. Researchers have gone to federal prison for it, even over relatively small amounts of money and where they made no personal profit.
I doubt if it’s remotely common. The stakes are too high.
The Seeker. Truth Social. German Democratic Republic.
What do these three have in common?
Ron, the third way to look at it is that conspiracy theorists do love their conspiracy theories.
NASA faked the Moon landings, therefore climate change is a hoax and SARS-Cov2 was engineered in a Chinese lab.
> The Seeker
You can call him Prajensit, Dave.
ATTP: “If your position involves assuming that quite a large number of people are lying, or covering something up…”
I think you are confusing conspiracy with bias. Having a common bias is not criminal, its human. So using the accusation of bias to silence their opinion is done under the assumption that the censor can’t be biased. If that is granted you really can’t trust any debate to be objective or informative.
All five of the men on your podcast stipulated a priori that the Chinese government is completely untrustworthy and covering up, not even willing to admit the virus could have come from the Hainan Food Market because they are unwilling to admit the virus originated from China. Is that accusing people of conspiring or lying? No. it’s recognizing reality. But your argument for stopping speech that contains dissenting facts is exactly the one used by them and many others. The enlightenment of free speech and open debate is fleeting.
Ron,
No, I don’t think I am. Intentionally doing something wrong (lying) in order to avoid people finding out the truth, is essentially a conspiracy.
I would argue that this is still essentially a conspiracy.
I’m not arguing for stopping speech that contains dissenting facts.
The podcasters assume that the Chinese government can’t be trusted and also that Chinese scientists are not free to express their true opinions or reveal undesirable facts. This is also what Ridley and Chan’s write in Viral. But I don’t understand the podcaster’s logic of why we need to trust the Chinese and the Chinese scientists on all the information that has flowed to this point. The vary assumption that they are revealing the first known cases has contradicted by a stack of evidence in Viral. In fact, studies of blood donation and sewer sludge show the virus being detected in samples from the US in December 2019, before the Chinese were admitting person to person spread. Italy and Spain show infection in their samples even earlier in 2019.
angech says:
March 28, 2023 at 12:28 am
[Manual pingback. -W]
thanks for leaving the clickable link ,W
If there were real evidence as claimed,
“FBI Director Christopher Wray says the agency has assessed that a leak from a laboratory in Wuhan, China, likely triggered the COVID-19 pandemic,
The FBI director says he couldn’t share many details of the agency’s assessment because they were classified
“The FBI has for quite some time now assessed that the origins of the pandemic are most likely a potential lab incident in Wuhan,”
–
Then the FBI would be grossly negligent in not disclosing this fact quite some time ago for everyone to shape up and act on.
How an agency working in the USA could know what happened in a foreign country is a mystery unless they had USA lab connections with the Chinese labs.
We will never know.
Where’s the evidence for this?
Also, if this is clearly true, why are experienced scientists who work on this topic still arguing that the origin was early December in the Huanan market?
ATTP, thank you for allowing me to present dissenting facts then.
Here is a paper that uses the Twitter revealed masters thesis to analyze whether the 2012 Mojaing miners incident was a SARS infection.
They go into the medical evidence, including the unique ground glass chest radiological pictures. They have four other paragraphs of similarity and then a list of questions that remain unanswered to this day that I will explore if allowed.
Okay, I did find this.
https://eu.usatoday.com/story/news/factcheck/2020/07/07/fact-check-coronavirus-found-march-2019-wastewater-sample/5350878002/
So, could be real, could be contaminated, could be a false positive. One question might be how did a highly transmissible virus end up in the samples despite there being no obvious outbreaks in these regions?
I have been scanning through hundreds or hits on wastewater surveillance papers of SARS-COV2 looking for the paper I remember. I am not sure if yours is the one. Here is another that finds SARS2 in Italy in December 2019.
I don’t know the science that well to say whether the papers can be wrong. There are several. I just saw another paper that detected it in Brazil in December.
I would go back to thinking about the pangolin SARS analysis. What are the chances that they found a pangolin with a virus not found in the wild that was adapted to its species, and very the RNA being more similar to SARS2 even than RaTG13? The only reason the Pangolin theory did not fit was that the all important 2 spike proteins were way different, and RaRG13’s more similar that it to SARS2.
‘Being truthful is essential’: scientist who stumbled upon Wuhan Covid data speaks out – Florence Débarre’s discovery of genetic data online showed for first time that animals susceptible to coronavirus were present at market
https://www.theguardian.com/world/2023/mar/28/being-truthful-is-essential-scientist-who-stumbled-upon-wuhan-covid-data-speaks-out
First, do no harm – the sickening length of this argument, drawing in those who insist their conspiracy theory is correct and have nothing better to do (on wasting time, guilty as charged) are continuing to raise the temperature of an already fraught society. This is a serious distraction from doing our best in community. So much easier to indulge in finding somebody to blame, right or wrong.
> But I don’t understand the podcaster’s logic of why we need to trust the Chinese and the Chinese scientists on all the information that has flowed to this point.
I don’t understand why Ron hasn’t clarified whether he’s stopped beating his wife.
The presence of SARS-CoV-2 RNA in human sewage in Santa Catarina, Brazil, November 2019
Alina Chan in scrutinizing the pangolin SARS papers on the two reported cases noticed that there was overlap between the coauthors on each of the papers. She then noticed that the RNA sequence raw data of the second case in the fall of 2019 was identical (plagiarized) from the original case in March 2019. There was only one case. Why would an author allow his coauthors to plagiarize him? Hold on before you delete this. Remember, Eddie, Mike and Kristian agree that China is not trustworthy.
My conspiracy theory is that the pangolin investigators were paid to have another case show up. The competing theory is that the investigators independently falsified a second case on their own initiative to make the first one more important I suppose. If my theory is correct then it shows that the China authorities were laying a misdirection for the origin of SARS2. In fact, in early 2020 there was a blitz of Chinese papers postulating the pangolin origin theory. It was western virologists that shot it down on the RNA evolutionary inconsistency I pointed out.
So putting on your conspiracy cap just for the sake of argument.
[Snip. Just Asking Questions. -W]
My conspiracy theory is that the pangolin investigators were paid to have another case show up.
You are not a polymath genius. What attracts you to such definite opinions on conspiracy theories and other contrarian positions across multiple technical areas where you have no expertise to judge?
This is a serious question, and much more interesting than your latest conspiracy theory!
Ron,
You still haven’t given me the quote to support a claim that is pure gibberish, and you are still spinning wheels on your conspiracy ideation.
Give me a quote. From the book.
Here’s the issue with this discussion. None of us really have the expertise to have an informed view about this. We can all find papers/articles that appear to support our views, but probably don’t have enough expertise to assess them in detail. So, trying to have a detailed discussion about the actual evidence doesn’t really make sense to me; we’re not going to resolve our disagreements by interrograting the evidence.
Joshua, as I mentioned, I loaned out my copy of Viral. But here is Alina Chan’s analysis in a long Twitter thread: https://twitter.com/Ayjchan/status/1320345474646290434
Here is her first Tweet in the series:
A few tweets down:
> I loaned out my copy of Viral
How convenient.
Putting my conspiracy hat on for a moment, I’d say you don’t want to support your claim that they say the existence of the 8 unpublished viruses does not preclude a ninth top secret never to be published virus, clarify what it means, or spell out the logic. That you’re too busy peddling your pet theory (e.g. by citing a 2020 tweet thread) to solidify the hook by which you introduced your peddling. Now that peddling is ongoing, the race is on.
Here’s the issue with this discussion. None of us really have the expertise to have an informed view about this. We can all find papers/articles that appear to support our views, but probably don’t have enough expertise to assess them in detail. So, trying to have a detailed discussion about the actual evidence doesn’t really make sense to me; we’re not going to resolve our disagreements by interrograting the evidence.
+many, and I refer you all back to ChatGPT’s useful input earlier in the discussion.
…people are exhibiting confirmation bias by seeking out and interpreting information in a way that supports their existing beliefs about the origin of COVID-19. This bias can make it difficult for people to objectively evaluate evidence and may contribute to the polarization of opinions surrounding the pandemic.
https://andthentheresphysics.wordpress.com/2023/03/13/the-origins-debate/#comment-216708
Anders –
> Here’s the issue with this discussion…
The availability of information has reinforced a belief where Googling or whatnot becomes “doing your own research.” In a sense that’s seems a valuable development. But the idea that Googling (without background expertise and relevant experience) = research is problematic. Then couple that with the reality that “expertise” is subject to biases and uncertainties, and throw in factors such as “replication crisis,” and problematically aligned incentive structures. And wrap that all up with polarizing ideological “motivations.”
And throw in crap like this:
But I don’t understand the podcaster’s logic of why we need to trust the Chinese and the Chinese scientists on all the information that has flowed to this point.
Which so well demonstrates the phenomena of fundamental attribution error and a lack of cognitive empathy as I described above (not to isolate Ron per se, these are ubiquitous problems, but he frequently provides such juicy examples and as far as I can tell is never willing to hold himself accountable – which makes his comments valuable).
So we get what we’ve got with the origins of SCoV-2 and Ivermectin and Hydroxychloroquine and “lockdown deaths” and “masks don’t work” and the “plandemic” and “vaccines are causing excess deaths,” and on and on.
And of course we’ve all been watching how very much the same pattern has played out over decades with climate change.
I look forward to the day when we can all just turn all of this over to general artificial intelligence.
I’m sure that will work out well..
Also, AT, whilst I’m certainly not qualified to judge the evidence myself, it’s pretty clear that the evidence one way or the other is weak; low confidence is given to the conclusions of the various investigations, and many people who are qualified split in different directions or sit on the fence.
Given this it’s incomprehensible to me that someone *not* qualified in any way would hold a strong opinion on the matter.
But here we are.
So we get what we’ve got with the origins of SCoV-2 and Ivermectin and Hydroxychloroquine and “lockdown deaths” and “masks don’t work” and the “plandemic” and “vaccines are causing excess deaths,” and on and on.
My personal favourite was the insistence that Sweden was in herd immunity whilst cases were rising.
Very Tall,
I would call this particular form auditing bias.
Evidence is King. (Or Queen.) Evidence stands alone. No need to make explicit claims when one presents evidence. No need to make any coherent argument either.
As soon as you present evidence, it is relevant. No need to defend the evidence you offer. It stands alone. See above.
Evidence leads to so many questions. And we have so little time. So every time evidence is presented, only ask yourself: what else are they hiding?
For evidence is always evidence that something has been hidden from you. Why else have you uncovered it? As soon as you uncover evidence, a conspiracy to keep you in the dark has been revealed.
Evidence you can find in personal emails counts for double. However banal the information is. Even if the correspondents are already on record.
The truth is out there.
Aha, Willard, I see that you have admitted that evidence is King.
What other admissions should we expect from you?
Willard and ATTP, the overall logic is this: Eddie, Mike and Kristian assume for their wet market origin analysis that the data is trustworthy a priori. That assumption relies on the trust in Chinese government diligence in identifying the novel virus at the outbreak as well as their dutiful supply to the world of that data. Forgetting the mountains of evidence of prior spread in other countries and reticence of China to share data with the world, the podcasters ask the question to the scientists before them, “Why does China not have the same conclusion of the wet market being the origin.” The podcasters then answer their own question by pointing to the mountain of evidence that China isn’t forthcoming or trustworthy. The scientists did not even have to open their mouths. I doubt they could get away with that anywhere but here of other friendly audiences.
Does this mean that we can’t analyze any evidence? No. That would mean we can’t use any statements that defendants make in earlier versions of their story. Once you open your mouth your statement can and should be fair game unless you confess that it was wrong or deceptive later.
Speaking of looking at early statements, Ralph Baric, when interviewed on the first couple days of Jan 2020 asked the reporter here about the age of the people dying. From Menachary (2016) Baric knows that new SARS viruses kill the older animals first. One can just feel the pit in his stomach.
VTG –
> My personal favourite was the insistence that Sweden was in herd immunity whilst cases were rising.
That was a nice one. But again it just reflects the same larger pattern: people Googling and looking at trend lines on their computer screens to interpret epidemiological data when they’ve never, ever, done any related work before, and lack any relevant expertise or related experience, during an ongoing pandemic with a novel virus, and without any systematic regard for myriad confounders, to reach confidence conclusions, at a website where appealing to uncertainty is supposed to be part of the mission!!!
And yes it can be fun to focus on climate change “skeptics;” it was too perfect to see “early herd immunity” become such a widespread article of faith over at Judith’s, as proof of the tyranny of “woke experts,” and to see Nic, in particular, extrapolate from his “toy models” without due consideration of his “priors.”
I remember when at Judith’s it was a widespread article of faith that Googling and some measure of mathematical sophistication showed a conspiracy whereby the polling prior to the 2008 election was being “skewed” by “woke” pollsters to exaggerate Obama’s popularity so as to enhance his chances of victory.
Never mind that actually, Obama outperformed the polling in the end. And of course, never any accountability.
But I really do think it’s unlikely that “skeptics” are really anomalous in some fashion along these lines. These are all ubiquitous patterns rooted in human cognition and psychology. For all the study of these kinds of psychological tendencies and cognitive biases, I don’t see reason to think that these tendencies are distributed disproportionately across political or other ideological dividing lines.
I will say that one thing I’ve been wondering about lately…after spending a few weeks observing the AirVent, and seeing a complete confidence there about how “the left” is fundamentally flawed…having spent time at Lucia’s in the past also, has shown me that fundamental flaws on “the left” is frequently offered as causal for these patterns.
I don’t quite see the same level of blaming these phenomena on “the right” here, at least (not that it doesn’t exist to some extent). Maybe observer bias or maybe sampling bias. And it runs counter to my theoretical starting point that there shouldn’t be differences aligned with grouping (and that the tendency to see such differences is an outgrowth of the underlying psychology and cognitive biases)…
/soapbox
Ron –
That assumption relies on the trust in Chinese government diligence in identifying the novel virus at the outbreak as well as their dutiful supply to the world of that data.
It’s remarkable how you keep repeating this. It’s clearly wrong, and nothing other than an invention of your imagination – presumably a function of your inability to get past a fundamental attribution error that results in a lack of cognitive empathy (ok, Willard, I’ll stop repeating that now). And yet you double down.
It only provides a window into the flaws in your reasoning process: you start with the existence of a conspiracy, then invent a non-existent behavior, then attribute that non-existent behavior in such a way as to confirm your belief in a conspiracy.
You do this over and over, across many different contexts (vaccines, Douma, etc.).
As an exercise, consider the possibility that they don’t “trust” the Chinese government diligence,” and then see if you can figure out another way to understand their behavior.
> Eddie, Mike and Kristian assume for their wet market origin analysis that the data is trustworthy a priori.
I don’t think so, Ron. And I listened to the episode two times now. I also read all the comments on this thread, and most if not all the papers cited. And I also read other stuff, but you know ninjas – they tend to keep their cards close to their chest.
Let me show you what I see. Here is you:
[R] Okay, you could have mentioned there is 35 minutes of introduction and disclaimer, but I finally got to Mike, Eddie and Kristian (can’t tell them apart yet), and I need to post as I go because otherwise it would be too long.
Here is me, previously:
[W] You can start the podcast at the 45th minute. The BSL4 and other minor red herrings are covered, preparing for the argument that a lab leak springing out of a faraway wet market would be an unlucky event.
So let me put my conspiracy hat another time:
Doc pinged us. You jumped in with your pet theory. Once you got baits, you rushed into action. And as you’re rolling, it does [not] matter much if what you say makes any sense. It’s sugarcoating. Evidence is King, and you are laying it thick.
And then comes the questions you ask.
I tried to slow you down a bit, and take a moment to at least try to be relevant. You did, at least for the time you wrote your first comment in response to my first request. And now you can’t meet my second one, as you lent the book.
Here’s my theory – you can’t defend the book you came to defend, so you go all in, peddling evidence and asking questions unrelated to the podcast episode, and not exactly providing receipts for the book.
Am I warm?
Willard, are you saying we should accept that the Chinese reporting on what they presented as complete and accurate? If not, these virologists are finding the breadcrumbs that were left three years ago, bread crumbs the Chinese don’t even want to endorse that this point, (for unknown reasons).
[Playing the ref. -W]
Ron –
> Willard, are you saying we should accept that the Chinese reporting on what they presented as complete and accurate?
Jesus.
Ron,
No, I’m not saying anything regarding what you’re trying to peddle right now. You really should keep that kind of tricks for Lucia’s or Judy’s.
Let me show you some evidence:
I’ve written this on 2023-03-14.
That’s more than a week ago.
Slow down. Take your time. Listen to the episode. Get your book back. Provide the quote.
Then we’ll talk.
Willard, I agree precisely, let’s take baby steps here. How does one accept the case data and marketplace sampling supplied by the same people that you don’t accept anything else from at face value?
[Just Asking Questions. -W]
Ron,
Baby steps are not enough. You got to follow the points being made. I made two.
The first is that the Questions you are Just Asking are mostly irrelevant. The second is that I just showed you evidence that directly contradicts what you said about the interviewees, whom you could not distinguish. I could add a third point – if you add more than one question per paragraph, chances are that you’re not taking baby steps.
If some authority A denied that the photos you took of a market existed, would you trust A? I wouldn’t, and I’m quite sure you wouldn’t either.
So your premise is plainly wrong.
The evidence analyzed does not come from any Chinese authority anyway. You’re just into “But China, But China, But China” mode. Same as in Climateball.
It’s likely we will never absolutely know. My personal view is that the FBI and DoE are motivated by the desire to create an appearance of fairness for political reasons – going along to get along, an old standby, particularly troubling when it comes from Biden. But the ongoing controversy is feeding ignorance, violence, and blame. That’s why I posted the extract above. It seems those who have the biggest stake are insistent on promoting gain of function, which is the least likely by some considerable margin. This is why I’m still bothering to show up here.
Please stop the violence, not just personal violence, but violence towards the scientific project, and the search for individuals who are the opposite of blameworthy to blame.
I agree with you, Susan. The violence toward science is of a piece with the violence against any type of enlightened and tolerant world view. There appears to be a joy in anger, in opposition to any sensible secular public policy… a joy seems to be taken in offering up death and destruction like such things are a common good. These are strange times. I think we have to keep offering up an honest conversation about our collective experience and our hopes and plans for the collective experience that lies ahead of us. https://www.hup.harvard.edu/catalog.php?isbn=9780674768680
small –
> a joy seems to be taken in offering up death and destruction…
I’m going to disagee that this is an attack against the scientific enterprise, or a joy from death and destruction, that’s differently distributed across ideological viewpoints, as manifest in views on issues such as the origins of SCOV-2.
Whenever I try to discuss matter such as the the origins at places like Judith’s, I have Ron and like-minded folks line up to explain how my views can be explain by the evil and stupidity or whatever, of “the left.”
I just saw a tweet from a prominent LL proponent who compares virologists to Nazis.
I think there are more banal reasons for why these kinds of antagonism and polarization develop.
The idea that ideas are violence is giving validation to Orwell’s proposal of thoughtcrime. Blame and accountability are not violence either. Each thing can facilitate another but that is not the same thing. Accountability is seen as a good even though it can facilitate violent retribution which is bad. The reason is that accountability implies rightful consequences after the truth is known. Truth is about the only universally agreed upon value, likely because a world of lies leaves us all lost and defenseless except to resort to physical defense which also rationalizes pre-emptive violence.
[Playing the ref. -W]
> The idea that ideas are violence
It’s more the idea that speech acts could be, and George knew it:
https://en.wikipedia.org/wiki/Two_Minutes_Hate
Willard, on the photos, I’m not evading your question. I just don’t understand what you are asking. Photographic evidence is as trustworthy as the origin of them and the stakes involved, obviously, like every piece of evidence. My way of determining the validity of a theory is if it solves all the outstanding questions satisfactorily.
[More peddling. -W]
Honestly Ron, your constant and voluble demonstration of your own lack of insight, combined with a tedious search for conspiracy all wrapped in endless victimhood is strata upon strata of ennui.
Sorry to be so frank but you really, seriously need to get over yourself here.
Neither you nor I are important in this. Neither of us bring any new evidence or analysis. Admit your own irrelevance and free yourself from your pompous questioning, for the love of God.
verytallguy:
I am also not important in this. But there is nothing wrong with sharing links and speculation – even if we are all just laypersons to virology. Everybody gets to share their thoughts and speculation and opinions – not just scientists.
Speculating is great Rich.
I speculate what kind of person you are.
Just asking questions is good too.
How often do you beat your wife?
Why don’t you answer these questions?
My theory is you have something to hide.
Who pays you to hide these answers Rich?
Etc etc etc ad tedium ad nauseum.
The only good news here is I lack Ron’s stamina to continue, for literally years
Ron,
You said that Matt & Chris’ guests assume for their wet market origin analysis that the data is trustworthy a priori. You also raised many concerns by asking leading questions, for instance are you saying we should accept that the Chinese reporting on what they presented as complete and accurate? I duly submit that you are trying to suggest that these virologists are useful idiots that gobble anything China says.
They’re not. In fact they’re better placed than you to understand the pressure researchers face when dealing with that autocratic regime. For instance, one of them has been slandered for photos he took.
There are more on that theme circa 1:15.
So I think I’m making a fairly straightforward argument. If you don’t understand it, why should anyone trust you to present or even understand the evidence from a book you do not have in your possession right now? Please report when you get your book back.
Meanwhile, enjoy this argument:
https://www.theguardian.com/books/2021/nov/15/viral-by-alina-chan-and-matt-ridley-review-was-covid-19-really-made-in-china
Since I independently made the same argument earlier in the thread, I might be biased.
That’s a good article, Willard.
> yet although following the Sars outbreak numerous animals tested positive for sibling human viruses, in the case of Sars-CoV-2 scientists have yet to turn up any evidence of prior infections in animals.
Might be worth noting… my understanding is that there hasn’t been a direct ancestor virus found in animals but they’ve come close with bats, civets (“as good as you can get,” said Holmes)
> But as every schoolboy knows, absence of evidence is not evidence of absence – it may simply be that samples have yet to be taken from the right animal.
Right. And admittedly the known potential ancestor is closer for Sars1, but it’s interesting that lab leak proponents generally accept the lack of evidence with Sars1 but are like a dog with a bone with the lack of evidence with Sars2.
One might argue that a commitment to a lab leak theory might help explain that difference – but more likely it’s just a pure coincidence of some sort. 😉
Sorry –
Needs an edit –
Might be worth noting… my understanding is that there hasn’t been a direct ancestor [Sars1] virus found in animals but they’ve come close with bats, civets (“as good as you can get,” said Holmes)
Laos:
“Abstract
… SARS-CoV-2 progenitor bat viruses genetically close to SARS-CoV-2 and able to enter human cells through a human ACE2 pathway have not yet been identified, though they would be key in understanding the origin of the epidemics. Here we show that such viruses indeed circulate in cave bats living in the limestone karstic terrain in North Laos, within the Indochinese peninsula. We found that the RBDs of these viruses differ from that of SARS-CoV-2 by only one or two residues, bind as efficiently to the hACE2 protein as the SARS-CoV-2 Wuhan strain isolated in early human cases, and mediate hACE2-dependent entry into human cells, which is inhibited by antibodies neutralizing SARS-CoV-2. None of these bat viruses harbors a furin cleavage site in the spike. Our findings therefore indicate that bat-borne SARS-CoV-2-like viruses potentially infectious for humans circulate in Rhinolophus spp. in the Indochinese peninsula.”
A follow up on “Conspiracy theories? What conspiracy theories?”.
“Similarly, multiple lines of evidence show that before the coronavirus disease 2019 (COVID-19) outbreak in Wuhan Huanan Seafood Wholesale Market, sporadic positive samples and cases of SARS-CoV-2 appeared in many countries and regions. … In a preprint of The Lancet released on August 6, 2021, Amendola and colleagues collected 435 oropharyngeal swabs and urine and serum samples from 156 individuals with morbilliform rashes and tested them for SARS-CoV-2 infection by PCR, Sanger sequencing, ELISA, and SARS-CoV-2 plaque reduction neutralization assays. The first positive result of SARS-CoV-2 RNA was found in a sample that was collected in September 2019. Researchers estimated that SARS-CoV-2 progenitors emerged in late June to late August 2019 (26). These results confirmed that the virus had been prevalent in Italy before the official announcement of the first confirmed local COVID-19 case on February 21, 2020.”
So before SARS-CoV-2 leaked from the Wuhan Institute for Virology to the market in Wuhan, it leaked to Italy, which is also close by.
Apparently mahjong is very popular in Italy, Spain, and Brazil.
JCH, a Sci Am article that I linked to about Zhengli Shi said she found a 97% similar virus to SARS1 in Shitou Cave in Yunnan in 2015. The Laos SARS viruses I think are similar to SARS1. The big deal about SARS2 is that unlike SARS1 it appeared on the scene with a FCS and also well adapted to humans. One example of that is the codons for one arginine making up the FCS was CGG, an extremely rare codon for bats, occurring only in one other instance in the whole genome of SARS2. But it is the most common codon for arginine in humans and thus is readily available in biolabs.
Here is a Nov 2015 This Week in Virology interview with Baric and his top investigator, Vineet Menachery, on the chimeric SARS virus research partnered with the WIV on the NIH grant. https://www.microbe.tv/twiv/twiv-364/
They cover the experiment in the first half and the greater purpose and dealing with getting around the obnoxious GOF moratorium in more in the second half.
JCH, I posted this morning on studies that showed the wastewater analysis in many countries showed early spread of SARS2. You say it was a progenitor. I don’t remember that conclusion. Do you have links?
Was that Amendola 2021 preprint, proportedly to The Lancet, ever published in The Lancet or anywhere else for that matter or even accepted elsewhere for that matter?
How many SARS-Cov-2 preprints were ultimately rejected?
My own d-e-e-e-e-e-p investigation suggests no and alot! Stay tuned for further breaking d-e-e-e-e-e-p and original insights from this intrepid Internet detective also known as The Truthierest. 😀
It’s so surprising that’s virus that causes a pandemic would be “well adapted to humans.”
Appears to be published:
https://www.sciencedirect.com/science/article/pii/S0013935122013068
The cycle is complete:
March 13, 2023 at 8:15 pm
JCH,
So just like a computer virus then, or should I say two computer virii (not true spellink but I am The Truthierest! whom just makes stuff up as I go along)?
A zero-day with predetermined release dates. Neat.
The paper does suggest that otters confirm their findings. So I await further confirmations from otters.
Amendola, et. al. appear to accept the early origins hypothesis. Meaning something that predates the currently understood timeline.
@-W
“In other words, unless and until I see real bets, there is little to be gained from any of this. Except perhaps more notes for a next post on beliefs and bets?
I bet I could write it by the end of next week.”
I bet you haven’t.
I give 50/1 against you having finished it, but 2/1 on as odds you have around 70% sketched out.
There is something deeply funny about people with no real expertise in the subject throwing citations at each other in defence or offence of their preferred option.
I’d say its 1000/1 that ANY of us had even heard of a furcan cleavage before it came up in the spike protein of Covid-19.
And longer odds on anyone understanding the implications.
The odds on anyone finding the ‘True’ origin are incalculable, but that horse will never run.
The one that will is another pandemic virus, we need to learn from this one how best to react to minimise the damage. Not argue over origins.
In 1919 ‘Spanish’ flu came from a chicken producer in Kentucky. How would knowing that have changed the actions of health care ?
Willard wrote: “In other words, a zoonotic event is the null or default hypothesis; the onus is on Chan and Ridley to demonstrate otherwise.”
Remember, the controversy is that there was no scientific basis for there to be a default hypothesis. The natural origin theory was cemented by a manufactured consensus (behind closed doors) calling anything else a conspiracy theory. All should now admit that was the wrong thing to do regardless of what might turn up to weight one theory over the other. Mike, Eddie and Kristian are saying sure our deliberations were secret and we were split on the likelihoods at the beginning but that’s fine and we’re not hiding anything now.
JCH, this published Amendola paper has an army of co-authors from various institutions and looks pretty solid. They make it clear that the Wuhan strains (not progenitor species or strains) were found in Lombardy in October 2019, two months before the Hainan Food Market outbreak.
Amendola’s study of samples taken from rashes for measles surveillance confirms studies of wastewater collected prior to the Wuhan outbreak. They also point to Italy as one of the early countries. I believe China is using these to say the virus originated elsewhere, which is why they are not coming back to their wet market hypothesis and concurring with the NIH funded studies.
[Playing the ref. -W]
The Truthierest is all over this one, from the, have you stopped beating your spouse department, we have …
Waiting for the truth: is reluctance in accepting an early origin hypothesis for SARS-CoV-2 delaying our understanding of viral emergence?”
https://gh.bmj.com/content/7/3/e008386
“Two years after the start of the COVID-19 pandemic, key questions about the emergence of its aetiological agent (SARS-CoV-2) remain a matter of considerable debate. Identifying when SARS-CoV-2 began spreading among people is one of those questions. Although the current canonically accepted timeline hypothesises viral emergence in Wuhan, China, in November or December 2019, a growing body of diverse studies provides evidence that the virus may have been spreading worldwide weeks, or even months, prior to that time. However, the hypothesis of earlier SARS-CoV-2 circulation is often dismissed with prejudicial scepticism and experimental studies pointing to early origins are frequently and speculatively attributed to false-positive tests. In this paper, we critically review current evidence that SARS-CoV-2 had been circulating prior to December of 2019, and emphasise how, despite some scientific limitations, this hypothesis should no longer be ignored and considered sufficient to warrant further larger-scale studies to determine its veracity.”
Can anyone here answer their spousal abuse question? Why no answers to their “Out Of Africa” hypothesis?
@-RG
“the controversy is that there was no scientific basis for there to be a default hypothesis. The natural origin theory was cemented by a manufactured consensus (behind closed doors) calling anything else a conspiracy theory.”
The common factor in ALL new pandemics is a transfer from animals to humans that results in the evolution of a form that is transmitted from human to human.
All previous pandemic diseases have this zoonotic feature, there is nothing ‘manufactured’ about the consensus that this pandemic shares the same characteristic. It is the default hypothesis which will only be overthrown by convincing and comprehensive evidence that such a process is very unlikely and that an alternative is definitively established.
Like you, I do not have the specific knowledge of viral genetics to accurately judge any of the various speculative ideas that are advanced by different experts. All pandemics seem to attract a small coterie of advocates for an earlier precursor. That some earlier form was around is almost inevitable, the genetics of bacteria and viruses is not limited by sexual reproduction. They all exists in a free for all genetic swap meet. And evolve far faster than the multicellular organisms.
What are the odds that you could find a similar genetic sequence almost anywhere in the world before Covid-19 ? And what are the odds that it could be the actual source?
I don’t know, and neither do you.
So typical –
> The natural origin theory was cemented by a manufactured consensus (behind closed doors) calling anything else a conspiracy theory.
You premise with a lie/distortion/absurd misunderstanding, with a conspiratorial foundation, and build from there. On that basis all evidence leads back to confirming the conspiracy theory.
Over and over and over. The same process. Topic after topic. And never a good faith interrogation of the starting premises.
Self-sealing all the way down.
It’s truly a mystery to me how someone can be so willfully impervious to open investigation.
Over and over and over. The same process. Topic after topic
Audit without end…
Everett –
That paper is an interesting read.
I kept reading to find an answer to why, if there was such widespread SCoV-2 globally prior to the outbreak in Wuhan, there wouldn’t be signals in morbidity and mortality. Seems to me they kind of hand-waved towards an answer, but ultimately wound up ducking.
“Can anyone here answer their spousal abuse question? Why no answers to their “Out Of Africa” hypothesis?”
Everett, you make a good point: it’s especially difficult to solve a problem when you can’t rely on any information not being twisted or partly covered up. The cause for most of the natural origin skeptics is not that science can’t be trusted, it’s that we need to be sure science does not get corrupted by political forces.
People like me whom most denizens of this blog call anti-science are really just average people, including scientists and engineers, who want to preserve the integrity of institutions, including scientific ones. Mistakes are harmful but coverups are worse. I don’t believe that Eddie and the others want anything more that to serve goodness. But when accountability is saved only for those who question authority and not for those who were corrupted by it then we have the stage set for bad things.
[More peddling, W]
“The common factor in ALL new pandemics is a transfer from animals to humans that results in the evolution…”
Izen, we have a natural pandemic about once per 100 years, however, we have had outbreaks both from zoonotic crossovers as well as lab leaks in a similar order. I encourage all to get a copy of Viral.
Joshua, there has been extensive reporting from Jeremy Farrar and others, as well as the infamous email to Fauci on Jan 31, 2020, from Kristian, that now show the initial analysis was far from discounting lab origin.
> People like me whom most denizens of this blog call anti-science are really just average people, including scientists and engineers, who want to preserve the integrity of institutions, including scientific ones.
Fundamental attribution error.
Over and over and over.
> that now show the initial analysis was far from discounting lab origin.
Indeed. More “proof” of the conspiracy that you knew was there all along. All you needed to do was find questions that prove it.
> I bet you didn’t
You bet I didn’t finish my Beliefs and Bets post. By chance I didn’t bet anything!
Audits, which never end, got precedence, e.g.:
https://inquisitivebiologist.com/2022/02/11/book-review-viral-the-search-for-the-origin-of-covid-19/
That author seems to forget how Climateball works. The luckarmest goal is not to prove or disprove anything, but to move the needle of the debate from rejecting climate contrarianism as a conspiracy theory to acknowledging that, at the moment, we cannot firmly reject or accept AGW. This is a subtle but important difference that seems lost on some commentators, including our Covidball visitors.
More importantly to me, the author also fails to realize that he accepts circumstantial evidence regarding China, but rejects the same kind of evidence regarding Matt King Coal. We already know that he “raised concerns” regarding the origin of HIV. What I failed to emphasize earlier is that William Hamilton, Matt’s source, died of malaria in the Congo forest, convinced that polio vaccination caused HIV.
Michael Worobey ought to know – he almost died too. He was there, as a young researcher eager to prove himself. You can learn about it in the video I cited earlier:
You can also hear about it in passim in the podcast episode.
“People like me whom most denizens of this blog call anti-science are really just average people, including scientists and engineers, who want to preserve the integrity of institutions, including scientific ones”
Nobody who spends years promulgating conspiracy theories in multiple unrelated areas is “average”.
At my house we have hypotheses. My wife hypothesizes the things I misplace are where I left them. A circulation model. My hypothesis is agents of the Chinese Communist Party enter our house and misplace my things. Both are plausible. Many misplacedirologists think an intermediate host, so far never identified, misplaces my things. My wife has no evidence mine is wrong.
Congress is holding hearings to prove I’m right. Wow!
Sheer insanity.
A question for our Freedom Fighters:
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993413/
That includes any research on the consequences of gun violence.
Does it stop being a conspiracy when it has been a law for 20 years?
‘merica, Live Caged Or Die!
I see here that when counter facts are raised the intellectual debate screeches to a halt and the defense defaults a counter narrative: but conspiracy ideation.
[Playing the ref. -W]
Ron,
No, the point is that there are other possible explanations for the results obtained with those samples. Could be false positives. Could be contamination. Could be real detections, but then the question becomes how did it get in those samples without there being any indication of an epidemic within that community? Maybe it’s possible, but it’s very difficult to explain and it seems more likely that one of the alternative explanations is the correct one.
FWIW:
It did not please Climateball auditors, so it may not please Covidball auditors either.
No false positives for months. Not one. Then suddenly false positives?
I love how Ron advances theories (across topic after topic) involving assertions of collusion to lie, hide, coverup, etc., and then pearl-clutches when someone points out that his theories hinge on assertions of collusion to lie, coverup, etc.
Ron, be proud of your conspiracy theories.
Conspiracies happen. No one here would doubt that they do. The problem is that each conspiracy theory has to stand a plausibility test. It’s just pathetic for you to advance conspiracy theories and then whine because people point out that you’re advancing conspiracy theories.
You could just get over it, and get on with the task of establishing the plausibility of your beliefs. That you instead choose to pearl-clutch is unfortunate, as it blocks any progression.
But you do this over and over and over across many topics. You can’t even start at the beginning, right here:
>Joshua, there has been extensive reporting from Jeremy Farrar and others, as well as the infamous email to Fauci on Jan 31, 2020, from Kristian, that now show the initial analysis was far from discounting lab origin.
You’re going for a collusion to hide and lie, right there. At the beginning
Take just that issue and work with it in good faith. Explore the plausible angles. I know you won’t do it. You never do. You’d rather retreat to pearl-clutch and to declare the purity of your interests as opposed to those who have a different perspective. Apparently being the victim over-rides interest in discussion. I’d say you’re being lazy, in not engaging in depth, but I know that’s not true because you clearly devote a great deal of time and effort to all of this.
But that’s OK, don’t take it personally. This style of engagement is ubiquitous in on-line exchanges. You’re far from unique in that regard.
ATTP: “…how did it get in those samples without there being any indication of an epidemic within that community?”
I would presume that in the early weeks of the spread the virus was not yet fully adapted to humans and thus the growth rate of infected population was slower and easily missed. The virus caused cold of flu-like symptoms (or none) for 90%. The few elderly who got hospitalized had doctors that likely labeled it pneumonia as a complication of heart failure, immune compromise or other co-morbidities. They had no test for Covid or reason to look for it, obviously. Even when we knew the virus was coming to our shores in the US we did not detect it spreading in the population until mid-February. We did not see major crowding of hospitals until late March.
Evolutionary analysis done on the virus in 2020 indicated its origin to first human adaptation in the wild as early as August 2019. So, you ask why do we even look at Wuhan since any big city will accelerate the propagation rate? My answer, just from observation, is that the geometric curve is fairly uniform. The stage where a municipalities hospitals became crowded with patients is in the same order that they had initial introduction months earlier. There is plenty of documentary evidence in Chan’s Viral that the Chinese were internally fighting the epidemic in Wuhan while silencing doctors. This ended when George Gau, the head of their CDC and author of the doctoral thesis on the 2012 Mojiang mine incident, started taking actions. That was mid-December if I recall. While physicians were being threatened, like the well-known, one that tried to warn his collogues, on social media, Gau was talking to the WHO. It was Gau’s cooperation that likely led the WHO’s Tedros to think China was cooperating. Gau is also the person who oversaw the inspection and sample collection in the wet market. He also cleared it as the origin, both due to lack of animal evidence as well as evidence of prior cases not linked to the market.
Ron,
Okay, so is your suggestion that it started in Italy as a milder version, mutated through transmission from human to human, and then became virulent enough to cause a pandemic which started in the market in Wuhan?
Also note that whatever theory T we prefer, it needs to account for that inconvenient fact:
No, I’m not saying who said this or from where I got this quote.
The truth is out there.
Kind of reminds me of the troofer movement. Or the WMD movement.
As for the potential of contamination:
There is something virus-like to teh Tweeter:
The Climateball bingo is everywhere.
Rumor has it that Alex Washburne was in the movie 12 Monkeys! You heard it here 1st from The Truthierest. 😀
If one could harness all the energy that goes into this and similar arguments, it would be a unique and powerful energy source.
One day the world will be powered by keyboards, Susan.
Mark my words.
The purest contrarian energy, so pure it will reverse the entropy of the universe.
> Okay, so is your suggestion that it started in Italy as a milder version, mutated through transmission from human to human, and then became virulent enough to cause a pandemic which started in the market in Wuhan?
Seems to me that would suggest that there would be different lineages spreading and evolving separately in parallel countries other than China. It seems that they have limited evidence (not complete genetic structures) in the testing they did in Italy to speculate about spread before January 2020, but my recollection of what was being discussed later is in line with this – where distinct lineages in Europe didn’t occur until later on:
Based on SARS-CoV-2 genomes, we reconstruct a partial transmission tree
of the early pandemic and coinfer the geographic location of ancestral lineages as well as the number of migration events into and between European regions. We find that the predominant lineage spreading in Europe during this time has a most recent common ancestor in Italy and was probably seeded by a transmission event
in either Hubei, China or Germany
https://www.pnas.org/doi/pdf/10.1073/pnas.2012008118
Would be nice if someone who was knowledgeable would clarify.
> I would presume that in the early weeks of the spread the virus was not yet fully adapted to humans and thus the growth rate of infected population was slower and easily missed.
Thereby Ron dismisses the lab leak theories that SCoV-2 was engineered to be highly transmissive in humans, and that’s why the pandemic happened – a theory that Ron espoused in this very thread.
SA,
It is also renewable! :^)
ATTP: “Ron,
Okay, so is your suggestion that it started in Italy as a milder version, mutated through transmission from human to human, and then became virulent enough to cause a pandemic which started in the market in Wuhan?”
No. I think the most plausible explanation to fit all the facts that we see is that novel SARS viruses, indigenous to horseshoe bats in southern Yunnan, Laos and Indochina, were being collected and brought to the WIV for study. We know that the SARS1 close cousin was announced found in 2015 in Shitou cave in Yunnan. We also know now that prior to that at least one close cousin of SARS2 was found about 100 K west of that cave in an abandoned copper mine in 2012 when 6 workers were trying to clear it and became ill with atypical pneumonia, the 3 eldest succumbing. The head of the WIV, Zhengli Shi, received lavage samples sent to her from the hospital in Mojiang from the miners and became keenly interested in this mine, traveling there at least once per year for the next 5 years, collecting thousands of samples, including 9 unique SARS viruses. We know that every coronavirus virologist in the world would have been interested in this find but Shi only published one paper in 2016 mentioning only one of the 9 SARS viruses in her catalog of samples and viral finds. She disclosed only the sequence of its RDRP gene and labeled it Bat-cov4991, which four years later she published again as RaTG13, the closest cousin of SARS2 in her collection. But she did not disclose the atypical pneumonia which sparked her interest in the collection of that virus in 2012. She did not even mention that she had renamed it from her previous publication of it in 2016, only admitting it later under accusations of falsification.
The FCS, and Eco Health’s cover up of their proposal to DARPA for the WIV to insert it into SARS is yet another data point that cannot be ignored, since no other SARS virus in nature has a FCS.
The third major data point is pangolin SARS found in a smuggler’s pangolin that is closer to SARS2 than RaTG13 except that it can’t be progenitor of SARS2 by natural evolution, according to the experts, because of the spike proteins being very dissimilar. The original March 2019 publication of the pangolin SARS, is followed up in the fall of 2019 with a flurry of pangolin SARS reported independent finds that under scrutiny turn out to be falsifications using the same March sample. Where did pangolin SARS come from? Eco Health conducted a study in 2020 of pangolins in the wild, looking at current samples as well as their archive of animal surveillance samples over that last 10 years and find no evidence of pangolin SARS, or any coronavirus of any type, in wild pangolins. The smuggled pangolin with SARS either got it from a horseshoe bat in its cage. But I am not a virologist and cannot say if this is plausible. I do not see anyone claiming that. Instead I see lack of interest in the subject. My conspiracy spidy sense tells me they fear that lab animals being sold into the smuggling trade is a plausible explanation. If this is the case it has no bearing on SARS2 other than to show the WIV and other labs may have been lax on their safety controls.
I would think the flury of activity on pangolin SARS, that coincided with the purported flurry of mitigation measures going on in the WIV could have been initiated in response to authorities discovery of the outbreak and taking steps.
Just a theory. But, if China felt the virus originated in Italy I imagine that they would be publishing their own wastewater and medical sample surveillance data analysis showing exactly when and where in China the virus appeared.
Ron,
I’ve lost track of the relevance of samples in Italy in early 2019. Also, if your explanation is most plausible, why is it that – as far as I can tell – other experts cannot find any evidence of the WIV studying anything that could be a progenitor of SARS-COV2?
Think of it as a side bet, AT. Nothing prevents anyone from holding multiple theories at the same time. Diversification is the Holy Grail in many things.
Also note that Alina & Matt King Coal do not go as far as claiming it’s the most plausible theory, e.g.:
Lots of theories right there. At least four, three of them being from leakers. If all are equiprobable, then the leakers should give 2:1 odds, right?
Willard, there is about to be a new birth of ClimateBall in San Francisco, as the city celebrates Climate Week with a gala release of heavier than air poison gas balloons on behalf of a start-up that makes the Silicon Valley Bank look good:
https://vvattsupwiththat.blogspot.com/2023/03/celebrate-climate-week-with-your-own.html
“Just a theory.”
Just a conspiracy theory. That you then link to a whole cascade of collusion in lies and coverups.
Why is that so hard to for you to acknowledge?
Put down the pearls and be proud. You’ve put a lot of work into dreaming this up.
Very early, my two favorite locations for where SARS-CoV-2 originated were, and this has never changed: Laos, because whatever happens in Laos Vegas doesn’t necessarily stay in Laos Vegas; and two: Italy. Lots of illegal Chinese workers in Italy; lots of Chinese workers in Laos. Lots of people in Laos heavily engaged in the live animal trade in China.
ATTP: “Ron,
I’ve lost track of the relevance of samples in Italy in early 2019. Also, if your explanation is most plausible, why is it that – as far as I can tell – other experts cannot find any evidence of the WIV studying anything that could be a progenitor of SARS-COV2?”
The Italy, Brazil and I believe Spain wastewater and medical sampling surveillance studies show the SARS2 virus circulating internationally just prior to the earliest reported Chinese cases. This, along with the phylogenic analysis showing SARS2 well adapted to humans by the time of the first sampling in Wuhan cases, tells me the first human to human infections were likely in July-August in China. Wuhan is the first major city to see hospitals fill with Covid, thus I would say that this was the origin site, with no indication to the contrary. We don’t know what an Italy or Brazil type analysis of surveillance media would show. We don’t have access to China samples.
[But China. -W]
There are quite a number of people, however, that say the leak theory is plausible enough to end GOF research.
One more key scientific question is whether there needed to be a mammalian intermediary reservoir closer than bats to cross into humans, where human to human infection could continue. People get sick from animal viruses (zoonosis) all of the time, like the worker in the copper mine. But, having it then spread human to human afterward is extremely rare. In the 2015 interview with Baric on the TWIV link I posted he shrugs off the dangers of lab infection because of this. He said the lab worker just catches a cold.
One more thing I remember Baric saying is that he personally changed his view from SARS1 being caused by civet cats, and instead thought it might be a bat virus reservoir. I believe in 2010 they determined civets don’t carry SARS in wild. Also, we know Shi’s discovery of the SARS1 cousin in Shitou cave was just prior to that interview in Nov 2015. I note the similarity of the civet cat and the pangolin, both infected only in captivity, both pointed to as the intermediary, both acquitted.
> We did not see major crowding of hospitals until late March.
Italians might demur:
https://www.theguardian.com/world/2020/mar/09/italian-hospitals-short-beds-coronavirus-death-toll-jumps
Note the date.
Similar starting date for the US:
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257510/
Getting a correct timeline might improve our theories.
It’s noteworthy that Ron cites this:
Our observations suggest that by the time SARS-CoV-2 was first detected in late 2019, it was already pre-adapted to human transmission to an extent similar to late epidemic SARS-CoV. However, no precursor or branches of evolution stemming from a less human-adapted SARS-CoV-2-like virus have been detected. The sudden appearance of a highly infectious SARS-CoV-2 presents a major cause for concern
In support of this theory of this:
This, along with the phylogenic analysis showing SARS2 well adapted to humans by the time of the first sampling in Wuhan cases, tells me the first human to human infections were likely in July-August in China
It was “pre-adapted,” suggesting engineering. No, it evolved over months before the market outbreak. No, it was well-suited for transmission. No, it evolved over months on Europe. No, it appeared suddenly.
Anything will work when you’ve got a conspiracy to support. All you need to do is start with the conspiracy and then move everything around to fit it. It’s especially good when you can come up with questions with no answers where the answers that don’t exist could be dispositive. External validity for your theory need not be applied.
Willard, thank for your links. When I said late March I was talking about the US. Italy was about 45 days ahead of the US, declaring their lockdown on March 8, 2020. The US did not declare a European travel restriction until March 12. The first case in the Pentagon was March 24. https://www.defense.gov/Spotlights/Coronavirus-DOD-Response/Timeline/
In this Nov 2015 interview with Baric and Menachery At 0:07.00 into the recording Baric explains his belief that SARS1 came directly from bat to human, and it just coincidentally also was infectious to civet cats and racoon dogs also. He suggests there was interplay back and forth of human and captive civets infecting each other, which is a little weird to me but I recall in Viral that a case of that was documented. At 0:10.30 Baric mentions the re-outbreak of SARS in 2004 but omits to tell the audience that was from a lab leak in Beijing.
At 0:21.30 Baric describes the BSL3 conditions of the WIV work but we know now it was done in BSL2 protocol. At 0:22.00 he tells us all of the lab worker infections and how severe they typically are which is usually a common cold, “in fact every single time it has been a common cold.”
0:23:00 Baric describes the “pause” (2014 moratorium) and how they got in under the wire but would have to stop if they found their work produced an dangerously enhanced virus, which they tried to produce. He goes on from there to make the case for gain of function research to have tools when the catastrophic pandemic eventually comes. He obviously has a lot of respect and trust for the Chinese scientists. I think this is a case when an expert is too close to the issue to have clear judgment on policy.
The University of North Carolina is asking a judge to block the release of documents related to the research of Dr. Ralph Baric, a pioneer in the world of dangerous gain-of-function virus research.
He goes on from there to make the case for gain of function research to have tools when the catastrophic pandemic eventually comes. He obviously has a lot of respect and trust for the Chinese scientists. I think this is a case when an expert is too close to the issue to have clear judgment on policy.
Baric was pretty motivated to get money for his Lab.
also provided wuhan with humanized mice
and dont forget remdesevir.
> and dont forget remdesevir.
And remember the Alamo.
What is it that shouldn’t be forgotten about Remdesivir?
Did you want us to remember the Remdesivir conspiracy theories?
https://apnews.com/article/fact-checking-888870392951
Joshua, to more clear about how I understand a new virus enters the population, there are a few different scenarios. One is that someone gets infected by an animal virus and human virus of the same family at the same time. There are two natural human coronaviruses, for example, besides covid. There is now potential for recombination in individuals that are co-infected. All coronaviruses were originally bat viruses. In that scenario the new virus is already human adapted at its instant at coming into being. Something like this is what is thought to have produced the Omicron variant.
In a purely zoonotic crossover the virus will typically be non transmissible, but if it is just barely so, it will have the opportunity to slowly adapt and gain traction through random mutation events. Most mutations don’t even change the virus’s structure, and are known as synonymous mutations. They are different codons but they translate to the same amino acid. Virologists can analyze the rate of progression of these different random mutations, and even understand which ones prove beneficial and stick around instead of getting randomly replaced or necessarily replaced due to detrimental effect.
In the earlier the period since the crossover the more random mutations will stick as beneficial just by chance. As time goes on the RBD (receptor binding domain) codes to form stronger bonds with its new host and weaker bonds with its past host species, for example. So human corona viruses will likely not be able to infect bats even though its ancestor was a bat virus. SARS2 is found to have very poor ability to bind to bat’s receptors so they can tell it is pretty well along removed from bats. It’ss from looking at the evolution of the virus and these kinds of clues and measures that allow an extrapolation back to the crossover time point.
Ron –
I’m not interested in your theories except to the extent that they illustrate the logic of conspiracy ideation.
As far as I’m concerned you just work very hard to make stuff up support a conspiracy theory premise.
And I know from experience that it all boils down to “because the left.”
Again, the details don’t actually matter to me because I see them as arbitrary backfill.
> When I said late March I was talking about the US.
And when I quote We analyzed Health Pulse data to assess the extent to which US hospitals reported alerts when experiencing ED overcrowding, ICU overcrowding, and ventilator shortages from March 7, 2020, through April 30, 2021 I’m also talking about the US, Ron.
I should have emphasized US hospitals.
Sorry.
Oh, and if you could stop peddling your stuff about Baric, that’d be great.
I can’t remember if it was this podcast, or another one, but Eddie Holmes mentioned how his university was refusing to release his emails because of a duty of care to him. In other words, they didn’t trust the intentions of those who had requested them. Maybe we are learning something from Climategate.
ATTP: “…they didn’t trust the intentions of those who had requested them.”
Do you think that China’s lack of cooperation is legitimate? Because they are using that exact argument. This goes to the point I came here to make a couple of years ago when I posted here that every aspect of human advancement is related to the building of trustworthiness. The cycle of deterioration of trust is what leads ultimately to war, and in our age that could be an end to existence. I hoping that all could agree with that point, and thereby build a rope bridge between our seeming tribes.
[More peddling. -W ]
You need to trust The Truthierest, so give me your emails.
I’d settle for a quote to support the claim that Matt King Coal and Alina that say that the existence of the 8 unpublished viruses does not preclude a ninth top secret never to be published virus.
As is, the logic escapes me.
Ron,
But I would argue that it’s your “tribe” (to use your term) is the one that is demanding that others do things in order to gain your trust. I don’t think this makes any sense. We don’t live in societies where the mantra is “guilty until proven innocent”.
Your “tribe” can certainly decide to trust others until proven otherwise. I don’t think these “others” have some obligation to do things to gain your trust. That’s not how the world does, or – in my opinion – should, work.
Anyone found a Nature Trick yet?
Saving the popcorn.
Ron –
You start with a belief that people are lying and covering things up, and so then you interpret anything where a question might be asked as confirmation of that starting belief. The reason why you don’t trust is because you don’t trust. Usually, it’s “because the left,” which is an underlying causal mechanism you believe in, and that you’ve described countless times.
As an example, some of the scientists who were involved in the Proximal Origins paper changed their views on the likelihood of engineering, as shown in the emails.
You interpret that as evidence of a coverup. Because the question could be asked: “Why did they change their view?”
And then you move on from your assumed answer that they were covering up. You assume that answer because you don’t trust them. Since they covered up, everything they say is untrustworthy. And thus, anything they say is confirmation of the conspiracy.
You always know there’s a conspiracy because the people you accuse of conspiring deny that there’s a conspiracy. The denial is proof.
When did you stop beating your wife?
Don’t externalize your lack of trust and blame other people for it. When you fall into that pattern you will always find justification for your lack of trust.
You might start with examining whether or not most people are pretty much the same no matter where they lie on the left/right axis. If you find evidence of some significant difference in cognitive or or psychological attributes associated with ideological orientation, you could start with that for building your theory about the left/right divide. Have you even looked? I don’t think so. I think you just build your theory from a personal orientation. And thus any evidence you see, you just feed back into yorr already constructed algorithm for interpreting information.
Ron –
Because I know you believe that David Corn participated in the big media/deep state/big tech/lefty conspiracy to frame Trump in the “Russia hoax,” I offer this interview for you. See if you can approach what he says with trust.
https://bloggingheads.tv/videos/65894
> Anyone found a Nature Trick yet?
Please, let’s not go there.
I’d rather focus on what Matt King Coal & Alina concedes:
Not sure why they follow up with “it deserves its day in court,” however. Unless they think Napoléon code, they got their metaphor mixed up. Their book is about arguing that the lab leak hypothesis deserves its day in court. It should not be the other way around.
Hence another book that would have deserved an editor. I’m starting to be against books. In any event, it seems that Ron would need more than that book to argue that the lab leak is more plausible than the spillover.
That may explain why we’re onto emails right now.
Thought I’d take a quick look over at Eli’s and found this which was a response to Willard’s Postnormal item in February, but imnsho it applies here. I am particularly concerned about the pernicious effects of this kind of “flailing” leading to ignorant policy decisions. It highlights the way that “just asking questions” leads to handicapping our ability to deal with the remainder of the current pandemic and any future ones. The least useful and least reality-based voices have been loud enough to capture more than their share (which should be less than 1% but isn’t) of those in charge of making decisions.
Rasool & Schneider’s “Atmospheric Carbon Dioxide and Aerosols: Effects of Large Increases on Global Climate,” published in Science, New Series, Vol. 173, No. 3992 (July 9, 1971), 138-141, was wrong about its conclusion on CO2 (the aerosol part was useful.) Shortly, in 1972, vol 175 of Science, page 96, Rasool & Schneider wrote a letter in response to specific criticisms from Charlson, Harrison, and Witt. The authors admitted these objections and added a new defect others had failed to yet bring up. And, by 1974, Schneider (and others) provided refined models that reversed the earlier estimates, so as to “see” warming effects in the much nearer term.
All experts have mistaken ideas. Even the better of them. It takes time to imagine and process and discuss and weigh.
Allow time for expert consensus to arrive/precipitate.
ATTP: “But I would argue that it’s your “tribe” (to use your term) is the one that is demanding that others do things in order to gain your trust. I don’t think this makes any sense. We don’t live in societies where the mantra is “guilty until proven innocent”.
Your “tribe” can certainly decide to trust others until proven otherwise. I don’t think these “others” have some obligation to do things to gain your trust. That’s not how the world does, or – in my opinion – should, work.”
Trust is a very short and simple word that everyone takes for granted they understand. All I am trying to say is that its so central to our world and its prospects that its worth having some thoughts about. Try raising a dog without making it a point to have strangers greet and pet it when you walk it. I’ve seen people raise pets like that (not intentionally to create a guard dog). Do strangers walking by a dog have an obligation to ask the owner if they can greet and show friendliness to their dog? Does the owner have an obligation to open their mouth to the stranger? Animals are a great place for all people to agree that kindness and respect and the trust that it brings is a universal good. Does this set the dog up to be taken advantage of by a bad stranger? Well, yes. But let’s deal with that separately I say.
Willard: “I’d settle for a quote to support the claim that Matt King Coal and Alina that say that the existence of the 8 unpublished viruses does not preclude a ninth top secret never to be published virus. As is, the logic escapes me.”
I am not sure what you are asking. The 8 unpublished viruses had been submitted for publication before the pandemic. Shi knew that were going to be revealed but did not mention them for 11 months, just like she didn’t mention that RaTG13 was associated with workers sick with atypical pneumonia, which sparked her interest to collect samples at that location for 5 years, which resulted in the RaTG13 and 8 other SARS viruses being the top of her current study. She just didn’t think people would have the right idea about it I guess. They might think that if she had kept these viruses so close to the chest perhaps there was another, the treasure of the cache, that she never intended to share with the international virologist community (but that she accidentally shared with the planet).
Ron,
I’m not saying we shouldn’t think about it. I’m suggesting that if one group doesn’t trust another, they don’t have some right to expect the latter group to somehow prove that they can be trusted. Firstly, it’s probably not actually possible (if you’re pre-disposed to not trust someone, there is probably little they can do to change your view) and it’s not really how our societies work (it’s innocent until proven guilty, not guilty until proven innocent).
> I am not sure what you are asking.
A quote, Ron. You said Matt King Coal & Alina said something. I want a quote.
That looks like this:
That I know Matt King Coal & Alina said. That does not support your belief that the lab leak is more plausible.
When I refuted your claim that the US “did not see major crowding of hospitals until late March,” you feigned ignorance. I asked you to support your claim regarding what Matt King Coal & Alina said many times now, and you still feign ignorance. And we now know that your belief that the lab leak as more plausible isn’t supported by their political hit job.
So I duly submit that you’re in no position to epilogue on trust anymore.
Oh, and the Shi conspiracy is being addressed starting at 59:00 of the podcast.
The basic premise of trust would be that Chinese scientists attain professional status by publishing significant a it djdix achievements in credible scientific journals. In fact, they are under pressure to do so.
A basic premise of a non-trusting conspiracy theorist would be that a Chinese scientist would be hiding significant scientific achievements.
… significant scientific achievements….
I’ll also note that a basic premise of trust would be that non-Chinese scientists, collaborating with a Chinese scientist who lied and hid information relevant to a lab leak that lead to tens millions of deaths, would not collude to protect that Chinese scientist.
A basic premise of a non-trusting conspiracy theorist….well, you get the idea.
A basic premise of a non-trusting conspiracy theorist would be that a Chinese scientist would be hiding significant scientific achievements.
no our conspiracy theory is that.
A. they were forced to retract certain publications
https://www.theguardian.com/world/2020/apr/11/china-clamping-down-on-coronavirus-research-deleted-pages-suggest
&
B were forced to have publications cleared prior to publishing
please you know next to nothing about academic publishing in China.
https://www.mpiwg-berlin.mpg.de/observations/1/end-publish-or-perish-chinas-new-policy-research-evaluation
plus wrt B it is unheard of
for government or agency to gag a scientist!!!! no government pressures scientists
was that a conspiracy?
There’s little douht that after the pandemic started, the Chinese government started limiting transparency and access to Chinese scientists working on pandemic-related research. There’s nothing remotely inconsistent between that and what I said.
And in fact, the closing off of the work of Chinese scientists EXACTLY reflects the concern about the negative effect of China-bashing and conspiracy mongering.
So good work, the policy change as described in that 2020 document is the predictable end result of the conspiracy-mongering of you and your “Conspiracy mongering, what conspiracy mongering?” buds (not that there weren’t other contributing factors as well).
.
But thanks for helping to make my case. Much appreciated.
https://journals.asm.org/doi/full/10.1128/msphere.00119-23
JCH –
https://andthentheresphysics.wordpress.com/2023/03/13/the-origins-debate/#comment-216607
And:
https://andthentheresphysics.wordpress.com/2023/03/13/the-origins-debate/#comment-216955
J: “And in fact, the closing off of the work of Chinese scientists EXACTLY reflects the concern about the negative effect of China-bashing and conspiracy mongering.”
There is no action that can’t be rationalized by the logic of justified lack of trust or justified lack of trust that the other will trust you and thus can’t be trusted and thus etc…
You win every time with that one. But it also is the basis of most regulations that the building to a peacetime military. BTW, China used their Walmart dollars to build the largest army and navy in the world.
Ron –
I’m not exactly sure what you’re saying.
I’m not defending or justifying China’s lack of transparency (which predated the pandemic).
Perspective-taking and taking into account likely consequences doesn’t imply appeasement, it’s a critical aspect of managing diplomacy.
Unfortunately, an important aspect of the whole origins question has been the political expediency of China-bashing for the domestic audience.
Anyone who ignores that aspect is suspect. Worse are the people who play games by playing the conspiracy victim card, by ignoring the China bashing that’s been there.
As much as it’s important to not close out any legitimate potential of a lab leak origin, it’s also important to not play games as if politically expedient China bashing hasn’t been often part of *SOME* of the lab leak rhetoric since the very beginning.
Just as it’s a mistake to equate advocating for the exploration of a lab leak with China bashing, it’s also a mistake to ignore the China bashing component – both because it muddies finding the origin but also because of the geopolitical implications.
Worse than that, J. If we take the conspiracy srsly, we are led to a different conclusion than what our Freedom Fighters keep peddling:
Op. Cit.
All you need is to read the resources they themselves offer.
As usual with that kind of audit, the Fight for Freedom takes priority.
[But China, -W]
Alright, Ron.
Time to step away from that horse. Please return to the podcast episode, and find your book back. I am still interested in a quote for the claim you used as the foot on door for your week of peddling.
W: “Scientists believe the transmission was similar to that in the 2002 outbreak of Sars. Some criticism of China has focused on why the government did not shut down wet markets after the previous outbreaks of coronaviruses.”
I cited the 2015 audio clip of the most noted corona-virolgist in the world, Ralph Baric, stating that the 2002 outbreak was not from the wet market.” I pointed to the evidence that he may have been using in 2015 to come to that opinion, including the finding of no coronavirus in wild populations of the suspected animals. This also held true for the 2019 suspected animals. In addition, evidence has come to light in recent years of frequent innocuous zoonotic infections in local populations to the Yunnan bat caves by sero-prevalence studies for SARS-like antibodies. Add to this the covered up deadly infection of the copper mine workers in 2012, and there is plenty of evidence that the SARS virus could make a direct jump. Now, the timing of that risk is for evolutionary virologists to say, but from my understanding of their positions it is fairly small. It’s even hard for a bat virus to be able to jump to another bat species that regularly inhabits the same cave. Again, they may get exposed, but a virus that is not experienced with the specific species’s receptors, cell biology and immune defenses, has about as much chance of success as a tree getting struck by lightning two storms in a row.
Ron,
I was quoting from a piece one of your fellow Freedom Fighters cited. More importantly, switching to what Baric said in 2015 does not evade the reality that the wet market coverup was there to cover up the presence of an illegal wet market. Your irrelevant factoid only simulates a response to what I was saying.
So once again you are using a quote as a springboard to repeat arguments Matt King Coal & Alina made in a book you still refuse to quote.
Speaking of chances of success, how you can estimate virological probabilities is far from clear. Here is what we know:
What are the odds that you will stop peddling and listen to the podcast episode?
[Enough peddling, Ron. Come back in another thread. -W]
Ron –
Another podcast for you. At about 15 minutes in, a discussion with ChatGPT-4 about cognitive empathy. Might be something there for you.
https://nonzero.substack.com/p/a-chat-with-chatgpt-4-robert-wright#details
Marburg:
https://www.npr.org/sections/goatsandsoda/2023/03/31/1167093290/theres-a-second-outbreak-of-marburg-virus-in-africa-climate-change-could-be-a-fa
Joshua, I listened to the whole discussion and am kind of blown away. Even though I’ve tried out ChatGPT in text it’s amazing to see how conversational it is. I didn’t see it slip. The only omission I noticed is reference to is trust. For example, giving flattery can be widely misinterpreted as sarcasm by an enemy, so all attempts at pleasantness need to be tempered between individuals if they are not already on a trusted footing. For the reason that no one would question ChatGPT’s intentions but to be helpful is an amazing asset it could utilize. It’s clinical impartiality would make it an excellent family therapist or moderator for group therapy. Heck, people may greatly prefer the privacy of gaining individual therapy with it. I’m sure the uses for it are endless but I think it is has great potential as a conflict broker.
Ron –
It’s certainly amazing that it’s AI.
Yes, it kind of missed the boat on whether flattery can come across as phony, but a human might have missed any particular aspect also.
But what I really liked was how well it described cognitive empathy.
Went back and listened again, I see the cognitive empathy part starts at @13 minutes
JCH –
That article does a good job laying out why all the COVID origins and vaccine conspiracy mongering may lead to big problems.
And why the conspiracy victim card playing like Steven’s potentially makes it worse.
Yes, the one thing the commie pinko Generals and dictators have learned is the USA has around 70 million completely delusional and gullible fools who would, in the name of freeDUMBS, eradicate themselves in the presence of an engineered grand-slam virus.
A bit sideways, but the end of this Monbiot addresses the harm conspiracy mongering does to us all; I’ve started it a while before the relevant bits.